Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019214 (hepatosplenomegaly)
 4,408 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
coiled-coil domain containing 115 11.8
NCU-G1 10.8
PSAP protein 10.8
SUMF1 protein 10.8
GSD1b 10.5
intelectin 2 10.2
TALDO 10.2
T-cell immune regulator 1 10.1
TALDO1 10.0
SLC29A3 9.9
STXBP2 9.9
OSTM1 9.9
STX11 9.8
MPS7 9.8
FHL4 9.8
SMPD1 9.7
NLRP11 9.6
NANH 9.6
SLC7A7 9.6
TCIRG1 9.6
LIPA 9.5
Munc13-4 9.5
LCAP 9.5
EIF6 9.5
RAB27A 9.5
lysosomal sialidase 9.4
C16orf57 9.4
PRF1 9.4
infantile malignant osteopetrosis 9.4
FHL3 9.4
imiglucerase 9.2
NLRP9 9.0
CLCN7 9.0
DNAJC21 8.9
MANB 8.9
70 kDa peroxisomal membrane protein 8.8
PLEKHM1 8.8
SLC17A5 8.8
BTAF1 8.7
MLPH 8.7
TRNT1 8.7
VPS33A 8.7
Acid sphingomyelinase 8.7
RNASEH2C 8.6
sphingomyelin phosphodiesterase 8.5
TET2 protein 8.5
acyloxyacyl hydrolase 8.5
CGL2 8.4
PHKA2 8.4
SLAM-associated protein 8.4
AK2B 8.4
preferentially expressed antigen in melanoma 8.4
ATP6AP1 8.4
granzyme H 8.4
NPC2 8.4
Glucocerebrosidase 8.3
glucocerebrosidase 8.3
SRD5A3 8.3
chitotriosidase 8.3
PHKB 8.3
T cell receptor gamma chain 8.2
PHKG2 8.2
CD 16 8.2
SLC28A1 8.2
DGUOK 8.2
KIF23 8.1
NPC1 8.1
RHAG 8.1
gamma-glutamyl cyclotransferase 8.1
Mevalonate kinase 8.0
iduronate-2-sulfatase 8.0
activator of CREM in testis 8.0
MAGT1 8.0
GLB1 8.0
MYO5A 8.0
THTR-1 8.0
ABCD3 8.0
ABCD4 8.0
NEU1 7.9
SLC7A6 7.9
more...
Disease
Conjugated bilirubinaemia 12.8
Harderoporphyria 12.8
nonautoimmune hemolytic anemia 12.8
Niemann-Pick disease, type E 12.8
Arcus lipoides corneae 12.8
cutaneous T-cell lymphoma, stage 12.8
Rutherfurd syndrome 12.8
MPS VIII 12.8
gamma-Glutamyl transpeptidase deficiency 11.8
Sea-blue histiocytosis 11.8
Neonatal leukaemia 11.8
pharyngeal neoplasm 11.8
stage I chronic lymphocytic leukemia 11.8
Mononucleosis syndrome 11.2
Cytophagic histiocytic panniculitis 11.2
Disseminated paracoccidioidomycosis 11.2
Supranuclear ophthalmoplegia 11.2
Cholangiohepatitis 11.2
Syphilitic alopecia 11.2
Alder-Reilly anomaly 11.2
Chylomicronemia syndrome 11.2
Hepatosplenic T-cell lymphoma 11.1
Louse-borne relapsing fever 10.9
Adrenal calcification 10.8
Reactive hemophagocytic syndrome 10.8
Hepatosplenic schistosomiasis 10.8
Hemoglobin E trait 10.8
Hemophagocytosis 10.7
Eosinophilic leukemia 10.6
Macrophage activation syndrome 10.6
cholesterol ester storage disease 10.5
Zimmermann-Laband syndrome 10.5
sphingomyelinosis 10.4
Systemic juvenile idiopathic arthritis 10.4
Omenn's syndrome 10.4
Immunoblastic 10.2
Polymorphic PTLD 10.2
leukoerythroblastosis 10.2
alymphocytosis 10.0
Bilateral optic neuritis 10.0
Acute myelofibrosis 9.9
alpha-Mannosidosis 9.9
Niemann-Pick disease type B 9.9
chronic neutrophilic leukemia 9.8
Lipoatrophic diabetes 9.8
Polyclonal gammopathy 9.8
FHL4 9.8
Meningovascular syphilis 9.8
hemophagocytic lymphohistiocytosis 9.8
Griscelli syndrome 9.7
RHN 9.6
Hepatic schistosomiasis 9.6
Acute nephritis 9.6
ABO isoimmunization 9.6
Infantile malignant osteopetrosis 9.6
ASMD 9.6
TLPD 9.6
Congenital malaria 9.6
Mevalonate kinase deficiency 9.6
Wolman disease 9.6
Granulomatous hepatitis 9.5
sialic acid storage disease 9.5
polyclonal hypergammaglobulinemia 9.5
Splenic lymphoma 9.5
Lipemia retinalis 9.5
Glomeruloid hemangioma 9.5
pancytopenia 9.5
FHL3 9.4
familial hemophagocytic lymphohistiocytosis 9.4
AILD 9.4
Cross syndrome 9.4
Telangiectasia macularis eruptiva perstans 9.4
DEFECT 9.4
Lymphohistiocytosis 9.4
HIDS 9.3
angioimmunoblastic lymphadenopathy with dysproteinemia 9.3
Stauffer's syndrome 9.2
Acute hemolytic anemia 9.2
Pulmonary histoplasmosis 9.2
Congenital hepatic fibrosis 9.2
more...
Symptom
hepatosplenomegaly 12.8
decreased skin turgor 9.6
Palmar erythema 9.5
jaundice of the skin 8.8
Cutaneous anergy 8.5
pallor 8.4
unable to sleep 8.3
PUO 8.1
generalized rash 8.0
General symptoms 7.9
S3 gallop 7.7
eye discharge 7.7
Roth spots 7.6
Kayser-Fleischer ring 7.6
fever of unknown origin 7.6
night sweats 7.5
hepatomegaly 7.4
pedal edema 7.4
Darier's sign 7.2
splenomegaly 7.1
clubbing 6.9
Fatigability 6.8
rales 6.7
sore throat 6.4
gumma 6.3
dysosmia 6.3
Neurologic symptoms 6.3
dark urine 6.3
lassitude 6.3
adenitis 6.3
generalized abdominal pain 6.2
bone pain 6.2
right upper quadrant pain 6.2
rigors 6.1
clumsiness 6.0
chills 6.0
leg edema 6.0
arthralgia 6.0
nocturnal cough 6.0
hypotonia 6.0
joint stiffness 5.9
left upper quadrant pain 5.8
tachypnea 5.8
abdominal fullness 5.7
Ill 5.6
abdominal discomfort 5.5
Physical findings 5.4
scaly skin 5.4
lethargy 5.4
hypalgesia 5.4
intention tremor 5.4
emaciation 5.4
hypertonia 5.3
pachyonychia 5.3
hypoproteinemia 5.3
generalized pain 5.2
asthenia 5.1
oliguria 5.1
labored breathing 5.1
livedo 5.1
abdominal pain 5.1
anorexia 5.0
dyschezia 5.0
cachexia 4.9
myalgia 4.8
periorbital edema 4.8
blurred vision 4.8
cough 4.8
athetosis 4.8
Decreased activity 4.8
swollen joints 4.8
intestinal bleeding 4.8
shortness of breath 4.7
non-productive cough 4.7
productive cough 4.7
myoclonus 4.7
excessive sweating 4.6
chronic cough 4.6
Gastrointestinal symptoms 4.6
urethral discharge 4.6
more...
Drug
Galsulfase 11.2
Fursultiamine 10.5
Idursulfase 9.5
Cerezyme 9.4
Ceredase 9.2
Cerezyme 8.9
Maribavir 8.9
Aldurazyme 8.6
Aldurazyme 8.6
Miglustat 8.5
Myozyme 8.0
Fabrazyme 7.9
Pentostam 7.8
Lariam 7.3
Glucantime 7.3
Fansidar 7.2
Claforan 7.2
Fansidar 7.2
Ambisome 7.0
Lariam 7.0
Tocilizumab 6.9
Gabexate mesilate 6.6
Miltefosine 6.5
Bactrim 6.2
Engerix-B 6.1
Anakinra 5.8
Lugol's solution 5.8
Tuberculin 5.6
Ganciclovir 5.6
Prednisone 5.4
L-Asparaginase 5.4
Filgrastim 5.4
Filgrastim 5.2
Trib 5.0
Methylprednisolone 5.0
ARA-C 5.0
Fludarabine 4.9
Prednisolone 4.9
AmBisome 4.8
Epoetin 4.7
Cidofovir 4.7
Lactase 4.7
Rituximab 4.7
CFT 4.6
Epoetin alfa 4.6
MDS 4.5
Eculizumab 4.4
Vitamin B12 4.1
beta-Galactosidase 4.1
NBT 4.0
AHF 4.0
Acyclovir 3.8
AIC 3.8
BCG vaccine 3.7
Etoposide 3.7
linolenate 3.6
Dasatinib 3.6
G-CSF 3.5
Isotretinoin 3.4
Meth 3.4
IL-1ra 3.4
TEL 3.2
Simvastatin 3.1
Kenyan 3.1
Gastro 3.0
DEX 3.0
Adriamycin 3.0
Itraconazole 2.9
Ketoconazole 2.8
Portal 2.8
AraC 2.8
Paraffin 2.7
Hypaque 2.7
Infliximab 2.7
Infliximab 2.7
CSF 2.7
AMC 2.6
Azithromycin 2.6
Hypaque 2.6
Vitamin B 2.5
more...
Enzyme
glucocerebrosidase 8.6
acyloxyacyl hydrolase 8.4
iduronate-2-sulfatase 8.2
mevalonate kinase 7.7
alpha-L-iduronidase 7.6
porphobilinogenase 7.0
histone-lysine N-methyltransferase 6.8
uridyltransferase 6.7
5-oxoprolinase 6.4
branching enzyme 6.3
bromelin 6.0
aspartylglucosaminidase 6.0
GTI 5.9
glucosylceramide synthase 5.9
coproporphyrinogen oxidase 5.8
transaldolase 5.8
CD13 5.7
fumarylacetoacetate hydrolase 5.6
neutral sphingomyelinase 5.4
ceramidase 5.4
coproporphyrinogen III oxidase 5.3
TdT 5.3
biotinidase 5.2
arylsulfatase A 5.1
glutamic dehydrogenase 5.0
endo-N 4.9
phosphomannomutase 4.9
sulfatase 4.9
alpha-mannosidase 4.8
granzyme B 4.8
asparaginase 4.7
BMT 4.6
CD10 4.6
sialidase 4.6
galactokinase 4.5
lactate dehydrogenase 4.4
beta-glucosidase 4.3
legumain 4.2
beta-glucosidase 4.1
galactocerebrosidase 4.1
carboxypeptidase Y 4.1
chondroitinase 4.0
phosphorylase kinase 4.0
tryptase 4.0
mannanase 3.9
prolidase 3.9
AST 3.8
alkaline phosphatase 3.8
farnesyltransferase 3.8
CNPase 3.7
lipoprotein lipase 3.7
p80 3.7
acid phosphatase 3.7
neuraminidase 3.6
hexosaminidase 3.6
aspartate aminotransferase 3.5
alanine aminotransferase 3.5
porphobilinogen deaminase 3.5
gamma-glutamyl transpeptidase 3.5
3-hydroxyacyl-CoA dehydrogenase 3.4
glutathione synthetase 3.4
phosphoglucomutase 3.4
monoacylglycerol lipase 3.4
3-hydroxyacyl-CoA dehydrogenase 3.4
LPL 3.4
type III procollagen 3.4
alpha-L-fucosidase 3.3
carboxylesterase 3.3
farnesyltransferase 3.3
chalcone synthase 3.3
beta-galactosidase 3.2
MCS 3.2
dihydropyrimidine dehydrogenase 3.2
lipase 3.2
thromboplastin 3.0
LasR 3.0
MDP 3.0
cathepsin G 3.0
BMA 3.0
cholesterol esterase 2.9
more...
Compound
Direct Fast Scarlet 4BS 10.8
DFH 8.3
Direct Red 23 8.0
Reticulin 7.6
Cholestanol 7.3
A-14 7.3
CD 3 7.3
Gadolinium chloride 6.9
Trihexyphenidyl 6.8
MCNU 6.8
NNN 6.3
Tocainide 6.3
Homoharringtonine 6.3
Filipin 6.2
Praziquantel 6.2
uroporphyrin I 6.1
protoporphyrinogen IX 6.0
5-methyltryptophan 5.9
Glucosylceramide 5.9
Busulfan 5.8
4-hydroxyphenylpyruvate 5.8
Nitrobenzene 5.7
2,4-DNT 5.7
Florid 5.6
FDP 5.5
Nandrolone 5.4
TETA 5.4
Ara-C 5.4
VP-16 5.3
5-oxoproline 5.3
5-oxoproline 5.2
Oxcarbazepine 5.2
Amphotericin B 5.2
Ara-C 5.1
Methylprednisolone 5.1
3-hydroxybenzoic acid 5.1
NDS 5.1
coproporphyrinogen III 5.1
5-oxoproline 5.1
DPM 5.0
Deoxycoformycin 5.0
Guo 5.0
A 42 5.0
iduronate 5.0
Prednisolone 4.9
Cidofovir 4.9
CPH 4.8
Formin 4.8
Prednisone 4.7
MTX 4.7
5-oxoproline 4.7
Ethambutol 4.7
Chlorambucil 4.6
bis(2-chloroethyl) 4.6
5-Aza-2'-deoxycytidine 4.6
Mebendazole 4.6
Hemoglobin 4.6
Toluidine blue 4.6
A 3 4.6
Ceftriaxone 4.5
CDA 4.5
Guo 4.4
DMP 4.3
HBB 4.3
DMP 4.3
DIC 4.3
DMP 4.2
L-PAM 4.2
N-acetylmannosamine 4.2
L-PAM 4.2
Belt 4.2
ANA 4.2
ANA 4.2
GPT 4.2
6-Mercaptopurine 4.2
Ritonavir 4.2
ribose-5-phosphate 4.1
PPD 4.1
keratan sulfate 4.1
PAS 4.1
more...