Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019214 (
hepatosplenomegaly
)
4,408
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
She
273
Sep
268
lymphoid
174
hemoglobin
145
CD4
138
ferritin
124
CD8
123
alkaline phosphatase
93
glucocerebrosidase
89
lactate dehydrogenase
74
Mol
73
cytokine
66
CD56
65
CD20
62
CD5
60
HLA
54
LDH
54
erythroid
49
HLA-DR
48
IgA
47
non-Hodgkin's lymphoma
46
MRI
46
CD2
43
CD7
42
fibrinogen
42
imiglucerase
40
C-reactive protein
37
interferon
36
CD19
36
perforin
33
CHOP
33
CD10
33
nodal
32
CD68
32
IgE
31
thymus
31
TCR
28
natural killer cell
27
CD30
26
CD13
26
prothrombin
26
aspartate aminotransferase
26
ESR
26
NPC1
25
AML
25
collagen
25
interleukin-6
24
CD34
24
white cell
24
acid sphingomyelinase
24
CD33
24
SLAM-associated protein
23
CSF
23
acid phosphatase
23
glucosidase
22
membrane-bound
22
alanine aminotransferase
22
albumin
22
CD25
22
lipase
22
Fas
22
IgG3
21
myeloperoxidase
21
IL-6
21
mast cell
21
interleukin-2 receptor
20
insulin
20
CD1a
20
CD16
20
HDL
19
tumor necrosis factor
19
esterase
19
CD45
18
severe combined immunodeficiency
18
IFN
18
JAK2
18
ALL
18
X-linked
17
lysozyme
17
peroxidase
17
more...
Disease
lymphadenopathy
1093
anemia
749
pancytopenia
498
thrombocytopenia
481
lymphoma
427
cancer
350
leukemia
299
rash
259
tumor
236
Epstein
229
hemophagocytic lymphohistiocytosis
204
Gaucher disease
195
immunodeficiency
155
leishmaniasis
154
HIV
137
cytomegalovirus
134
sepsis
122
kala-azar
117
pneumonia
115
T-cell lymphoma
112
schistosomiasis
112
coagulopathy
111
tuberculosis
110
AIDS
105
Hodgkin's disease
103
sepsis
103
hepatitis
102
arthritis
102
cirrhosis
99
lymphocytosis
98
failure to thrive
95
EBV infection
95
malaria
95
Niemann-Pick
92
acute myeloid leukemia
88
myelofibrosis
87
hemolytic anemia
87
acute lymphoblastic leukemia
83
infectious diseases
80
B-cell lymphoma
77
portal hypertension
75
infectious mononucleosis
73
eosinophilia
72
rare disease
71
systemic lupus erythematosus
71
liver disease
68
myeloproliferative disorders
64
multiple myeloma
63
leukopenia
61
hypergammaglobulinemia
61
neutropenia
60
virus infection
60
disseminated intravascular coagulation
59
cholestasis
59
familial hemophagocytic lymphohistiocytosis
59
proteinuria
58
chronic myeloid leukemia
58
sarcoidosis
57
hypercalcemia
56
dysplasia
56
mental retardation
55
osteopetrosis
55
histoplasmosis
54
chronic lymphocytic leukemia
53
mental retardation
52
non-Hodgkin's lymphoma
52
thalassemia
51
lysosomal storage disease
50
acute leukemia
49
Mycobacterium
49
renal failure
48
brucellosis
46
primary myelofibrosis
46
petechiae
45
vasculitis
45
NPC
45
polyneuropathy
44
POEMS syndrome
43
hyperbilirubinemia
43
respiratory failure
43
more...
Symptom
hepatosplenomegaly
4408
splenomegaly
193
abdominal pain
145
hepatomegaly
140
diarrhea
139
pallor
117
fatigue
116
cough
92
weakness
85
vomiting
81
Ill
73
headache
67
seizures
66
arthralgia
64
dyspnea
63
anorexia
63
respiratory distress
62
pain
58
fever of unknown origin
56
hypotonia
51
chills
38
sore throat
33
lethargy
33
bone pain
32
ataxia
30
night sweats
30
myalgia
26
erythema
25
nausea
25
cachexia
23
tachypnea
19
shortness of breath
19
myoclonus
15
back pain
15
clubbing
15
asthenia
13
dystonia
12
chest pain
12
abdominal discomfort
11
discomfort
11
sleepiness
11
discomfort
11
constipation
10
ophthalmoplegia
10
dysarthria
10
cerebellar ataxia
10
hemoptysis
9
joint stiffness
9
anesthesia
9
rales
9
dizziness
9
exertional dyspnea
9
oliguria
9
paresis
8
flushing
8
collapse
8
blurred vision
8
rigors
8
right upper quadrant pain
7
spasticity
7
chronic cough
7
cyanosis
7
hypertonia
7
low back pain
6
paresthesia
6
tremor
6
emaciation
6
regurgitation
6
leg edema
6
hypoproteinemia
6
adenitis
6
epigastric pain
5
generalized rash
5
pedal edema
5
ENT
5
clumsiness
5
rhinorrhea
5
angina
5
productive cough
4
tense
4
more...
Drug
Dermatol
98
CSF
27
IFN-gamma
11
IL-2
11
Rituximab
10
G-CSF
8
Asthma
8
MDS
7
Cerezyme
7
Tocilizumab
7
lysine
7
Prednisolone
6
Prednisone
6
Ceredase
6
ampicillin
5
ENT
5
Cardiovasc
5
Fansidar
5
Miglustat
5
Pentostam
5
vitamin E
5
Glucantime
5
Cerezyme
5
Ganciclovir
5
Fansidar
5
Adriamycin
5
CTX
5
Portal
4
Methylprednisolone
4
Kenyan
4
Tuberculin
4
CTX
4
Dial
4
lactose
4
Trib
3
NBT
3
PTH
3
CTX
3
Vitamin B12
3
Miltefosine
3
Indomethacin
2
Leaf
2
Idursulfase
2
Anakinra
2
CFT
2
Filgrastim
2
Fludarabine
2
Etoposide
2
Acyclovir
2
IL-1ra
2
Paraffin
2
Growth hormone
2
Meth
2
Itraconazole
2
Galsulfase
2
AmBisome
2
Simvastatin
2
Growth hormone
2
Bactrim
2
BCG vaccine
2
Filgrastim
2
Eculizumab
1
Nephron
1
Ambisome
1
DEX
1
Hypaque
1
Azithromycin
1
Epoetin alfa
1
Gastro
1
Monit
1
Dasatinib
1
Infliximab
1
Lariam
1
Lactase
1
CDP
1
Aldurazyme
1
Myozyme
1
Infliximab
1
Lariam
1
AZT
1
more...
Enzyme
alkaline phosphatase
93
lactate dehydrogenase
83
glucocerebrosidase
77
alanine aminotransferase
42
peroxidase
38
aspartate aminotransferase
35
CD10
33
focal adhesion kinase
30
CD13
26
neuraminidase
25
lipase
23
acid phosphatase
23
ERK
22
beta-galactosidase
19
lysozyme
17
thromboplastin
15
gamma-glutamyl transpeptidase
14
granzyme B
13
sulfatase
13
lipoprotein lipase
13
ACE
12
AST
12
mevalonate kinase
11
TdT
10
iduronate-2-sulfatase
10
alpha-L-iduronidase
10
asparaginase
10
reverse transcriptase
9
mitogen-activated protein kinase
9
BMT
9
sialidase
9
beta-glucosidase
8
beta-glucosidase
8
branching enzyme
7
beta-glucuronidase
7
hexosaminidase
6
trypsin
6
catalase
6
alpha-mannosidase
6
creatine kinase
6
tryptase
6
chondroitinase
5
plasmin
5
RNA polymerase
5
ceruloplasmin
5
transcriptase
4
neutral sphingomyelinase
4
APC
4
glucosylceramide synthase
4
carboxylesterase
4
MDP
3
carboxypeptidase Y
3
arylsulfatase A
3
transaldolase
3
uridyltransferase
3
glucose-6-phosphate dehydrogenase
3
caspase-3
3
ATPase
3
pyruvate kinase
3
endonuclease
3
thrombin
3
DCF
2
cathepsin G
2
farnesyltransferase
2
phosphoglucomutase
2
acyloxyacyl hydrolase
2
coproporphyrinogen oxidase
2
ceramidase
2
transglutaminase
2
P-glycoprotein
2
farnesyltransferase
2
aldolase
2
5'-nucleotidase
2
chalcone synthase
2
galactokinase
2
fumarylacetoacetate hydrolase
2
mannanase
2
protein kinase
2
protein kinase C
2
phosphorylase kinase
2
more...
Compound
Clin
361
Dec
313
DNA
201
His
109
iron
42
sodium
37
creatinine
33
glucose
28
calcium
28
oxygen
26
A 3
25
sulfate
24
Hemoglobin
24
leucine
19
galactose
19
TNF
17
VP-16
17
acetate
17
phosphate
16
water
16
PAS
15
urea
14
Guo
14
Guo
14
A 42
13
zinc
13
BCG
13
Amphotericin B
13
Cardiol
11
ANA
11
Isoproterenol
11
ANA
11
Ara-C
10
A 1
10
arginine
9
lysine
9
tyrosine
9
copper
9
Ara-C
9
methionine
8
MTX
8
Cyclosporine
8
Methotrexate
8
vitamin D
8
BCR
7
nitric oxide
7
nitrogen
7
ornithine
7
DIC
7
ornithine
7
ornithine
7
TSH
7
ornithine
7
silver
7
ornithine
7
Cholesterol
7
PPD
7
ammonia
7
PPD
7
Praziquantel
7
Prednisolone
6
iodine
6
Prednisone
6
Adriamycin
6
FDP
6
ALP
6
potassium
6
ABL
6
GPT
6
Parenteral
5
DBA
5
CTX
5
DTPA
5
DBA
5
DBA
5
bis(2-chloroethyl)
5
Pac
5
NNN
5
Rifampicin
5
Phe
5
more...