Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019209 (
hepatomegaly
)
5,798
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
It acts of a retrospective study relating to 74 patients reached of chronic Leukaemia myeloid (
LMC
) over one 5 year period followed in the clinical service of hematology of the University Hospital of Yopougon (Abidjan, Ivory Coast). The splenomegaly is quasi-constant in chronic phase of the disease often associated
hepatomegaly
in 20.27% of the cases which constitutes a pejorative factor of the
LMC
. Indeed, the hyperleukocytosis of more than 300,000 white globules is correlated with the presence of
hepatomegaly
(p=0.0005) with risks of portal hypertension. 80% of the patients carrying the
LMC
with a clinical
hepatomegaly
in chronic phase of the disease have against an incomplete hematologic remission 20% of complete remission (P = 0.002) among patients without
hepatomegaly
. The strong rate of death (73.33%) recorded occurred among patients carrying a
hepatomegaly
against 15.25% of death without
hepatomegaly
(P = 0.0001). The overall rates Total survival is on average 17 months against 20 months 28 days in the event of absence of the
hepatomegaly
(P = 0.0001).
...
PMID:[Is hepatomegaly a prognosis factor of chronic myeloid leukaemia among African blacks?]. 1961 54
