Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019270 (hernia)
 15,856 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Intrathecal instillation of corticosteroid was used in treatment of 188 patients with persistent sciatica or lumbar pain caused by disc hernia or osteochondrosis and recurrent sciatica or lumbar pain after disc operation. 88 of 122 own patients were followed up. Indication, mechanism of steroid action, technic, complications and results are discussed. According to the good results in part of the patients, still after years, the authors believe, that intrathecal corticosteroid administration is a further useful method of conservative treatment of degenerative lumbar disc affections. This therapy can also be used in patients with recurrent, persistent lumbar or leg pain after disc operation.
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PMID:[Intrathecal cortison injection in lumbar disc problems (author's transl)]. 13 22

In order to elaborate an epidurographic technique, the water-soluble contrast substance (verografin), oil solution of iodine, iodolipol and air were used in experimental studies on animals and in cadavers. The studies demonstrated that oil and gaslike contrast substances penetrate into the vein and create a threat of embolia formation. For epidurography the most acceptable are water-soluble contrast substances. The method of an ascending verografin epidurography was elaborated and used in clinical practice. Some indications and contraindications for epidurography are outlined. A group of 396 patients with osteochondrosis of the lumbar part of the spine was examined. The method allowed a topic diagnosis of the disc hernia not only along the spine, but in the cross-section of the motor segments (median, paramedian and lateral hernias). The studies make it possible to exclude a disc prolapse in a nonhernial form of osteochondrosis. In 32 patients with spinal tumors epidurography permitted to determine the initial growth of the tumor, its size and relation to the dura mater.
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PMID:[Verografin epidurography in the diagnosis of spinal and spondylogenic diseases]. 45 88

A classification of changes in the inferior lumbar portion of the spine that cause radicular pain and symptoms not amenable to concervative therapy is given. In most cases the said changes can be educed through a clinico-roentgenological investigation. Anatomical data bear proof to the presence of structural variants in which, in case of an intercurrent osteochondrosis without hernia of the disc, the compression of the root becomes quite probable. The classification lists changes that should be looked for when no hernia of the disc could be detected and lays emphasis on the multiplicity of causes accounting for the emergence of vertebrogenic radiculitis.
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PMID:[Vertebrogenic lumbosacral radiculitis unrelated to disk herniation]. 119 4

Altogether 130 patients with associated lumbar spinal osteochondrosis and the radicular syndrome were placed under observation after operation in the form of laminectomy and removal of hernia of intervertebral discs. On days 2-3 after the operation the patients were given different physiotherapy modalities: sinusoidal modulated currents (SMC), electroacupuncture by sinusoidal modulated currents (EAP) and acupuncture (AP). The control group patients were administered conventional drug therapy. According to the data on the disease clinical picture and the rate of impulse conduction in the motor nerve, the treatment efficacy was higher in patients on physiotherapy as compared to the controls. In patients with the predominance of the painful syndrome, EAP and AP were most effective; EAP was most effective in associated pains and motor losses; SMC appeared effective in isolated motor disorders. The drugs slightly reduced the pains but did not recover motor function.
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PMID:[The physiotherapy of patients with lumbar spinal osteochondrosis in the early period after surgical treatment]. 133 16

Clinical, immunological, liquorological, roentgenological, rheovasographic, myelographic methods and computerized tomography (CT) were used to investigate 153 patients with spondylogenic lumbosacral radiculitts. The data expanded our knowledge of pathogenesis of neurological signs of lumbar osteochondrosis. Diagnostic capacities of CT in this ailment were for the first time assessed in comparison with other investigation techniques. Clinical CT syndromes of median, paramedian and posterolateral intervertebral disc hernia were depicted. Pathogenic grounds were offered to differential use of electroneurostimulation, reflex, manual, tractional therapies in the combined treatment of the disease depending on its actual stage. CT is recommended to evaluate the treatment efficiency.
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PMID:[Diagnosis and the main trends in the treatment of spondylogenic lumbosacral radiculitis]. 275 Mar 74

A study of reactive adhesive processes in the epidural space, radicles, and membranes of the spinal cord in 309 patients with lumbar osteochondrosis with radicular syndromes revealed hernia of lumbar disks in 296 patients (95.8%). In 45.6% of the patients disk hernias were attended by epiduritis. In 13 patients surgery revealed no disk hernia; one of them had aneurysm of the epidural space vessels, the rest had marked manifestations of epiduritis. In disk hernias with attendant epiduritis damage to two or three neural radicles was observed twice as frequently as in disk hernias without epiduritis. The diagnosis of cicatricial adhesive processes is based on clinico-neurological and roentgeno-contrast examinations (pneumoperidurography and peridurography with verografin.
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PMID:[Pathogenetic significance and diagnosis of adhesive processes in the radicular syndromes of lumbar osteochondrosis]. 341 44

The paper presents the results of tomographic studies of 119 patients with clinical manifestations of radiculopathy or radiculomyelopathy. MR tomography was performed on the Magnaview unit ("Instrumentarium", Finland) at field intensity 0.04 T. The analysis of T1- and T2-weighted sagittal tomograms providing MRT picture of osteochondrosis and various hernias shows that osteochondrosis involves several disks simultaneously while their bulging towards the vertebral canal is multiple. The severity of the hernia in some cases does not closely agree with degeneration degree or the decline of the vertebral disk height. However there is a close correlation between the size and direction of the hernia on the one hand and the clinical manifestations on the other hand.
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PMID:[Ultra-low magnetic resonance tomography of thoracic and lumbar spine osteochondrosis]. 799 Mar 53

The paper presents the technique and results of electromyography of the penis (EMP) for 68 males divided into 3 groups: 21 volunteers with erectile disorders, 20 patients with nonvasculogenic erectile dysfunction and no history of pelvic operations, 27 patients with erectile abnormalities as a result of pelvic operations (after cystectomy -11, cystoprostatectomy -1, rectal resection -7, rectal extirpation -8 patients, groups 1, 2, 3 and 4, respectively). Autonomic innervation of the penis is primarily characterized by such EMP parameters as amplitude, synchronism and frequency of potentials. Neurogenic penile disorder was identified in 3 patients of group 2 (1 patient with intervertebral disk hernia, 2 patients with lumbosacral osteochondrosis), in all patients of group 3 (electric silence was recorded in 22 patients). EMP should be included in the algorithm of examination of patients with erectile dysfunction as providing a reliable assessment of autonomic penile innervation.
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PMID:[Electromyography of the penis in the diagnosis of erectile dysfunction after radical operations on the organs of the lesser pelvis]. 957 4

36 intervertebrate disks (IVD) were studied in spinal osteochondrosis concurrent with herniation. Expression of herpes simplex types 1 and 2 (HSV-1 and HSV-2) antigens, which was absent in IVD of the control group (autopsy cases without disk hernia). The similarity of herniation in osteochondrosis and cardiac mesenchymal dysplasia, a frequent concomitance of these processes and the presence of HSV-1 and HSV-2 antigens in the IVD cells and cardiac valves may indicate the same nature of these diseases.
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PMID:[Spinal osteochondrosis, mesenchymal dysplasia and herpes infection]. 1729 Aug 88

Magnetic resonance imaging (MRI) was carried out in 24 patients with thoracic osteochondrosis. The obtained MR images showed the high efficiency of this radiodiagnostic technique in solving the tasks of visualizing a degenerative-dystrophic lesion of the vertebral column. MRI allows one to solve a broad spectrum of specific problems facing a radiodiagnostician and a neurosurgeon on examining a patient with thoracic osteochondrosis. This study permits an objective assessment of the stage of herniation and the degree of spinal cord compression, determination of treatment policy, planning of a surgical intervention, assessment of the results of surgical treatment, timely detection of possible complications, and visualization of recurrent hernia.
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PMID:[Magnetic resonance imaging in the diagnosis and treatment of hernias of thoracic intervertebral disks]. 1863 6


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