Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019270 (hernia)
 15,856 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In nine patients with left-sided congenital diaphragmatic hernia (CDH) developing within 24 hours of birth, the authors measured the dimensions of the bilateral main pulmonary arteries by echocardiography, and investigated whether the left:right main pulmonary artery dimension ratio (PAD ratio) was a useful index for predicting pulmonary hypoplasia and persistent fetal circulation (PFC). Echocardiography was performed shortly after admission, the PAD ratio was calculated, and the clinical course of each patient was determined. When the PAD ratio was approximately 1.0, patients did not suffer from PFC and had little evidence of pulmonary hypoplasia. When the PAD ratio was low, the patients suffered from PFC and had pulmonary hypoplasia on the side of the hernia. Thus, the PAD ratio measured by echocardiography appears to be a useful index for predicting pulmonary hypoplasia and the risk of PFC in patients with CDH.
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PMID:Usefulness of echocardiographic measurement of bilateral pulmonary artery dimensions in congenital diaphragmatic hernia. 803 70

The dynamic self-regulating prosthesis (protesi autoregolantesi dinamica, PAD) is a double-layered prosthesi, in use since 1992 in inguinal hernia repair. In 1999, we published the short-term results on 500 patients and herein we report the long-term follow-up. Five hundred eighty-five PAD procedures were performed on 500 adult male, unselected patients. Hernias were unilateral in 415 patients, were bilateral in 85 patients, were direct in 197 patients (33.7%), were indirect in 269 patients (46.0%), and were combined in 119 patients (20.3%). Four hundred sixty-four patients were alive at the follow-up period of minimum 5 years, whereas 36 died (7.2%) of causes unrelated to the hernia. No information was available on 73 patients (14.6%). Therefore, the follow-up was consisted of 391 patients (78.2%) with 469 hernias. The recurrence and testicular atrophy rates were nil. Three patients (0.77%) presented chronic pain and 18 (4.6%) suffered persistent discomfort or paresthesia. A hydrocoele was observed in one patient (0.2%). The long-term data confirm the efficacy of the dynamic self-regulating posthesis hernioplasty. We propose it as a standard of care in all cases of primary inguinal hernia in adult males, retaining it as a definitive and comfortable solution.
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PMID:Dynamic self-regulating prosthesis (protesi autoregolantesi dinamica): the long-term results in the treatment of primary inguinal hernias. 1655 27

We retrospectively analysed 236 consecutive patients with primary and recurrent inguinal hernia treated with the dynamic self-regulating prosthesis (PAD system). Parameters such as hernia type, operation time, type of anaesthesia, complications, hospital stay and recurrence were evaluated. Recurrence rates were determined by clinical examination. 254 PAD procedures were performed on 236 adult male patients. Inguinal hernias were unilateral in 218 patients, bilateral in 18 patients, and recurrent in 22 patients. There were 101 patients (43%) with Nyhus type II hernia, 113 (48%) with Nyhus type III hernia, and 22 (9%) with Nyhus type IV hernia; local anaesthesia was used in 149 (63%) patients, and epidural anaesthesia in the others. Haemorrhage occurred in 2 patients (0.8%) and required re-operation. After a median follow-up of 40 months (range: 21-56), there were only 2 (0.8%) recurrences, both in the same patient. Persistent inguinal pain at 1 year occurred in 3 patients (1.2%). There was no statistical correlation between preoperative comorbid disease, Nyhus type of hernia, operative time and recurrence (p < 0.2). We conclude that the PAD system is as effective as mesh repair with an acceptable recurrence rate and fewer complications.
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PMID:Inguinal hernia repair with the dynamic self-regulating prosthesis (PAD system). Recurrence and complications in 236 consecutive patients. 1796 77