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Drug
Enzyme
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Target Concepts:
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Query: UMLS:C0019270 (
hernia
)
15,856
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Three week old
Schistosoma mansoni
, cultured for up to sixty days after exposure to ethyl methane sulphonate, showed extensive ballooning which often involved most of the worm's body. Other changes included tegumental breakdown which was expressed in varying degrees from mild
hernia
to total disruption of body shape. Increase in gut size involved stretching of the epithelium and inclusions ranging from masses of disrupted tissue to large, dark opaque masses. Masses were also occasionally seen in the fluid filled spaces of worms. Evidence of hyperplasia was not observed in any of the histological examinations performed.
...
PMID:Morphological changes in Schistosoma mansoni caused by the mutagen ethyl methane sulphonate. 337 82
We report an 11-year-old boy who was diagnosed with schistosomiasis based on histopathologic examination of an inguinal hernia sac specimen. The child was an immigrant from Liberia and presented to our institution with inguinal and scrotal swelling. His past medical history was remarkable for previous ipsilateral
hernia
sac repair in West Africa, and at the time of his recurrent
hernia
repair, he was noted to have a peculiar loculated fluid-filled
hernia
sac, which was sent for pathologic examination because of its unusual appearance. Histologic examination revealed an intense infiltrate of eosinophils and numerous granulomas with ova of
Schistosoma mansoni
, and this speciation was confirmed with a stool wet prep examination for ova and parasites. Review of the English-language literature uncovered no prior cases of schistosomiasis presenting as an inguinal hernia. This unusual finding in a "routine" specimen, otherwise destined for the incinerator without pathologic evaluation, reinforces the importance of surgical vigilance in recognizing unusual or atypical features in these specimens.
...
PMID:Schistosomiasis: an unexpected finding in an inguinal hernia sac. 1799 Sep 28