Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019204 (hepatocellular carcinoma)
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Human Gene/Protein
leucine zipper and CTNNBIP1 domain containing 8.8
FLJ33360 8.8
zinc finger protein 292 8.8
PNLIPRP3 8.8
Transmembrane protein 9 8.8
Beta-actin-like protein 2 8.8
MRIP-1 8.8
hemoglobin alpha-2 8.8
Ubiquitin-conjugating enzyme E2 J2 8.8
chromosome 10 open reading frame 104 8.8
ZNF365 protein 8.8
MHC class II HLA-DQ 8.8
zinc finger protein 542 8.8
HCBP1 8.8
NHE6.1 8.8
C9orf100 8.8
LAMB1 protein 8.8
LOC100129335 8.8
non-protein coding RNA 52 8.8
Chromodomain helicase DNA binding protein 1 8.8
PSG9 protein 8.8
LRRC24 8.8
Psoriasis susceptibility 1 candidate 1 8.8
BRUNOL5 8.8
melanoma inhibitory activity 2 8.8
RecA homolog, E. coli 8.8
TIPUH1 8.8
SEC13-like 1 isoform 8.8
transmembrane protein 40 8.8
OR1L3 8.8
SPATA21 8.8
annexin IV variant 8.8
T-complex protein 10A homolog 2 8.8
Complement factor H-related 3 8.8
retinoic acid induced 16 8.8
apoptosis-inducing factor, mitochondrion-associated, 3 8.8
UCKL1 8.8
nucleolar complex associated 2 homolog 8.8
CEBPD protein 8.8
spectrin repeat containing, nuclear envelope 2 8.8
more...
Disease
Intestinal carcinoma 8.8
cystorrhagia 8.8
HCC 8.8
Hepatobiliary neoplasms 8.8
Uterine Carcinosarcoma 8.8
Acquired porphyria 8.8
Anemias due to chronic disorders 8.8
adult primary liver cancer 8.8
hepatocellular carcinoma 8.8
Cholangioma 8.8
Metastasis to adrenal gland 8.8
HC/HCC 8.8
TSG11 8.8
Hepatocellular carcinoma 8.8
Perinatal hepatitis 8.8
Intrahepatic bile duct cancer 8.8
Fibrolamellar hepatocellular carcinoma 8.5
hepatocholangiocarcinoma 8.4
HTC1 8.3
Hepatic vein occlusion 8.2
Intrahepatic biloma 8.2
Hepatocarcinogenesis 8.1
Macronodular cirrhosis 8.1
Primary liver cancer 8.0
Hepatoid adenocarcinoma 8.0
virus related cancer 7.8
Early cirrhosis 7.8
TCPT 7.8
Bile duct necrosis 7.8
Tumor hemorrhage 7.8
Hepatocellular Adenoma 7.8
liver cancer 7.8
Chronic hepatitis B 7.7
Chronic viral hepatitis 7.6
cholangioma 7.5
Kupffer cell sarcoma 7.5
liver cancer 7.5
Radiation-induced liver disease 7.3
Hereditary tyrosinemia type I 7.3
Metastasis to spleen 7.2
more...
Symptom
prickling sensation 4.9
Upper abdominal pain 4.5
right upper quadrant pain 4.4
rib pain 4.3
eye discharge 4.3
abdominal fullness 4.2
hepatomegaly 3.9
Acute dyspnea 3.8
epigastric distress 3.2
leg edema 3.1
Pain symptoms 3.0
abdominal discomfort 3.0
cachexia 2.8
intestinal angina 2.7
dark urine 2.7
abnormal breathing 2.6
Kayser-Fleischer ring 2.6
epigastric pain 2.6
Sister Mary Joseph's nodule 2.6
Spots 2.6
decreased appetite 2.5
No toxic effect 2.5
lumbar back pain 2.4
hypoproteinemia 2.2
abdominal pain 2.2
Scratch 2.2
autodigestion 2.1
localized edema 2.1
pedal edema 2.1
No adverse effect 2.1
left upper quadrant pain 1.8
anorexia 1.8
starvation 1.7
Signs and Symptoms 1.7
chromosome marker 1.7
generalized rash 1.6
voice change 1.5
splenomegaly 1.5
arm pain 1.4
frequent urination 1.4
more...
Drug
Peretinoin 8.8
Truphylline 8.8
Smancs 8.1
Sorafenib 7.9
Liskantin 7.8
Sophora root 7.8
Paulomycin 7.8
Alisma rhizome 7.8
Lipiodol 7.8
IFEX 7.2
Livact 7.2
Edotecarin 7.2
Nexavar 7.1
Monoammonium glycyrrhizinate 6.8
MK-803 6.8
18DG 6.6
Sonazoid 6.6
Mesoheme 6.5
Butyramide 6.5
Topotecan hydrochloride 6.5
Syprine 6.5
Mangafodipir trisodium 6.2
Hepatitis B immune globulin 6.1
Tesamorelin 6.0
Diammonium glycyrrhizinate 6.0
Entecavir 5.9
Entecavir 5.9
Ferumoxides 5.8
Span 65 5.8
C6F14 5.8
Thymalfasin 5.7
Levovist 5.7
Hexobendine 5.6
Bupleurum root 5.6
OKG 5.5
Radicut 5.5
Nitisinone 5.4
Scutellaria root 5.4
Parecoxib sodium 5.3
Advexin 5.3
more...
Enzyme
zingipain 7.2
EC 1.6.2.5 7.2
L-aspartate:ammonia ligase 7.2
endoribonuclease V 6.8
TACE 6.7
N8-acetylspermidine deacetylase 6.5
phosphoglucokinase 6.5
tyrosine aminotransferase 6.4
thioether S-methyltransferase 6.3
L-asparagine synthetase 6.3
deoxyuridine phosphorylase 6.2
fumarylacetoacetate hydrolase 6.2
DNase V 6.0
glycine N-methyltransferase 5.8
methylsterol monooxygenase 5.8
N-acetylglucosaminyltransferase III 5.8
GDP-L-fucose pyrophosphorylase 5.6
N-acetylglucosaminyltransferase V 5.6
FucT 5.6
tRNA sulfurtransferase 5.5
aryl sulfotransferase IV 5.4
carboxypeptidase D 5.4
FGAM synthetase 5.4
betaine-homocysteine methyltransferase 5.3
phosphatidylethanolamine N-methyltransferase 5.1
cathepsin B-like protease 5.0
kallikrein 10 5.0
alpha-N-acetylglucosaminyl phosphodiesterase 4.9
EC 2.4.99.1 4.9
PMT 4.9
uridine kinase 4.9
N-acetylglucosaminyltransferase IV 4.9
amidophosphoribosyltransferase 4.9
methionine adenosyltransferase 4.8
glucosaminyl 3-O-sulfotransferase 4.8
glucosaminyl 3-O-sulfotransferase 4.8
triokinase 4.7
aryl hydrocarbon hydroxylase 4.6
CYP39A1 4.6
GMP synthase 4.6
more...
Compound
C20H21NO5 8.8
C20H21NO5 8.8
C15H20O 8.8
C15H24N2O 8.8
butyl thiocyanate 8.8
C8HF15O2 8.8
C15H24N2O 8.8
4,4'-Thiodianiline 8.8
C20H21NO5 8.8
C20H21NO5 8.8
C15H24N2O 8.8
C15H20O 8.8
C15H20O 8.8
Achillin 8.8
C16H15N3O3 8.8
C15H24N2O 8.8
C16H15N3O3 8.8
C15H24N2O 8.8
C15H24N2O 8.8
10-ethyl-10H-phenothiazine 8.8
2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 8.8
C16H15N3O3 8.8
C15H20O 8.8
C15H20O 8.8
C15H20O 8.8
tert-Butyl carbazate 8.8
C15H24N2O 8.8
C35H36N4O5 8.8
Diazoimidazole-4-carboxamide 8.8
C16H15N3O3 8.8
C15H24N2O 8.8
C15H24N2O 8.8
C15H24N2O 8.8
C20H21NO5 8.8
C15H24N2O 8.8
C15H20O 8.8
C20H21NO5 8.8
2,2-dimethylpentanedioic acid 8.8
C16H15N3O3 8.8
C15H20O 8.8
more...