Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019621 (
Langerhans cell histiocytosis
)
3,250
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We report a case of a 13-year-old female with
Langerhans cell histiocytosis
(
LCH
) and primary hypothyroidism followed by
type 1 diabetes
mellitus (DM), both of which are rare complications. In
LCH
diagnosis, imaging studies showed an enlargement of the thyroid gland, suggesting the involvement of
LCH
cells. While the pancreas appeared normal, insulin secretion markedly deteriorated 11 months after cessation of chemotherapy. Even without direct pancreatic involvement, there is a possibility that
LCH
could induce DM as a part of its long-term complications. In particular, thyroid involvement may be related to the onset of DM.
...
PMID:A case of multisystem Langerhans cell histiocytosis with primary hypothyroidism followed by type 1 diabetes mellitus. 1936 15
