Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019270 (hernia)
 15,856 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Spinal myelitis caused by neurosyphilis is an extremely rare disease, and there are only few visual examples of magnetic resonance imaging scans. We present a clinical case of neurosyphilis, which is of great importance concerning diagnostic, differential diagnosis, and tactics of management. A patient complaining of progressive legs weakness, numbness, and shooting-like pain in the legs as well as pelvic dysfunction was admitted to the hospital. Neurological examination revealed spinal cord lesion symptoms: legs weakness, impairment of superficial and deep sensation together with pathological symptoms in the legs. Hernia of intervertebral disc or tumor was suspected, and myelography with computed tomography of the spine was performed. No pathological findings were observed. More precise examination of the patient (a small scar in the genitals and condylomata lata in anal region were noticed) pointed to possible syphilis-induced spinal cord lesion. Serologic syphilis diagnostic tests (Treponema pallidum hemagglutination assay, reagin plasma response, serum enzyme-linked immunosorbent assay) and cerebrospinal fluid tests (general cerebrospinal fluid test and Venereal Disease Research Laboratory test) confirmed the diagnosis of neurosyphilis. Spinal cord lesion determined by magnetic resonance imaging was evaluated as spinal syphilis or syphilis-induced myelitis. Conventional treatment showed a partial effect.
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PMID:Neurosyphilis manifesting as spinal transverse myelitis. 1677 68

28 year-old woman developed sensory loss in the gluteal region and involuntary micturition during sleep. After two days she arrived at the Department of neurology. Examination disclosed absence of the right ancle reflex (S1), sensory loss in the saddle area including the dermatomes S1-S5, absence of the ano cutan (S3-S5) and bulbocavernous reflexes (S3-S4). She had sphincter disturbance and a sensory palsy of the bladder, but no retention. She experienced no vertebral, radicular or other pain at any time. Because of the lack of pain, the tentative diagnosis was acute myelitis, and a CT scan was not done. A further investigation with MRI vas postponed to the next day. The MRI scan showed a large herniation of the L5/S1 disc, with significant affection of the cauda equina. The patient went to surgery with laminectomia and extirpation of the hernia. This case illustrates that a disk herniation with a cauda equina syndrome is not necessarily painful.
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PMID:[A 28-year-old woman with newly-onset urinary incontinence]. 1733 59

Acute flaccid paralysis (AFP), other than paralytic poliomyelitis, are usually due to demyelination like Guillian Barre syndrome (GBS), transverse myelitis and traumatic neuritis. Poliomyelitis like illness, Hopkins syndrome or Post Asthmatic Amotrophy, associated with bronchial asthma and hyperIgEemia has been reported in literature. We present a two and a half year old child who developed AFP with phantom hernia following an episode of bronchial asthma.
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PMID:Hopkins syndrome and phantom hernia: a rare association. 2174 15