Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019621 (
Langerhans cell histiocytosis
)
3,250
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Langerhans cell histiocytosis
(
LCH
) is a rare disease with localized to disseminated clinical features. Thyroid involvement in
LCH
is rare and presenting as either a single-organ or multisystem disease, it is usually misinterpreted as another
thyroid disorder
. Therefore, the
LCH
diagnosis is often delayed. We report a pediatric case of
LCH
with thyroid involvement as the initial clinical manifestation progressing to respiratory failure. Clinicians should note insidious extrathyroidal laboratory abnormalities and consider infiltrative thyroid diseases, such as
LCH
. Systematic clinical and laboratory investigations are needed to prevent delayed diagnosis because the classic features of
LCH
may become evident only over time.
...
PMID:Delayed Diagnosis of Langerhans Cell Histiocytosis Presenting With Thyroid Involvement and Respiratory Failure: A Pediatric Case Report. 3168 61
