Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019214 (
hepatosplenomegaly
)
4,408
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In the past four months a new syndrome has caused more than 100 deaths in Spain. The most striking feature is a toxic-allergic pneumonopathy with respiratory distress and radiological evidence of interstitial (occasionally alveolar) exudation. Other features are fever, headache, nausea, muscular and abdominal pains, rash,
hepatosplenomegaly
, and eosinophilia; later, thrombotic phenomena and neurological disorders may appear. The epidemic has been traced to ingestion of rapeseed oil, denatured with
aniline
and containing acetanilide. The syndrome does not resemble intoxication with
aniline
or acetanilide, and is provisionally ascribed to "oleoanilide", a product formed by reaction of acetanilide with fatty acids.
...
PMID:Toxic-allergic syndrome caused by ingestion of rapeseed oil denatured with aniline. 611 11
