Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019214 (
hepatosplenomegaly
)
4,408
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Systemic Epstein-Barr virus (EBV)-positive T-cell lymphoproliferative disease (EBV
+
T-LPD) occurs mainly in Asia and South America and is extremely rare in adults. The disease is characterized by a clonal proliferation of EBV-infected T cells with a cytotoxic immunophenotype and is associated with a poor clinical outcome and can be life-threatening. The majority of the patients have evidence of systemic disease, often with lymph node, liver and spleen involvement. The present study describes a case of adult systemic EBV
+
T-LPD with high fever, systemic lymphadenopathy,
hepatosplenomegaly
, nose-
pharynx neoplasm
, pancytopenia, EB virus infection and proliferative bone marrow, with the aim of improving the understanding of the condition.
...
PMID:Adult systemic Epstein-Barr virus-positive T-cell lymphoproliferative disease: A case report. 2662 33