Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019270 (hernia)
 15,856 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Three week old Schistosoma mansoni, cultured for up to sixty days after exposure to ethyl methane sulphonate, showed extensive ballooning which often involved most of the worm's body. Other changes included tegumental breakdown which was expressed in varying degrees from mild hernia to total disruption of body shape. Increase in gut size involved stretching of the epithelium and inclusions ranging from masses of disrupted tissue to large, dark opaque masses. Masses were also occasionally seen in the fluid filled spaces of worms. Evidence of hyperplasia was not observed in any of the histological examinations performed.
 ...
PMID:Morphological changes in Schistosoma mansoni caused by the mutagen ethyl methane sulphonate. 337 82

The results of cholecystectomy in terms of symptomatic improvement were prospectively evaluated in 124 unselected gall stone patients interviewed before and two years after elective surgery. Indications for cholecystectomy were biliary pain (n = 65), previous complications of gall stone disease (n = 52), and flatulent dyspepsia (n = 7). At two years 93 patients could be re-evaluated, of whom only 49 (53%) were completely symptom free. Postcholecystectomy symptoms occurring in the remaining 44 patients were mainly flatulent dyspepsia (which had relapsed in 22 of 46 patients who suffered it preoperatively), dull abdominal pain or diarrhoea. Incisional hernia was present in five patients and one had recurrence of pain because of retained common bile duct stones. Symptomatic cures after cholecystectomy decreased with the duration of the preoperative history. The results reconfirm that cholecystectomy eradicates specific symptoms and complications of gall stone disease, but they also show that nearly one half of operated patients are dissatisfied with the procedure because of mild but distressing 'postcholecystectomy' symptoms. These are probably caused by previously undiagnosed functional gut disease associated with, but unrelated to, gall stones. A systemic approach to multisymptomatic patients with gall stones is recommended.
 ...
PMID:Postcholecystectomy symptoms. A prospective study of gall stone patients before and two years after surgery. 342 78

We report a rare case of complete duplication of the bladder, urethra and external genitalia associated with other multiple congenital anomalies, such as ventriculoseptal defect, malrotation of the gut, ectopic anal opening, malascended left kidney, rachischisis of the lumbar spine and sacrum, and an umbilical hernia. To our knowledge the occurrence of these associated anomalies in a single case of complete duplication of the bladder, urethra and external genitalia has not been reported previously.
 ...
PMID:Complete duplication of the bladder, urethra and external genitalia in a neonate--a case report. 358 67

Colonic pseudo-obstruction (Ogilvie's syndrome) may occur in surgical patients, particularly those who have had orthopedic or blunt trauma, have uremia or diabetes, have complex metabolic or cardiac failure, have metastatic cancer involving the lymph nodes and neural tissue, or are addicted to narcotics. Although a single true cause has not been identified by fulfilling Koch's postulates, the clinical pattern has been recognized in a variety of surgical patients, and this pattern must be distinguished from true obstruction of the colon. Tumor or internal hernia may constitute an obstruction, but the important differential diagnosis of cecal volvulus must be excluded. Ischemic colitis may be confused with Ogilvie's syndrome or may follow it. Gangrene, infarction, and perforation may ensue as colon diameter increases and particularly if cecal distention reaches above 14 cm. This arbitrary number for cecal dilatation should not be awaited before treatment is instituted if signs of devitalization of the gut or peritoneal signs have developed in the patient. Treatment has changed recently with the widespread application of colonoscopy. Endoscopy is helpful in relieving distention but may also be dangerous in the patient with a massively distended colon, particularly at the level of the thin-walled cecum. Colonoscopy also appears to be associated with a high rate of treatment failure and recurrence. Surgical decompression may take the form of cecostomy or may require exteriorization or resection of the colon if infarction has occurred. A series of 12 patients has been presented. The patients were all referred to a single surgeon in a university medical center over a 4 1/2 year period with clinical patterns not suggestive of a common cause but a similar clinical evolution of Ogilvie's syndrome. The prognosis for such patients in whom the complication is recognized early and in whom decompression is performed endoscopically or surgically is encouraging. If recognition is late and particularly if perforation and gangrene result, mortality is nearly 50 percent.
 ...
PMID:Colonic pseudo-obstruction in surgical patients. 397 Mar 26

We report on complications of laparoscopic cholecystectomy which needed surgical intervention. These complications occurred in 10 out of 250 patients operated at our hospital and 2 patients admitted with complications. In 3 cases the common bile duct was cut and a hepaticojejunostomy was carried out. 3 patients with an insufficiency of the cystic duct were treated by laparotomy. In 2 cases common bile duct stones had to be endoscopically removed. 1 patient suffered from a pneumothorax due to damage of the diaphragm. The tear was laparoscopically sewn. In one case the abdominal aorta had to be oversewn because of its damage by the needle during creation of the pneumoperitoneum. One patient with adhesions suffered from a perforation of the gut as the trocar was introduced. 2 patients developed an umbilical hernia and underwent surgical herniotomy. In spite of all advantages minimal access surgery of the gallbladder seems to be affected with more serious complications than open approach.
 ...
PMID:[Complications after laparoscopic cholecystectomy]. 761 Jul 22

Internal abdominal hernias are rare and often are first seen when causing ileus. Three different internal hernias were operated on laparoscopically: a patient with a hernia duodeno-jejunalis causing recurrent pain in the upper bowel, vomitus and ileus; two patients with an intersigmoidal hernia and pelvic hernia causing ileus without prodroma. Each case was operated on laparoscopically during or short after ileus. In all cases the hernia could be assured and treated by retracting the gut into the abdominal cavity and either wide opening of the hernia's entrance or closing it by suture. It is concluded that internal hernias can be diagnosed and treated laparoscopically as well as in conventional operation techniques.
 ...
PMID:[Laparoscopic therapy for internal hernias. Presentation of three cases]. 808 86

The main symptom of the congenital diaphragmatic hernia (CDH) is the respiratory distress due to the pulmonary hypoplasia and the persistence of foetal pulmonary circulation. Sometimes the CDH appears outside of the neonatal period with respiratory symptoms, abdominal pain and seldom with intestinal obstruction. A case of CDH presenting with intrathoracic volvulus is reported. This case shows that tendency of delayed repair until the newborn has been recovered, require more attention because the good condition of the patient can be changed not only by the pulmonary hypoplasia and the persistence of the foetal pulmonary circulation but also by the symptoms of the intrathoracic gut complications.
 ...
PMID:Congenital diaphragmatic hernia and intrathoracic intestinal volvulus. 829 83

Three groups with n = 6 pigs were subjected to different techniques of endoscopic small bowel anastomosis. In Group I connection of the gut endings was done, using an all layer stapler-device, otherwise employed as hernia-stapler. Two thirds of the circumference became inverted, one third was everted. Anastomosis of Group II was done with the same stapler device, but all clips were set to evert the wound-endings. Group III consisted of triangularly shaped anastomosis, for which a linear stapler device was being used. All animals survived the investigation period (14 days) and were postmortally examined. Technical aspects and clinical results are being discussed.
 ...
PMID:[Various techniques for laparoscopic small intestinal anastomosis. A preliminary report]. 833 May

The authors discuss five older children where malrotation of the gut was diagnosed. The youngest child was three years old, the oldest 16 years. In three children the malrotation was diagnosed from clinical symptoms and examination by imaging methods, in two it was detected by chance during operation. In the two children where the impaired rotation of the gut was detected on operation, non-rotation was involved. In the remaining three children twice a left side paraduodenal hernia was diagnosed and once an external stenosis of the duodenum by Ladd's bands.
 ...
PMID:[Disorders of intestinal rotation and fixation in older children]. 862 73

A case of delayed separation of the umbilical cord is reported. Ultrasonography and radiographic examination of the stump showed connection with the bowel. During surgery the cord was found to contain the appendix. The authors hypothesize that this anomaly represents a small omphalocele, resulting from failure of the gut to withdraw completely from the umbilical cord, or, less likely, a hernia.
 ...
PMID:Delayed separation of an appendix-containing umbilical stump. 874 34


<< Previous 1 2 3 4 5 6 7 Next >>