Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019204 (hepatocellular carcinoma)
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Human Gene/Protein
zinc finger protein 542 8.8
Beta-actin-like protein 2 8.8
HCC5 8.8
transmembrane protein 40 8.8
ZNF365 protein 8.8
OR1L3 8.8
Transmembrane protein 9 8.8
SNRNP27 8.8
LAMB1 protein 8.8
C9orf100 8.8
RecA homolog, E. coli 8.8
BRUNOL5 8.8
HCC 8.8
HCBP1 8.8
Glutathione S-transferase A3 8.8
FLJ33360 8.8
Ubiquitin-associated protein 2 8.8
chromosome 10 open reading frame 104 8.8
TCP10L protein 8.8
HCCA2 protein 8.8
DNM1P35 8.8
LOC100129335 8.8
PSKH2 8.8
MRIP-1 8.8
apoptosis-inducing factor, mitochondrion-associated, 3 8.8
Chromodomain helicase DNA binding protein 1 8.8
TIPUH1 8.8
tubulin, beta 2B 8.8
annexin IV variant 8.8
nuclear respiratory factor 2 alpha subunit 8.8
Kynureninase (L-kynurenine hydrolase) 8.8
eukaryotic translation initiation factor 3, subunit I 8.8
Complement factor H-related 3 8.8
ZNF233 8.8
Chloride intracellular channel protein 2 8.8
ACIN1 protein 8.8
GPATC4 8.8
enolase-phosphatase 1 8.8
T-complex protein 10A homolog 2 8.8
chromosome 21 open reading frame 91 8.8
SEC13-like 1 isoform 8.8
interleukin 28 receptor, alpha 8.8
vaccinia related kinase 1 8.8
MEOX2 protein 8.8
HCA90 8.8
ADFP protein 8.8
retinoic acid induced 16 8.8
ADAMTS9 protein 8.8
PNLIPRP3 8.8
HCCA2 8.8
zinc finger protein 292 8.8
non-protein coding RNA 52 8.8
hemoglobin alpha-2 8.8
methionyl aminopeptidase 2 8.8
nucleolar complex associated 2 homolog 8.8
Psoriasis susceptibility 1 candidate 1 8.8
NHE6.1 8.8
leucine zipper and CTNNBIP1 domain containing 8.8
C8orf33 8.8
spectrin repeat containing, nuclear envelope 2 8.8
ZCCHC4 protein 8.8
ZCRB1 8.8
CNN2 protein 8.8
MHC class II HLA-DQ 8.8
cytochrome b-type NAD(P)H oxidoreductase 8.8
PSG9 protein 8.8
Histidine triad nucleotide-binding protein 2 8.8
SPATA21 8.8
SH3 and multiple ankyrin repeat domains 2 isoform 2 8.8
CEBPD protein 8.8
TMEM78 8.8
Ubiquitin-conjugating enzyme E2 J2 8.8
Sex-determining region on Y 8.8
hydroxymethylglutaryl-CoA synthase 2 8.8
RCK protein 8.8
GTF2H1 protein 8.8
MAN1C 8.8
UCKL1 8.8
melanoma inhibitory activity 2 8.8
LRRC24 8.8
more...
Disease
Intestinal carcinoma 8.8
Perinatal hepatitis 8.8
hepatocellular carcinoma 8.8
Intrahepatic bile duct cancer 8.8
cystorrhagia 8.8
Cholangioma 8.8
Hepatobiliary neoplasms 8.8
Hepatocellular carcinoma 8.8
Metastasis to adrenal gland 8.8
Uterine Carcinosarcoma 8.8
Acquired porphyria 8.8
HCC 8.8
HC/HCC 8.8
Anemias due to chronic disorders 8.8
TSG11 8.8
adult primary liver cancer 8.8
Fibrolamellar hepatocellular carcinoma 8.5
hepatocholangiocarcinoma 8.4
HTC1 8.3
Hepatic vein occlusion 8.2
Intrahepatic biloma 8.2
Hepatocarcinogenesis 8.1
Macronodular cirrhosis 8.1
Primary liver cancer 8.0
Hepatoid adenocarcinoma 8.0
Tumor hemorrhage 7.8
Bile duct necrosis 7.8
TCPT 7.8
virus related cancer 7.8
Hepatocellular Adenoma 7.8
Early cirrhosis 7.8
liver cancer 7.8
Chronic hepatitis B 7.7
Chronic viral hepatitis 7.6
cholangioma 7.5
Kupffer cell sarcoma 7.5
liver cancer 7.5
Hereditary tyrosinemia type I 7.3
Radiation-induced liver disease 7.3
Metastasis to spleen 7.2
Other liver diseases 7.2
Morris Hepatoma 7.2
Cervical Squamous Cell Carcinoma 7.2
HHT4 7.2
Drug-induced depression 7.2
Amyloid neuropathy 7.2
Biloma 7.2
avian lymphomatosis 7.2
hepatic adenoma 7.2
pediatric liver cancer 7.1
Chronic hepatitis C 7.0
Other hepatitis 7.0
Chronic infection 6.9
cirrhosis 6.9
Micronodular cirrhosis 6.9
Sclerosing hepatic carcinoma 6.8
Glucagon resistance 6.8
Periarteritis 6.8
Coproporphyrinuria 6.8
childhood leiomyosarcoma 6.8
Postoperative stricture 6.8
Advanced chronic liver disease 6.8
Hepatic artery occlusion 6.8
Cardiac cirrhosis 6.8
Pericholangitis 6.8
Biliary carcinoma 6.8
arterial embolization 6.8
hepatic neoplasm 6.8
HEP 6.7
Sarcoma 37 6.7
TLPD 6.6
Portal vein occlusion 6.6
Tumor embolus 6.6
Focal nodular hyperplasia 6.6
MRX34 6.6
Cirrhosis 6.6
chronic hepatitis 6.6
chronic liver disease 6.5
Nonalcoholic fatty liver 6.5
FENIB 6.5
more...
Symptom
prickling sensation 4.9
Upper abdominal pain 4.5
right upper quadrant pain 4.4
rib pain 4.3
eye discharge 4.3
abdominal fullness 4.2
hepatomegaly 3.9
Acute dyspnea 3.8
epigastric distress 3.2
leg edema 3.1
Pain symptoms 3.0
abdominal discomfort 3.0
cachexia 2.8
intestinal angina 2.7
dark urine 2.7
abnormal breathing 2.6
Kayser-Fleischer ring 2.6
epigastric pain 2.6
Sister Mary Joseph's nodule 2.6
Spots 2.6
decreased appetite 2.5
No toxic effect 2.5
lumbar back pain 2.4
hypoproteinemia 2.2
abdominal pain 2.2
Scratch 2.2
autodigestion 2.1
pedal edema 2.1
localized edema 2.1
No adverse effect 2.1
left upper quadrant pain 1.8
anorexia 1.8
starvation 1.7
Signs and Symptoms 1.7
chromosome marker 1.7
generalized rash 1.6
voice change 1.5
splenomegaly 1.5
arm pain 1.4
frequent urination 1.4
asthenia 1.3
Flare 1.3
Decreased activity 1.3
peri-menopausal 1.3
acute abdominal pain 1.3
jaw pain 1.3
Tenderness 1.3
skin irritant 1.2
acute abdomen 1.2
bone pain 1.2
aphagia 1.2
nausea 1.1
nausea and vomiting 1.1
Cushingoid 1.1
flank pain 1.0
hepatosplenomegaly 1.0
Cushingoid 1.0
orthopnea 1.0
HSA 1.0
exhaustion 0.9
Ill 0.9
anal pain 0.9
stomach pain 0.8
Catch 0.8
lethargy 0.8
fever of unknown origin 0.8
emaciation 0.8
intestinal bleeding 0.7
consciousness disturbance 0.7
lassitude 0.7
leg pain 0.6
Fluctuation 0.6
fatigue 0.6
persistent cough 0.5
right lower quadrant pain 0.5
exertional dyspnea 0.5
DNA marker 0.5
vomiting 0.5
Physical findings 0.4
bloating 0.4
more...
Drug
Peretinoin 8.8
Truphylline 8.8
Smancs 8.1
Sorafenib 7.9
Liskantin 7.8
Sophora root 7.8
Paulomycin 7.8
Alisma rhizome 7.8
Lipiodol 7.8
IFEX 7.2
Livact 7.2
Edotecarin 7.2
Nexavar 7.1
MK-803 6.8
Monoammonium glycyrrhizinate 6.8
18DG 6.6
Sonazoid 6.6
Mesoheme 6.5
Syprine 6.5
Topotecan hydrochloride 6.5
Butyramide 6.5
Mangafodipir trisodium 6.2
Hepatitis B immune globulin 6.1
Tesamorelin 6.0
Diammonium glycyrrhizinate 6.0
Entecavir 5.9
Entecavir 5.9
C6F14 5.8
Ferumoxides 5.8
Span 65 5.8
Thymalfasin 5.7
Levovist 5.7
Bupleurum root 5.6
Hexobendine 5.6
OKG 5.5
Radicut 5.5
Nitisinone 5.4
Scutellaria root 5.4
Advexin 5.3
Carzelesin 5.3
Parecoxib sodium 5.3
Clevudine 5.3
Muromonab-CD3 5.2
Vitamin K2 5.2
Gelfoam 5.1
Doxifluridine 5.1
Semaxanib 5.1
Lifibrol 5.1
Telbivudine 5.0
Olomoucine 4.9
p-Chlorophenyl 4.9
Wellferon 4.9
Tesaglitazar 4.9
Viramidine 4.8
Gd-BOPTA 4.8
1-Deoxymannojirimycin 4.8
Romet 4.8
Aescin 4.7
Eulexin 4.6
Phenobarbital sodium 4.6
Gardenia fruit 4.6
Sodium ascorbate 4.6
Resovist 4.6
Lonafarnib 4.6
GEO 4.6
Medazepam 4.6
1,2,4-Triazole 4.6
Gelfilm 4.5
Ferric ammonium citrate 4.4
Neocarzinostatin 4.4
Dacogen 4.3
ATV 4.3
Podophyllotoxin 4.3
Pirarubicin 4.3
Purvalanol 4.3
5-Fluorouridine 4.3
Forodesine 4.3
Dyazide 4.3
Tanespimycin 4.3
Red ginseng 4.3
more...
Enzyme
zingipain 7.2
EC 1.6.2.5 7.2
L-aspartate:ammonia ligase 7.2
endoribonuclease V 6.8
TACE 6.7
phosphoglucokinase 6.5
N8-acetylspermidine deacetylase 6.5
tyrosine aminotransferase 6.4
thioether S-methyltransferase 6.3
L-asparagine synthetase 6.3
deoxyuridine phosphorylase 6.2
fumarylacetoacetate hydrolase 6.2
DNase V 6.0
glycine N-methyltransferase 5.8
N-acetylglucosaminyltransferase III 5.8
methylsterol monooxygenase 5.8
GDP-L-fucose pyrophosphorylase 5.6
N-acetylglucosaminyltransferase V 5.6
FucT 5.6
tRNA sulfurtransferase 5.5
aryl sulfotransferase IV 5.4
carboxypeptidase D 5.4
FGAM synthetase 5.4
betaine-homocysteine methyltransferase 5.3
phosphatidylethanolamine N-methyltransferase 5.1
cathepsin B-like protease 5.0
kallikrein 10 5.0
alpha-N-acetylglucosaminyl phosphodiesterase 4.9
EC 2.4.99.1 4.9
PMT 4.9
N-acetylglucosaminyltransferase IV 4.9
uridine kinase 4.9
amidophosphoribosyltransferase 4.9
methionine adenosyltransferase 4.8
glucosaminyl 3-O-sulfotransferase 4.8
glucosaminyl 3-O-sulfotransferase 4.8
triokinase 4.7
aryl hydrocarbon hydroxylase 4.6
CYP39A1 4.6
GMP synthase 4.6
dimethylglycine dehydrogenase 4.5
NADPH:quinone oxidoreductase 4.5
dihydrolipoyl transacylase 4.5
acylcarnitine hydrolase 4.4
GMP synthetase 4.4
glucose-6-phosphatase 4.4
trihydroxycoprostanoyl-CoA oxidase 4.3
matrix metalloproteinase 14 4.3
Dol-P phosphatase 4.3
pyruvate dehydrogenase phosphatase 4.3
site-1 protease 4.3
chloramphenicol acetyltransferase 4.3
nicotinamide N-methyltransferase 4.2
argininosuccinate synthetase 4.2
CYP7A1 4.2
phosphoenolpyruvate carboxykinase 4.2
HK2 4.2
phosphoenolpyruvate carboxykinase 4.2
hepsin 4.2
hepsin 4.2
gamma-glutamyl transpeptidase 4.1
conjugase 4.1
caspase-9 4.1
fatty-acid synthase 4.1
phosphoenolpyruvate carboxykinase 4.1
alpha-L-fucosidase 4.1
UDP-N-acetylglucosamine 2-epimerase 4.1
alanine aminotransferase 4.1
PLP phosphatase 4.0
acyl-CoA oxidase 4.0
alpha-L-fucosidase 4.0
dihydrodiol dehydrogenase 4.0
luciferase 4.0
galactosylhydroxylysyl glucosyltransferase 4.0
site-1 protease 4.0
HK3 4.0
sarcosine dehydrogenase 4.0
HMG-CoA synthase 4.0
NQO1 3.9
asparagine synthetase 3.9
more...
Compound
C15H24N2O 8.8
Achillin 8.8
butyl thiocyanate 8.8
tert-Butyl carbazate 8.8
C8HF15O2 8.8
10-ethyl-10H-phenothiazine 8.8
C15H24N2O 8.8
C15H20O 8.8
C16H15N3O3 8.8
2,2-dimethylpentanedioic acid 8.8
C15H24N2O 8.8
C8HF15O2 8.8
C15H20O 8.8
C15H24N2O 8.8
C15H20O 8.8
C20H21NO5 8.8
C16H15N3O3 8.8
C16H15N3O3 8.8
4,4'-Thiodianiline 8.8
C20H21NO5 8.8
C15H24N2O 8.8
C15H24N2O 8.8
C16H15N3O3 8.8
C15H24N2O 8.8
C15H20O 8.8
C15H24N2O 8.8
C15H20O 8.8
C20H21NO5 8.8
C15H20O 8.8
C15H20O 8.8
2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 8.8
C15H24N2O 8.8
C15H24N2O 8.8
C15H20O 8.8
C15H20O 8.8
C15H24N2O 8.8
C15H24N2O 8.8
C20H21NO5 8.8
C15H20O 8.8
C35H36N4O5 8.8
C16H15N3O3 8.8
C16H15N3O3 8.8
C20H21NO5 8.8
C15H24N2O 8.8
Diazoimidazole-4-carboxamide 8.8
5-Nitro-o-anisidine 8.8
C15H24N2O 8.8
C8HF15O2 8.8
C20H21NO5 8.8
C16H15N3O3 8.8
C15H20O 8.8
C8H8O5 8.5
C8H8O5 8.5
C8H8O5 8.5
C8H8O5 8.5
C8H8O5 8.5
C8H8O5 8.5
C8H8O5 8.5
C8H8O5 8.2
C8H8O5 8.2
C8H8O5 8.0
C8H8O5 8.0
2-propylpiperidine 7.8
Butrin 7.8
C14H22N2O2 7.8
2,3-dibromopropanal 7.8
C19H18O7 7.8
C18H13N5O 7.8
C23H27N3O2 7.8
C22H26N2O5 7.8
Dioncophylline A 7.8
Taccalonolide A 7.8
Meladrazine 7.8
C8H17NO2 7.8
C17H17N 7.8
C15H18N2O 7.8
C11H14O6 7.8
C15H20O 7.8
C15H20O 7.8
1-phenyl-1-nonen-3-one 7.8
more...