Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0019204 (hepatocellular carcinoma)
71,386 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 4484 Mol 4098 HCC 2985 alpha-fetoprotein 2637 p53 2197 insulin 1950 interferon 1821 surface antigen 1345 caspase-3 1273 albumin 1195 AFP 1126 Bcl-2 987 cytokine 982 AKT 928 catenin 884 endoplasmic reticulum 850 mTOR 735 IFN 714 PLC 680 PI3K 665 ATP 657 p21 651 vascular endothelial growth factor 644 ERK 641 glycoprotein 553 IL-6 553 E-cadherin 543 alanine aminotransferase 524 MRI 520 tumor necrosis factor 518 cyclin D1 513 NMR 509 TNM 509 MAPK 505 histone 469 tyrosine kinase 469 STAT3 460 TNF 456 collagen 439 p38 432 Alpha-fetoprotein 429 prothrombin 422 polypeptide 415 UTR 409 GSH 395 serum albumin 391 cytochrome c 384 ERK1 379 ras 378 cytochrome P450 377 JNK 373 CD8 365 lectin 364 interleukin-6 363 aspartate aminotransferase 346 caspase-9 342 core protein 338 alkaline phosphatase 333 microsomal 332 cytochrome 330 c-myc 327 proliferating cell nuclear antigen 326 VEGF 321 fused 318 matrix metalloproteinase 314 PARP 312 aryl hydrocarbon receptor 311 proteasome 311 ubiquitin 305 vimentin 297 ROS 294 hepatocyte growth factor 292 caspase-8 289 c-Myc 287 CD4 286 gut 278 transferrin 275 epidermal growth factor receptor 273 xenobiotic 273 MEK 272 more...

Disease hepatocellular carcinoma 71386 tumor 22326 cancer 21368 cirrhosis 11620 liver cancer 7544 hepatitis B 6923 Hepatocellular carcinoma 6346 hepatitis C 4994 liver cancer 4548 chronic hepatitis 4199 liver disease 4017 carcinoma 3232 HCC 2985 carcinogenesis 2821 tumor growth 2745 hepatitis 2526 tumorigenesis 2258 metastases 2053 chronic liver disease 1867 tumor progression 1609 virus infection 1395 breast cancer 1152 fatty liver 1130 adenocarcinoma 1107 viral hepatitis 1077 diabetes 1039 liver fibrosis 1026 obesity 1015 Nonalcoholic fatty liver 709 lung cancer 670 melanoma 655 colorectal cancer 640 leukemia 627 gastric cancer 617 arterial embolization 590 metabolic syndrome 523 adenoma 517 MCF 507 hepatoblastoma 480 portal hypertension 466 alcoholic fatty liver 458 HIV 452 colon cancer 447 acute hepatitis 435 lymphoma 418 Chronic hepatitis B 418 chronic active hepatitis 413 renal cell carcinoma 408 type 2 diabetes 397 GSH 395 liver metastases 388 prostate cancer 386 infectious diseases 373 primary tumor 371 sarcoma 364 pancreatic cancer 340 squamous cell carcinoma 319 lung carcinoma 302 hemangioma 296 alcoholic cirrhosis 280 hypertension 278 Infection 267 Chronic hepatitis C 266 hemochromatosis 253 tumor angiogenesis 249 glioma 245 alcohol abuse 245 iron overload 244 aggressiveness 243 dysplasia 243 immunodeficiency 239 Cirrhosis 238 NS3 235 SDS 225 esophageal varices 222 neuroblastoma 222 anemia 216 ovarian cancer 211 cervical cancer 211 ischemia 209 more...

Symptom pain 331 abdominal pain 316 hepatomegaly 199 starvation 183 fatigue 170 diarrhea 164 nausea 113 anorexia 105 vomiting 98 weakness 88 cachexia 86 anesthesia 83 dyspnea 75 collapse 66 overweight 63 splenomegaly 63 exhaustion 58 headache 54 Ill 47 epigastric pain 46 nausea and vomiting 45 cough 34 discomfort 32 discomfort 32 right upper quadrant pain 32 seizures 31 abdominal discomfort 30 back pain 29 chest pain 25 lethargy 22 hepatosplenomegaly 20 erythema 19 analgesia 17 abdominal fullness 17 acute abdomen 16 bone pain 16 decreased appetite 15 respiratory distress 15 shortness of breath 15 asthenia 15 hemoptysis 14 leg edema 13 arthralgia 13 constipation 13 HSA 13 myalgia 13 hypoproteinemia 12 hypothermia 12 acidity 12 numbness 12 exertional dyspnea 11 acute abdominal pain 11 ataxia 11 chills 10 flank pain 10 flushing 10 regurgitation 9 agitation 9 tremor 9 syncope 9 cancer pain 8 sleepiness 8 paresthesia 8 low back pain 8 ophthalmoplegia 8 fever of unknown origin 8 leg pain 7 dizziness 7 Spots 6 acute stress 6 cyanosis 6 stigma 6 hoarseness 5 bloating 5 hyperoxia 5 pallor 5 Wind 5 cerebellar ataxia 5 functional recovery 5 spasm 4 more...

Drug Sorafenib 818 Lipiodol 398 lysine 355 ROS 294 Adriamycin 165 Gel 151 IL-2 148 DNase I 145 Monit 137 Cardiovasc 134 IFN-gamma 133 Portal 116 vitamin E 112 ROC 106 Ethanol 97 Albumin 86 GEO 84 ascorbate 83 NADH 71 ADM 68 MAP 67 ABC 60 Gelfoam 57 Dermatol 54 caffeine 53 Glutathione 51 CSF 49 lactose 49 Arsenic trioxide 42 IFN-beta 42 Asn 40 TAT 38 Retinoic acid 37 EE2 36 CTX 36 Sonazoid 35 Vitamin K 34 G418 33 Nexavar 32 Meth 32 PCB 31 Entecavir 31 Entecavir 31 Biopolymers 31 MRC 31 Levovist 31 Heme 30 ADR 29 Paraffin 28 uPA 27 Mutagen 27 ENT 27 Kenyan 27 Leaf 26 citric acid 25 CoCl2 24 CoCl2 24 ICI 23 Serum albumin 23 CAM 23 Glycyrrhiza 22 Taxol 22 PMEA 21 Indomethacin 20 Gelatin 20 Bayer 20 AGG 19 Bevacizumab 19 IL-11 19 Vitamin A 19 Gefitinib 19 Vitamin E 19 CTX 18 CTX 18 HCH 18 CCL 17 niacin 17 Glucagon 17 ATV 17 CTA 17 more...

Enzyme mitogen-activated protein kinase 1601 ERK 1495 luciferase 1375 caspase-3 1013 alanine aminotransferase 1004 protein kinase 839 focal adhesion kinase 570 aspartate aminotransferase 556 catalase 389 glutathione S-transferase 381 MEK 360 gamma-glutamyl transpeptidase 356 reverse transcriptase 354 PARP 353 protein kinase C 341 alkaline phosphatase 334 proteasome 315 caspase-9 291 superoxide dismutase 290 AMP-activated protein kinase 281 tyrosine aminotransferase 253 lactate dehydrogenase 237 chloramphenicol acetyltransferase 225 caspase-8 224 P-glycoprotein 216 NQO1 214 RNA polymerase 210 ATPase 204 trypsin 203 AST 196 phosphoenolpyruvate carboxykinase 193 thymidine kinase 191 TACE 190 AMPK 184 peroxidase 181 phosphatidylinositol 3-kinase 177 cdc2 175 phosphoenolpyruvate carboxykinase 174 RNase 168 phosphoenolpyruvate carboxykinase 162 RNase 159 calcineurin 155 ACS 150 AMPK 147 CYP3A4 146 GSK 145 glucose-6-phosphatase 143 glutathione peroxidase 141 DNA polymerase 139 phosphoinositide 3-kinase 126 ornithine decarboxylase 116 urokinase-type plasminogen activator 116 hexokinase 108 collagenase 108 APC 108 neuraminidase 104 glutamine synthetase 103 aldehyde dehydrogenase 100 aldehyde dehydrogenase 98 aldehyde dehydrogenase 95 aldehyde dehydrogenase 95 aldehyde dehydrogenase 95 alcohol dehydrogenase 92 aryl hydrocarbon hydroxylase 92 beta-galactosidase 92 thrombin 89 transcriptase 87 arginase 84 DNA methyltransferase 81 topoisomerase 80 pyruvate kinase 79 endonuclease 76 topoisomerase 73 phospholipase C 72 IKK 69 DNase 67 acetylcholinesterase 66 ceruloplasmin 66 phosphodiesterase 65 lipase 61 more...

Compound DNA 7730 Dec 4864 Clin 3572 oxygen 1807 glucose 1344 MTT 1298 ethanol 1246 water 925 sodium 900 iron 868 tyrosine 739 methionine 664 calcium 661 ATP 657 phosphate 566 acetate 546 galactose 523 TNM 509 sulfate 496 serine 461 TNF 456 cysteine 449 PEG 447 lysine 438 GSH 429 GSH 429 Insulin 404 aflatoxin B1 403 arginine 391 bromide 365 cAMP 356 copper 330 zinc 320 PEG 318 hydrogen 312 iodine 307 leucine 304 Adriamycin 298 His 287 retinoic acid 281 pyrene 281 threonine 278 urea 277 alanine 273 AMP 269 MEK 262 5-FU 252 MDA 241 SDS 236 nitric oxide 233 Pac 218 glutamine 203 NAD 192 TACE 190 nitrogen 181 salt 180 DEN 171 ADR 169 HEP 169 N-acetylcysteine 168 ADP 167 NAD 163 H2O2 159 Phe 158 uridine 158 methanol 158 selenium 155 CAT 151 ACS 149 CAT 149 CAT 149 ACS 146 ADP 145 ADP 145 Asp 137 DTPA 136 silver 136 TOF 136 pyrimidine 136 pyrimidine 135 more...

---