Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019270 (hernia)
 15,856 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The plasma proteins pre-albumin, retinol-binding protein, transferrin, and haptoglobin were determined in 3 different groups of surgical patients (8 patients after inguinal or incisional hernia operation, 12 patients with peritonitis due to insufficient anastomoses, 17 patients with skull-brain injuries) according to the radial immune diffusion method. The decrease in concentration of nutrition-dependent plasma proteins, pre-albumin, retinol-binding protein and transferrin, varied depending on the extent of postoperative or posttraumatic catabolism and respective nutritional regimen. The increase in concentration of the acute phase protein haptoglobin was not significantly dependent on the severity of trauma. There was, however, a further haptoglobin increase of significance due to postoperative peritonitis complication.
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PMID:[Behavior of prealbumin, retinol-binding protein, transferrin and haptoglobin in the postoperative and post-traumatic phase]. 10 50

A cross-sectional study was conducted with 617 finishing pigs aged 10-25 weeks in 11 commercial herds of different health statuses as defined by the Danish monitoring program for specific-pathogen-free (SPF) herds. A standard clinical examination was performed and a blood sample was obtained from each pig for determination of haptoglobin concentration in serum. Pigs aged 10-14, 15-19 and 20-25 weeks in conventional herds had higher haptoglobin concentrations than high-health SPF (SPF-x) pigs of the same age. There was no significant difference between SPF-x pigs of different ages. Conventional pigs aged 15-19 and 20-25 weeks had higher haptoglobin concentrations than conventional pigs aged 10-14 weeks. Herd influenced the haptoglobin concentration. Lame pigs and pigs with tail or ear bite had elevated haptoglobin concentrations. No significant effect of respiratory symptoms or umbilical hernia was found.
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PMID:Serum-haptoglobin concentration in Danish slaughter pigs of different health status. 1216 49

The effect of 4 days total starvation (water only) in five normal subjects on the circulating concentrations of various proteins was studied. Changes in plasma albumin and total protein concentrations were compared with those of six patients undergoing elective abdominal surgery with partial starvation and six patients undergoing orthopaedic surgery with adequate feeding - (0.126-0.146 MJ/kg/day and 1.2-1.4 g protein/kg/day). In a companion study hand grip strength was measured daily in ten normal subjects during starvation and in 18 patients undergoing surgery for hernia repair (n = 6), cholecystectomy (n = 6) and major abdominal surgery (n = 6). Starvation produced marked reductions (approximately 30%) in the circulating concentrations of retinol binding protein and prealbumin but did not significantly affect the plasma concentration of immunoglobulins (IgG, IgA, IgM) acute phase reactants (orosomucoid, haptoglobin, alpha(1) antitrypsin), albumin and total protein. On the other hand both types of elective surgery produced significant reductions in plasma albumin and total protein concentrations irrespective of feeding. Grip strength was not significantly altered by four days of starvation but surgery produced a temporary reduction in grip strength, the extent and duration of which was related to the severity of operation. This study helps to separate the effect of surgery and starvation on hand dynamometry and circulating protein concentrations and indicates their limitations as indicators of nutritional state.
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PMID:Effect of starvation and elective surgery on hand dynamometry and circulating concentration of various proteins. 1682 52