Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019209 (hepatomegaly)
 5,798 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 367
alkaline phosphatase 258
She 211
insulin 195
hemoglobin 128
Mol 107
alanine aminotransferase 100
aspartate aminotransferase 98
lymphoid 98
albumin 79
microsomal 74
AST 65
prothrombin 58
glucose-6-phosphatase 56
GSD 55
endoplasmic reticulum 55
lactate dehydrogenase 54
CD4 53
ferritin 49
MRI 47
catalase 44
serum albumin 42
LDH 41
CD8 39
collagen 39
alpha-fetoprotein 37
peroxisome proliferator-activated receptor 36
thymus 35
cytokine 33
lipase 32
ESR 32
HLA 31
HDL 31
IgA 31
creatine kinase 30
glucagon 30
cytochrome P450 30
erythroid 29
AGL 29
lysosomal acid lipase 28
glucocerebrosidase 28
C-reactive protein 28
transferrin 27
CD20 26
fibrinogen 26
non-Hodgkin's lymphoma 26
surface antigen 25
xenobiotic 25
hemochromatosis 25
cytochrome P-450 25
GGT 23
G6Pase 22
glucose transporter 21
interferon 21
gamma-glutamyl transpeptidase 21
serum protein 20
long chain 20
CD10 20
CD34 20
GPT 20
adiponectin 19
white cell 19
carnitine acetyltransferase 19
membrane-bound 19
CD5 19
thromboplastin 18
TNF 18
IL-6 18
cytochrome 18
acid phosphatase 18
CRP 18
imiglucerase 18
growth hormone 17
Pol 17
carnitine palmitoyltransferase 17
X-linked 16
CD7 16
CD19 16
nuclear receptor 16
ATP 16
PPAR 16
LIPA 16
HLA-DR 15
SLC2A2 15
tumor necrosis factor 15
ALP 15
phosphatase 15
IgE 15
pregnane X receptor 15
granulocyte 14
polypeptide 14
acyl-CoA oxidase 14
CHOP 14
gut 14
leptin 14
PHKA2 14
reductase 13
peroxisome proliferator-activated receptor alpha 13
constitutive androstane receptor 13
glycoprotein 13
cyclin D1 13
nodal 13
FDG 13
mast cell 13
phosphorylase kinase 13
CD68 12
CLL 12
rheumatoid factor 12
gamma-glutamyltransferase 12
hairy 12
CSF 12
ALL 12
catenin 12
esterase 12
p53 11
ceruloplasmin 11
hepatocyte growth factor 11
GLUT2 11
B12 11
FAB 11
liver glycogen phosphorylase 11
proliferating cell nuclear antigen 11
thyroid hormone 11
glucosidase 11
GTG 11
peroxisome proliferator-activated receptor gamma 10
cytochrome c oxidase 10
Beckwith-Wiedemann syndrome 10
TdT 10
granulocyte colony-stimulating factor 10
vascular endothelial growth factor 10
AFP 10
Pseudomonas 10
rhabdomyosarcoma 10
CD33 10
Mal 10
CD25 10
MPS II 10
vimentin 10
Mem 10
ALD 10
AML 10
glucose-6-phosphate transporter 10
factor VIII 10
Alpha-fetoprotein 10
glycogen phosphorylase 10
HCC 9
chitotriosidase 9
CD45 9
lipoprotein lipase 9
amylase 9
argininosuccinate lyase 9
CAR 9
human leukocyte antigen 9
alpha 1-antitrypsin 9
S100 9
BSCL2 9
beta-catenin 9
CYP4A 9
IFN 8
more...
Disease
anemia 514
lymphadenopathy 441
tumor 398
cancer 362
cirrhosis 349
thrombocytopenia 331
liver disease 316
hepatitis 268
hypoglycemia 258
hepatocellular carcinoma 199
lymphoma 196
diabetes 187
portal hypertension 183
fatty liver 176
cholestasis 175
leukemia 151
rash 145
heart failure 140
glycogen storage disease 140
tuberculosis 125
amyloidosis 112
schistosomiasis 108
HIV 105
metastases 104
sepsis 103
Budd-Chiari syndrome 102
AIDS 98
congestive heart failure 98
pneumonia 94
cardiomyopathy 93
eosinophilia 92
sepsis 91
malaria 88
hyperlipidemia 88
immunodeficiency 88
obesity 87
carcinoma 86
hepatitis B 85
proteinuria 85
failure to thrive 84
infectious diseases 80
renal failure 77
pancytopenia 76
hyperbilirubinemia 75
dengue 74
leukopenia 72
pruritus 71
neutropenia 71
liver abscess 71
chronic liver disease 71
Epstein 67
myopathy 67
dysplasia 67
Gaucher disease 66
hypertension 65
lymphocytosis 63
veno-occlusive disease 63
leishmaniasis 63
liver fibrosis 62
coagulopathy 61
Hodgkin's disease 61
arthritis 60
cytomegalovirus 60
encephalopathy 59
lactic acidosis 57
acute myeloid leukemia 57
cholangitis 57
acute lymphoblastic leukemia 56
pericarditis 56
GSD 55
GSD 55
multiple myeloma 55
malnutrition 55
viral hepatitis 54
liver cancer 53
Schistosoma mansoni 53
renal disease 52
hyperglycemia 52
typhoid 50
carcinogenesis 49
chronic hepatitis 48
gallstones 47
Echinococcus 47
developmental delay 46
acute renal failure 45
chronic lymphocytic leukemia 45
rare disease 45
thalassemia 45
hypercholesterolemia 44
type 1 diabetes 44
virus infection 44
neuroblastoma 44
purpura 44
esophageal varices 43
liver cancer 43
pericardial effusion 42
sickle cell disease 42
disseminated intravascular coagulation 41
sarcoidosis 41
fits 41
systemic lupus erythematosus 41
hepatic veno-occlusive disease 40
Mycobacterium 40
polycystic kidney 39
thrombocytosis 39
depression 39
hemangioendothelioma 39
hepatitis C 39
nephrotic syndrome 39
brucellosis 38
hyperinsulinemia 38
GSD I 38
atherosclerosis 38
metabolic syndrome 36
peripheral neuropathy 36
hemorrhagic fever 36
hypercalcemia 35
hemolytic anemia 35
type 2 diabetes 34
heart disease 34
hemangioma 34
non-Hodgkin's lymphoma 34
Zellweger syndrome 34
hyperuricemia 34
infectious mononucleosis 33
chronic lymphocytic leukemia 33
vasculitis 33
Nonalcoholic fatty liver 33
coma 32
hepatoblastoma 32
T-cell lymphoma 32
liver metastases 32
polyneuropathy 32
obstructive jaundice 32
Infection 32
Wolman disease 31
tumorigenesis 31
acute hepatitis 31
kala-azar 31
hemochromatosis 31
myeloproliferative disorders 31
Niemann-Pick 31
biliary atresia 30
pulmonary hypertension 30
acute leukemia 30
chronic myeloid leukemia 30
West 30
chronic active hepatitis 30
alcoholic hepatitis 30
petechiae 29
metabolic disorder 29
cystic fibrosis 29
hemophagocytic lymphohistiocytosis 29
rickets 28
B-cell lymphoma 28
primary biliary cirrhosis 28
glucose intolerance 28
alcoholic fatty liver 28
adenoma 28
EBV infection 27
more...
Symptom
hepatomegaly 5798
splenomegaly 1222
abdominal pain 415
vomiting 227
diarrhea 219
anorexia 167
pain 162
weakness 145
hepatosplenomegaly 140
fatigue 122
dyspnea 120
nausea 102
lethargy 97
pallor 91
headache 86
hypotonia 84
cough 78
seizures 77
Ill 76
respiratory distress 56
arthralgia 56
right upper quadrant pain 55
myalgia 46
tachypnea 39
chills 38
cyanosis 32
fever of unknown origin 32
asthenia 28
abdominal discomfort 25
sleepiness 24
bone pain 23
shortness of breath 22
anesthesia 22
nausea and vomiting 22
chest pain 21
back pain 20
night sweats 20
cachexia 18
ataxia 18
erythema 18
constipation 18
epigastric pain 18
hemoptysis 18
emaciation 17
sore throat 17
exertional dyspnea 16
discomfort 15
discomfort 15
collapse 14
polyuria 14
hypoproteinemia 14
decreased appetite 13
dark urine 13
oliguria 13
leg edema 11
polydipsia 11
regurgitation 11
overweight 10
rales 10
abdominal fullness 9
syncope 9
ketonuria 9
Physical findings 9
hypothermia 9
orthopnea 8
acute abdomen 8
apathy 7
clubbing 7
prostration 7
rigors 7
angina 6
dysuria 6
numbness 6
paresthesia 6
flushing 6
pedal edema 6
tense 6
dysarthria 5
intestinal bleeding 5
lassitude 5
adenitis 5
spasticity 5
Cushingoid 5
productive cough 5
Cushingoid 5
starvation 5
dizziness 5
wheezing 5
agitation 4
low back pain 4
exhaustion 4
periorbital edema 4
thinning 4
Gastrointestinal symptoms 4
ophthalmoplegia 4
hemiplegia 4
photophobia 3
blurred vision 3
acute abdominal pain 3
muscle cramps 3
hypertonia 3
consciousness disturbance 3
joint stiffness 3
myoclonus 3
analgesia 3
paresis 3
tenesmus 3
shoulder pain 3
Respiratory symptoms 3
chronic cough 3
nasal discharge 3
tremor 3
non-productive cough 3
hip pain 2
hypercapnia 2
paraparesis 2
inanition 2
right lower quadrant pain 2
iliac fossa pain 2
labored breathing 2
colic 2
meningism 2
pleuritic chest pain 2
incoordination 2
PUO 2
enuresis 2
flank pain 2
Wind 2
rhinorrhea 2
clonus 2
cracked lips 2
Kayser-Fleischer ring 2
dry skin 2
acute pain 2
heartburn 2
cerebellar ataxia 2
insomnia 2
eye pain 2
jaundice of the skin 2
vertigo 2
hypocapnia 1
infant diarrhea 1
Girdle pain 1
stomach pain 1
hoarseness 1
functional recovery 1
hyperesthesia 1
tingling 1
bitter taste 1
stigma 1
excessive sweating 1
Joint tenderness 1
breath holding 1
DDS syndrome 1
leg pain 1
dystonia 1
neck stiffness 1
blepharospasm 1
dysesthesia 1
Murphy's sign 1
more...
Drug
Dermatol 52
Cardiovasc 23
ampicillin 18
CSF 15
Clofibrate 11
Portal 10
vitamin E 10
IL-2 8
Cerezyme 7
Ethanol 7
Albumin 6
Dial 6
Adriamycin 6
lactose 6
lysine 6
Propofol 6
Bezafibrate 6
Leaf 6
ascorbate 6
CTX 6
Prednisolone 5
EE2 5
Ceredase 5
Serum albumin 5
ENT 5
NADH 5
G-CSF 4
Prednisone 4
PPA 4
Dakar 4
Glucantime 4
Ciprofibrate 4
Glucagon 4
Rituximab 3
AmBisome 3
Cerezyme 3
IFN-gamma 3
Indomethacin 3
Kenyan 3
-deoxyadenosine 3
Gel 3
anti-CD33 3
ROS 2
Nephron 2
Gastro 2
VCR 2
ETS 2
Asthma 2
Nephron 2
Fructose 2
caffeine 2
Aldurazyme 2
MDS 2
Alanine 2
Anakinra 2
Lipiodol 2
Vitamin B12 2
Digenea 2
Phenytoin 2
Miltefosine 2
Doxycycline 2
Clonidine 2
Imatinib 2
Etoposide 2
Fluorescein 2
Vitamin A 2
Tuberculin 2
Gemfibrozil 2
IL-1ra 2
HCG 2
Vitamin B 2
Bifidobacterium 2
Azithromycin 2
Aldurazyme 2
Tacrolimus 2
MAP 2
FAD 2
Monit 2
DMSA 2
Tocilizumab 1
AZT 1
CPZ 1
Galactose 1
Hypaque 1
Orphan 1
Calamine 1
Simvastatin 1
Denopamine 1
Piperacillin 1
CAM 1
Streptokinase 1
Check 1
Ringer's solution 1
Bexarotene 1
Triad 1
PMEA 1
Adefovir dipivoxil 1
all-trans-retinol 1
Dextrose 1
Gelfoam 1
Pentostam 1
Idarubicin 1
TAC 1
Arsenic trioxide 1
Epoetin alfa 1
Dipyrone 1
Taxol 1
Imiquimod 1
Galsulfase 1
MEA 1
Midostaurin 1
Amprolium 1
VCR 1
Entecavir 1
niacin 1
Ganciclovir 1
Domin 1
Biltricide 1
ARA-C 1
Triad 1
Zileuton 1
Filgrastim 1
pyridoxal phosphate 1
Pimobendan 1
Ezetimibe 1
Ketoconazole 1
Bifonazole 1
OTC 1
Ovulen 1
SBT 1
BCG vaccine 1
PCB 1
Lenalidomide 1
Acyclovir 1
Thioguanine 1
Paromomycin sulfate 1
Hypaque 1
Neocarzinostatin 1
Campath 1
Methylprednisolone 1
Sodium citrate 1
Ranitidine 1
Eculizumab 1
Glybenclamide 1
Ipilimumab 1
Lactose 1
Senna 1
DEL 1
Campath 1
Abatacept 1
Ambisome 1
Troglitazone 1
Herceptin 1
CDP 1
OTC 1
Trib 1
ETA 1
Myozyme 1
Photofrin 1
Bumetanide 1
more...
Enzyme
alkaline phosphatase 258
alanine aminotransferase 222
aspartate aminotransferase 162
gamma-glutamyl transpeptidase 81
lactate dehydrogenase 68
AST 65
glucose-6-phosphatase 57
catalase 48
creatine kinase 39
lipase 33
glucocerebrosidase 27
phosphorylase 26
CD10 20
phosphorylase kinase 20
carnitine acetyltransferase 19
ERK 19
CPT 19
thromboplastin 18
acid phosphatase 18
acyl-CoA dehydrogenase 16
focal adhesion kinase 14
cytochrome oxidase 13
acyl-CoA oxidase 13
ceruloplasmin 12
demethylase 12
peroxidase 11
3-hydroxyacyl-CoA dehydrogenase 10
mitogen-activated protein kinase 10
aldolase 10
lipoprotein lipase 9
beta-galactosidase 9
glutathione S-transferase 9
transpeptidase 9
protein kinase 9
TdT 9
argininosuccinate lyase 9
soluble epoxide hydrolase 9
ACE 9
3-hydroxyacyl-CoA dehydrogenase 8
CYP7A1 8
HMG-CoA synthase 8
lysozyme 8
CD13 8
cholinesterase 7
reverse transcriptase 7
ECH 7
acyl-CoA dehydrogenase 7
neuraminidase 7
alpha-L-iduronidase 7
isoamylase 6
sulfatase 6
thrombin 6
superoxide dismutase 6
APC 6
pullulanase 6
alpha-glucosidase 6
UDP-glucuronosyltransferase 6
cholesterol acyltransferase 6
phosphoenolpyruvate carboxykinase 6
glycerol-3-phosphate dehydrogenase 5
fumarylacetoacetate hydrolase 5
citrate synthase 5
glycerol-3-phosphate dehydrogenase 5
glutathione peroxidase 5
complex I 5
asparaginase 5
CPR 5
uricase 5
microsomal epoxide hydrolase 5
glucose-6-phosphate dehydrogenase 5
amylo-1,6-glucosidase 5
phosphoenolpyruvate carboxykinase 4
palmitoyl-CoA hydrolase 4
acetyl-CoA carboxylase 4
phosphoenolpyruvate carboxykinase 4
glucokinase 4
AMPK 4
NQO1 4
tissue plasminogen activator 4
glycerophosphate acyltransferase 4
alpha-mannosidase 4
glutamine synthetase 4
alpha-L-fucosidase 4
luciferase 4
succinate dehydrogenase 4
P-glycoprotein 4
acetylcholinesterase 4
phosphofructokinase 4
transglutaminase 3
glutamate dehydrogenase 3
glutamate dehydrogenase 3
glutathione reductase 3
cholesterol esterase 3
hexosaminidase 3
trypsin 3
amylomaltase 3
ATPase 3
proteasome 3
tryptase 3
AMP-activated protein kinase 3
renin 3
diaphorase 3
ornithine transcarbamylase 3
beta-glucosidase 3
granzyme B 3
alpha-galactosidase 3
beta-glucosidase 3
dihydroxyacetone phosphate acyltransferase 3
pyruvate dehydrogenase 3
ATP synthase 3
DNA polymerase 3
caspase-3 3
acyl-CoA synthetase 3
phosphomannose isomerase 3
BMT 3
chondroitinase 3
phosphatidylethanolamine N-methyltransferase 3
collagenase 2
CPT 2
ornithine decarboxylase 2
type III procollagen 2
PARP 2
acyl-CoA thioesterase 2
heme oxygenase 2
protein kinase C 2
glutamate dehydrogenase 2
sterol carrier protein 2
glycine N-methyltransferase 2
lactic acid dehydrogenase 2
KAT 2
transcriptase 2
phosphomannomutase 2
AOR 2
cdc2 2
ornithine aminotransferase 2
PTPase 2
alpha-L-fucosidase 2
5'-nucleotidase 2
AMPK 2
LDT 2
MEK 2
lactic acid dehydrogenase 2
thymidine kinase 2
sorbitol dehydrogenase 2
mevalonate kinase 2
prostate-specific antigen 2
N-acetyltransferase 2
glucoamylase 2
acyl-CoA synthetase 2
beta-glucuronidase 2
methylmalonyl-CoA mutase 2
fructokinase 2
ALA synthase 2
lactic acid dehydrogenase 2
electron transfer flavoprotein dehydrogenase 2
calcineurin 2
CPT 2
diacylglycerol acyltransferase 2
DNase 2
NOS 2
more...
Compound
Clin 422
Dec 411
glucose 239
DNA 213
His 95
water 92
creatinine 77
ethanol 60
galactose 57
iron 50
phosphate 44
sodium 42
urea 42
oxygen 38
alanine 36
nitrogen 32
CoA 27
calcium 27
palmitoyl-CoA 27
Cardiol 27
DEHP 25
copper 24
2-ethylhexyl 23
2-ethylhexyl 23
Congo red 23
ammonia 23
2-ethylhexyl 23
Glycogen 22
arginine 21
GPT 20
PAS 20
tyrosine 20
zinc 19
A 3 19
leucine 19
TNF 18
potassium 18
sulfate 17
Hemoglobin 16
ATP 16
ABL 15
glycerol 15
ALP 15
methionine 14
L-carnitine 13
Clofibrate 12
glucose-6-phosphate 11
hydrogen 11
acetate 11
Cholesterol 11
DSS 11
Guo 10
Guo 10
barium 10
A 42 9
WY-14,643 9
Phe 9
DIC 9
Praziquantel 9
phosphorus 9
DHF 9
prostaglandin E1 9
Nodular 9
retinoic acid 9
BCG 9
HMG-CoA 9
ANA 8
acetic acid 8
DHA 8
5-FU 8
DBA 8
silver 8
SDS 8
Estrogen 8
ANA 8
NAD 8
Adriamycin 8
cyanide 8
Lactate 7
Luminal 7
Insulin 7
Pyrrolizidine 7
Oil Red O 7
DBA 7
vinyl 7
retinol 7
6-12 7
BCR 7
cysteine 7
Pac 7
salt 7
Oil Red O 7
GlcNAc 7
Bilirubin 7
A 1 7
palmitic acid 7
DBA 7
Optimal 6
DDT 6
CTX 6
Amiodarone 6
aniline 6
chloroform 6
aflatoxin B1 6
valine 6
Propofol 6
Ile 6
threonine 6
lysine 6
nitric oxide 6
glutamine 6
CCl4 6
iodine 6
Carnitine 6
palmitic acid 6
aldehyde 6
GSH 6
lauric acid 6
Isoproterenol 6
GSH 6
pyrene 6
Prednisolone 5
MMC 5
aceturate 5
TSH 5
Parenteral 5
isoleucine 5
CO2 5
benzene 5
tryptophan 5
propionic acid 5
FK506 5
Prednisone 5
Adrenal 5
propionic acid 5
pyrimidine 5
CAT 5
isoleucine 5
tryptophan 5
CAT 5
ammonium 5
Arsenic 5
pyrimidine 5
tryptophan 5
uridine 5
CAT 5
tryptophan 5
Perfluorooctanoic acid 5
Dial 5
NAD 5
benzoic acid 4
TCDD 4
Amphotericin B 4
Bantu 4
ACTH 4
Dexamethasone 4
dicarboxylic acid 4
selenium 4
Azathioprine 4
Triton 4
more...