Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019270 (hernia)
 15,856 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Histological diagnosis of space-occupying lesions in the anterior mediastinum is rarely possible using conventional radiological diagnoses; computer tomography in our opinion often makes this possible. Our experience is based on 47 tumours which have been investigated histologically. In the anterior upper or middle mediastinum there were thymic tumours (thymona, thymus hyperplasia or persistence of the thymus), retrosternal thyroids, malignant lymphomas, teratoid cysts, one seminoma and one aneurysm. In the anterior inferior mediastinum, we found pericardial cysts, lipomas and one Morgagni hernia. The computer tomographic features of these various lesions are described. Some tumours can be defined histologically by computer tomography alone, whereas others (e.g. solitary lymphoma, benign thymoma) make it necessary to consider the clinical features in addition. Computer tomography is particularly valuable in the diagnosis of persistence of the thymus, since standard radiography in two planes fails to show the lesion.
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PMID:[Computer tomographic characteristics of space-occupying processes in the anterior mediastinum and their differential diagnosis (author's transl)]. 645 67

Extrinsic left atrial compression is an uncommon source of hemodynamic compromise that can be caused by many mediastinal structures including bronchogenic cysts, carcinoma, lymphoma, thymoma, aortic aneurysm and diaphragmatic hernia. We describe an unusual case of a 26-year-old man presenting with symptoms of left heart failure. Transthoracic echocardiography demonstrated extrinsic left atrial compression caused by a metastatic testis non-seminomatous germ cell tumor. Compression of the left atrium caused impaired left atrial filling, leading to pulmonary venous hypertension and pulmonary edema. To our knowledge, the present case is the first reported case of mediastinal metastatic testis non-seminomatous germ cell tumor causing symptoms of left heart failure by externally compressing the left atrium.
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PMID:Mediastinal testicular tumor compressing the left atrium in a young male presenting initially with symptoms of left heart failure. 1918 28