Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019214 (hepatosplenomegaly)
 4,408 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of Plasmodium vivax malaria in a 3-months-old-infant, born in the Netherlands from an Indian mother, is described. The infant was admitted the day after birth with a febrile illness of unknown origin and suffered thereafter from recurrent anaemia and hepatosplenomegaly. P. vivax was also found in the peripheral blood film of the mother. The concept of congenital transmission was also supported by the early presence of specific IgM-class antibodies in the serum of the infant. This is the first case reported from the Netherlands.
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PMID:Congenital malaria in The Netherlands. 635 85

Malaria is endemic in Malaysia. Leishmaniasis is a protozoan infection rarely reported in Malaysia. Here, a 24-year-old Nepalese man who presented with prolonged fever and hepatosplenomegaly is reported. Blood film examination confirmed a Plasmodium vivax malaria infection. Despite being adequately treated for malaria, his fever persisted. Bone marrow examination showed presence of Leishman-Donovan complex. He was successfully treated with prolonged course of amphotericin B. The case highlights the importance of awareness among the treating physicians of this disease occurring in a foreign national from an endemic region when he presents with fever and hepatosplenomegaly. Coinfection with malaria can occur although it is rare. It can cause significant delay of the diagnosis of leishmaniasis.
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PMID:Visceral leishmaniasis (kala-azar) and malaria coinfection in an immigrant in the state of Terengganu, Malaysia: A case report. 2153 57