Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019209 (hepatomegaly)
5,798 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 70-yr-old man with a large thoracoabdominal aortic aneurysm developed marked congestive hepatomegaly. Evaluation by arteriography, venography, and computed tomography revealed compression and venous obstruction at the confluence of the hepatic veins and inferior vena cava. Although obstruction of the inferior vena cava caused by rupture of an abdominal aortic aneurysm is known to occur, obstruction without rupture and involving the hepatic veins has not been previously reported.
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PMID:Marked hepatic congestion caused by a thoracoabdominal aneurysm. 648 2

Aortic pseudo-aneurysm is a rare manifestation of Takayasu arteritis. We present a 16-year-old girl who first complained of multiple arthritis, recurrent abdominal pain and malaise at the age of 15 years. The initial working diagnosis was juvenile rheumatoid arthritis. Follow-up abdominal ultrasonography for her hepatomegaly incidentally revealed an aortic aneurysm. Total aortography showed diffuse aortic narrowing and an infra-renal aortic pseudo-aneurysm. Vascular reconstruction with an interposition Dacron graft was performed with uneventful recovery. Early non-specific presentation of Takayasu arteritis often results in delay of diagnosis. The presence of a vascular bruit in a young female with non-specific symptoms should point to a differential diagnosis of Takayasu arteritis. We review the role of surgery in the management of this condition.
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PMID:Takayasu arteritis--a case report of aortic aneurysm. 1006 89