Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019621 (
Langerhans cell histiocytosis
)
3,250
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We report a 34-year-old man diagnosed with
Langerhans cell histiocytosis
(
LCH
) or
histiocytosis X
in 1980. He had multiple focal osseous lesions, difficult control of the disease activity and was treated many times with chemo- and radiotherapy for symptomatic control. His kidney disease started 20 years after the diagnosis with progressive renal failure and increasing non-nephrotic
proteinuria
, coinciding with two flares of
LCH
. A percutaneous renal biopsy demonstrated amyloidosis. There is only one case described in the amyloidosis literature associated with
LCH
.
...
PMID:Secondary amyloidosis associated with histiocytosis X. 1826 25
We report the case of a 37-year-old woman who presented with progressive renal dysfunction and
proteinuria
, in whom renal biopsy confirmed a diagnosis of AA amyloidosis. No evidence of chronic suppurative infection, connective tissue disease or malignancy was found. A past history of
Langerhans cell histiocytosis
(
LCH
) diagnosed in childhood was noted for which the patient had been successfully treated with surgical excision, corticosteroids, radiotherapy and chemotherapy. Renal disease in
LCH
is not widely recognized and thus we describe a patient with
LCH
in whom AA amyloidosis developed in the absence of any other established cause.
...
PMID:AA amyloidosis in a patient with Langerhans cell histiocytosis. 2598 25
