Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019214 (hepatosplenomegaly)
 4,408 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
glucocerebrosidase 0.001
imiglucerase 0.001
Munc13-4 0.000
PRF1 0.000
SLC29A3 0.000
STX11 0.000
SMPD1 0.000
She 0.000
SLC7A7 0.000
LIPA 0.000
CD7 0.000
RAB27A 0.000
STXBP2 0.000
SLAM-associated protein 0.000
NPC1 0.000
TCIRG1 0.000
coiled-coil domain containing 115 0.000
ferritin 0.000
CD5 0.000
NPC2 0.000
OSTM1 0.000
T-cell immune regulator 1 0.000
TALDO1 0.000
chitotriosidase 0.000
CD56 0.000
SUMF1 protein 0.000
NCU-G1 0.000
PSAP protein 0.000
lysosomal sialidase 0.000
FHL3 0.000
lysosomal acid lipase 0.000
GSD1b 0.000
acid sphingomyelinase 0.000
Acid sphingomyelinase 0.000
lymphoid 0.000
TALDO 0.000
intelectin 2 0.000
CLCN7 0.000
MPS II 0.000
CD20 0.000
infantile malignant osteopetrosis 0.000
CD2 0.000
MPS7 0.000
FHL4 0.000
C16orf57 0.000
mevalonate kinase 0.000
NANH 0.000
NLRP11 0.000
MPS VI 0.000
LCAP 0.000
EIF6 0.000
hemoglobin 0.000
iduronate-2-sulfatase 0.000
TIA-1 0.000
CD13 0.000
alpha-L-iduronidase 0.000
CD8 0.000
CD10 0.000
LDH 0.000
CD33 0.000
Glucocerebrosidase 0.000
sphingomyelin phosphodiesterase 0.000
PLEKHM1 0.000
SLC17A5 0.000
CD4 0.000
CD30 0.000
NLRP9 0.000
MLPH 0.000
Ki-1 0.000
MANB 0.000
DNAJC21 0.000
white cell 0.000
70 kDa peroxisomal membrane protein 0.000
GLB1 0.000
perforin 0.000
lactate dehydrogenase 0.000
CHOP 0.000
CD19 0.000
T-cell receptor beta 0.000
VPS33A 0.000
more...
Disease
lymphadenopathy 0.016
pancytopenia 0.011
hemophagocytic lymphohistiocytosis 0.006
Gaucher disease 0.003
anemia 0.002
thrombocytopenia 0.002
kala-azar 0.001
Macrophage activation syndrome 0.001
familial hemophagocytic lymphohistiocytosis 0.001
Hepatosplenic T-cell lymphoma 0.001
Hemophagocytosis 0.001
Niemann-Pick 0.001
rash 0.001
hypofibrinogenemia 0.001
polyclonal hypergammaglobulinemia 0.001
leukoerythroblastosis 0.001
chronic neutrophilic leukemia 0.001
POEMS syndrome 0.001
hypergammaglobulinemia 0.001
lymphocytosis 0.001
failure to thrive 0.001
Wolman disease 0.001
T-cell lymphoma 0.001
lymphoma 0.001
cholesterol ester storage disease 0.001
Reactive hemophagocytic syndrome 0.001
Griscelli syndrome 0.001
Zimmermann-Laband syndrome 0.001
EBV infection 0.000
Epstein 0.000
Systemic juvenile idiopathic arthritis 0.000
myelofibrosis 0.000
Omenn's syndrome 0.000
osteopetrosis 0.000
leishmaniasis 0.000
Cytophagic histiocytic panniculitis 0.000
lysosomal storage disease 0.000
leukemoid reaction 0.000
infectious mononucleosis 0.000
coagulopathy 0.000
hypersplenism 0.000
Sea-blue histiocytosis 0.000
Neonatal leukaemia 0.000
Adult-onset Still's disease 0.000
petechiae 0.000
schistosomiasis 0.000
Hepatosplenic schistosomiasis 0.000
angioimmunoblastic lymphadenopathy with dysproteinemia 0.000
Conjugated bilirubinaemia 0.000
Arcus lipoides corneae 0.000
cutaneous T-cell lymphoma, stage 0.000
Niemann-Pick disease, type E 0.000
Harderoporphyria 0.000
MPS VIII 0.000
nonautoimmune hemolytic anemia 0.000
Rutherfurd syndrome 0.000
Immunoblastic 0.000
angioimmunoblastic T-cell lymphoma 0.000
normocytic anemia 0.000
Louse-borne relapsing fever 0.000
AILD 0.000
congenital syphilis 0.000
autoimmune lymphoproliferative syndrome 0.000
Mevalonate kinase deficiency 0.000
primary myelofibrosis 0.000
juvenile myelomonocytic leukemia 0.000
histoplasmosis 0.000
hemolytic anemia 0.000
NPC 0.000
Niemann-Pick disease type B 0.000
Castleman's disease 0.000
pharyngeal neoplasm 0.000
gamma-Glutamyl transpeptidase deficiency 0.000
sialic acid storage disease 0.000
stage I chronic lymphocytic leukemia 0.000
mucopolysaccharidosis 0.000
leukemia 0.000
sialidosis 0.000
LPI 0.000
Adrenal calcification 0.000
more...
Symptom
hepatosplenomegaly 1.000
pallor 0.001
splenomegaly 0.001
hepatomegaly 0.001
fever of unknown origin 0.000
night sweats 0.000
abdominal pain 0.000
arthralgia 0.000
Ill 0.000
hypotonia 0.000
sore throat 0.000
decreased skin turgor 0.000
cough 0.000
chills 0.000
bone pain 0.000
diarrhea 0.000
Palmar erythema 0.000
anorexia 0.000
clubbing 0.000
fatigue 0.000
generalized rash 0.000
jaundice of the skin 0.000
vomiting 0.000
lethargy 0.000
respiratory distress 0.000
weakness 0.000
Cutaneous anergy 0.000
pedal edema 0.000
unable to sleep 0.000
tachypnea 0.000
rales 0.000
General symptoms 0.000
dyspnea 0.000
PUO 0.000
eye discharge 0.000
Kayser-Fleischer ring 0.000
S3 gallop 0.000
myalgia 0.000
Roth spots 0.000
cachexia 0.000
rigors 0.000
joint stiffness 0.000
right upper quadrant pain 0.000
adenitis 0.000
abdominal discomfort 0.000
headache 0.000
Darier's sign 0.000
shortness of breath 0.000
asthenia 0.000
leg edema 0.000
clumsiness 0.000
Fatigability 0.000
ataxia 0.000
myoclonus 0.000
dark urine 0.000
lassitude 0.000
seizures 0.000
oliguria 0.000
erythema 0.000
hypertonia 0.000
Neurologic symptoms 0.000
emaciation 0.000
hypoproteinemia 0.000
dysosmia 0.000
gumma 0.000
generalized abdominal pain 0.000
blurred vision 0.000
abdominal fullness 0.000
ophthalmoplegia 0.000
nocturnal cough 0.000
cerebellar ataxia 0.000
dysarthria 0.000
chronic cough 0.000
left upper quadrant pain 0.000
exertional dyspnea 0.000
livedo 0.000
nausea 0.000
Physical findings 0.000
intention tremor 0.000
scaly skin 0.000
more...
Drug
Galsulfase 0.000
Ceredase 0.000
Cerezyme 0.000
Cerezyme 0.000
Fursultiamine 0.000
Idursulfase 0.000
Miglustat 0.000
Maribavir 0.000
Pentostam 0.000
Aldurazyme 0.000
Aldurazyme 0.000
Glucantime 0.000
Tocilizumab 0.000
Fansidar 0.000
Fansidar 0.000
Myozyme 0.000
Fabrazyme 0.000
Lariam 0.000
Claforan 0.000
Ambisome 0.000
Lariam 0.000
Miltefosine 0.000
Gabexate mesilate 0.000
Prednisone 0.000
Ganciclovir 0.000
Bactrim 0.000
Tuberculin 0.000
Rituximab 0.000
Dermatol 0.000
Engerix-B 0.000
Anakinra 0.000
Prednisolone 0.000
Lugol's solution 0.000
MDS 0.000
Methylprednisolone 0.000
CSF 0.000
Filgrastim 0.000
Trib 0.000
L-Asparaginase 0.000
Filgrastim 0.000
Fludarabine 0.000
AmBisome 0.000
ARA-C 0.000
G-CSF 0.000
CFT 0.000
Cidofovir 0.000
Epoetin 0.000
Lactase 0.000
Epoetin alfa 0.000
Vitamin B12 0.000
NBT 0.000
Eculizumab 0.000
beta-Galactosidase 0.000
AHF 0.000
Acyclovir 0.000
BCG vaccine 0.000
Etoposide 0.000
Adriamycin 0.000
AIC 0.000
Kenyan 0.000
linolenate 0.000
Meth 0.000
Dasatinib 0.000
IL-1ra 0.000
Isotretinoin 0.000
Portal 0.000
Simvastatin 0.000
TEL 0.000
IFN-gamma 0.000
IL-2 0.000
Itraconazole 0.000
CTX 0.000
Gastro 0.000
DEX 0.000
ENT 0.000
Paraffin 0.000
Ketoconazole 0.000
AraC 0.000
Hypaque 0.000
CTX 0.000
more...
Enzyme
glucocerebrosidase 0.001
iduronate-2-sulfatase 0.000
mevalonate kinase 0.000
alpha-L-iduronidase 0.000
lactate dehydrogenase 0.000
acyloxyacyl hydrolase 0.000
CD13 0.000
alkaline phosphatase 0.000
CD10 0.000
branching enzyme 0.000
uridyltransferase 0.000
alanine aminotransferase 0.000
porphobilinogenase 0.000
TdT 0.000
sulfatase 0.000
histone-lysine N-methyltransferase 0.000
aspartate aminotransferase 0.000
granzyme B 0.000
glucosylceramide synthase 0.000
neuraminidase 0.000
5-oxoprolinase 0.000
asparaginase 0.000
acid phosphatase 0.000
transaldolase 0.000
BMT 0.000
neutral sphingomyelinase 0.000
sialidase 0.000
bromelin 0.000
aspartylglucosaminidase 0.000
coproporphyrinogen oxidase 0.000
GTI 0.000
alpha-mannosidase 0.000
fumarylacetoacetate hydrolase 0.000
lipase 0.000
beta-glucosidase 0.000
lipoprotein lipase 0.000
AST 0.000
beta-galactosidase 0.000
ceramidase 0.000
arylsulfatase A 0.000
gamma-glutamyl transpeptidase 0.000
beta-glucosidase 0.000
peroxidase 0.000
biotinidase 0.000
coproporphyrinogen III oxidase 0.000
focal adhesion kinase 0.000
thromboplastin 0.000
glutamic dehydrogenase 0.000
tryptase 0.000
endo-N 0.000
phosphomannomutase 0.000
chondroitinase 0.000
lysozyme 0.000
galactokinase 0.000
hexosaminidase 0.000
carboxypeptidase Y 0.000
legumain 0.000
phosphorylase kinase 0.000
galactocerebrosidase 0.000
mannanase 0.000
ACE 0.000
farnesyltransferase 0.000
carboxylesterase 0.000
beta-glucuronidase 0.000
prolidase 0.000
CNPase 0.000
p80 0.000
ceruloplasmin 0.000
phosphoglucomutase 0.000
LPL 0.000
porphobilinogen deaminase 0.000
farnesyltransferase 0.000
chalcone synthase 0.000
MDP 0.000
3-hydroxyacyl-CoA dehydrogenase 0.000
glutathione synthetase 0.000
monoacylglycerol lipase 0.000
3-hydroxyacyl-CoA dehydrogenase 0.000
type III procollagen 0.000
ERK 0.000
more...
Compound
Direct Fast Scarlet 4BS 0.000
DFH 0.000
His 0.000
Reticulin 0.000
Direct Red 23 0.000
CD 3 0.000
VP-16 0.000
Praziquantel 0.000
A 3 0.000
Hemoglobin 0.000
A-14 0.000
Cholestanol 0.000
Clin 0.000
NNN 0.000
Amphotericin B 0.000
Guo 0.000
MCNU 0.000
A 42 0.000
Gadolinium chloride 0.000
Ara-C 0.000
Trihexyphenidyl 0.000
Ara-C 0.000
FDP 0.000
Busulfan 0.000
DNA 0.000
Guo 0.000
Dec 0.000
Filipin 0.000
Tocainide 0.000
Homoharringtonine 0.000
PAS 0.000
uroporphyrin I 0.000
2,4-DNT 0.000
MTX 0.000
4-hydroxyphenylpyruvate 0.000
protoporphyrinogen IX 0.000
5-methyltryptophan 0.000
Glucosylceramide 0.000
Prednisolone 0.000
ANA 0.000
ANA 0.000
Prednisone 0.000
Methylprednisolone 0.000
Nitrobenzene 0.000
Florid 0.000
DIC 0.000
bis(2-chloroethyl) 0.000
Nandrolone 0.000
TETA 0.000
PPD 0.000
BCG 0.000
Isoproterenol 0.000
5-oxoproline 0.000
5-oxoproline 0.000
PPD 0.000
GPT 0.000
Oxcarbazepine 0.000
creatinine 0.000
A 1 0.000
NDS 0.000
3-hydroxybenzoic acid 0.000
coproporphyrinogen III 0.000
5-oxoproline 0.000
DPM 0.000
Deoxycoformycin 0.000
iduronate 0.000
Ceftriaxone 0.000
Rifampicin 0.000
CDA 0.000
Methotrexate 0.000
Cidofovir 0.000
Cyclosporine 0.000
CPH 0.000
5-Aza-2'-deoxycytidine 0.000
Toluidine blue 0.000
Formin 0.000
Parenteral 0.000
5-oxoproline 0.000
Ethambutol 0.000
Chlorambucil 0.000
more...