Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019214 (hepatosplenomegaly)
 4,408 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Clinical features observed in 60 cases of childhood HIV infection at the Cliniques Universitaires of Kinshasa is reported. Exposure mode, demonstrated in 92% of cases, was essentially maternofetal (65%) and related to blood transfusion (27%). The clinical signs appeared the first year of life in children born to seropositive mothers (82%). The main clinical features were: failure to thrive, high recurrent fever, persistent cough, chronic diarrhea, recurrent respiratory infections, hepatosplenomegaly, generalized lymphoadenopathy and oral candidiasis. Pulmonary lesions were very common (90%). These lesions were related to bacteria in 20 cases, to tuberculosis in 17 cases and to interstitial pneumonitis in 20 cases.
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PMID:[Clinical manifestations of AIDS in children in Kinshasa]. 166 39

We experienced a surgical case of large Hodgkin's lymphoma of the thymus. An 18 year-old male who had been complaining of a persistent cough was admitted to our hospital. Chest X-ray film showed an anterosuperior mediastinal tumor. But there was no superficial lymphadenopathy and hepatosplenomegaly. He received a surgical extirpation of the tumor approached by median sternotomy. The tumor expanded to the whole antero superior mediastinal region, which was 18.5 X 15 X 5.5 cm in size, surrounding the trachea and main branch of aortic arch and veins. The tumor directly invaded the bilateral pleura and left innominate vein, so these regions were resected with the tumor. The left innominate vein was reconstructed with a PTFE graft. The pathological diagnosis was Hodgkin's lymphoma nodular sclerosis type by LSG classification. A post operative course was uneventful.
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PMID:[A surgical case of Hodgkin's lymphoma originated from thymus]. 232 91