Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019204 (hepatocellular carcinoma)
71,386 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 4484
Mol 4098
HCC 2985
alpha-fetoprotein 2637
p53 2197
insulin 1950
interferon 1821
surface antigen 1345
caspase-3 1273
albumin 1195
AFP 1126
Bcl-2 987
cytokine 982
AKT 928
catenin 884
endoplasmic reticulum 850
mTOR 735
IFN 714
PLC 680
PI3K 665
ATP 657
p21 651
vascular endothelial growth factor 644
ERK 641
glycoprotein 553
IL-6 553
E-cadherin 543
alanine aminotransferase 524
MRI 520
tumor necrosis factor 518
cyclin D1 513
NMR 509
TNM 509
MAPK 505
histone 469
tyrosine kinase 469
STAT3 460
TNF 456
collagen 439
p38 432
more...
Disease
hepatocellular carcinoma 71386
tumor 22326
cancer 21368
cirrhosis 11620
liver cancer 7544
hepatitis B 6923
Hepatocellular carcinoma 6346
hepatitis C 4994
liver cancer 4548
chronic hepatitis 4199
liver disease 4017
carcinoma 3232
HCC 2985
carcinogenesis 2821
tumor growth 2745
hepatitis 2526
tumorigenesis 2258
metastases 2053
chronic liver disease 1867
tumor progression 1609
virus infection 1395
breast cancer 1152
fatty liver 1130
adenocarcinoma 1107
viral hepatitis 1077
diabetes 1039
liver fibrosis 1026
obesity 1015
Nonalcoholic fatty liver 709
lung cancer 670
melanoma 655
colorectal cancer 640
leukemia 627
gastric cancer 617
arterial embolization 590
metabolic syndrome 523
adenoma 517
MCF 507
hepatoblastoma 480
portal hypertension 466
more...
Symptom
pain 331
abdominal pain 316
hepatomegaly 199
starvation 183
fatigue 170
diarrhea 164
nausea 113
anorexia 105
vomiting 98
weakness 88
cachexia 86
anesthesia 83
dyspnea 75
collapse 66
overweight 63
splenomegaly 63
exhaustion 58
headache 54
Ill 47
epigastric pain 46
nausea and vomiting 45
cough 34
discomfort 32
discomfort 32
right upper quadrant pain 32
seizures 31
abdominal discomfort 30
back pain 29
chest pain 25
lethargy 22
hepatosplenomegaly 20
erythema 19
abdominal fullness 17
analgesia 17
acute abdomen 16
bone pain 16
decreased appetite 15
shortness of breath 15
asthenia 15
respiratory distress 15
more...
Drug
Sorafenib 818
Lipiodol 398
lysine 355
ROS 294
Adriamycin 165
Gel 151
IL-2 148
DNase I 145
Monit 137
Cardiovasc 134
IFN-gamma 133
Portal 116
vitamin E 112
ROC 106
Ethanol 97
Albumin 86
GEO 84
ascorbate 83
NADH 71
ADM 68
MAP 67
ABC 60
Gelfoam 57
Dermatol 54
caffeine 53
Glutathione 51
lactose 49
CSF 49
IFN-beta 42
Arsenic trioxide 42
Asn 40
TAT 38
Retinoic acid 37
CTX 36
EE2 36
Sonazoid 35
Vitamin K 34
G418 33
Meth 32
Nexavar 32
more...
Enzyme
mitogen-activated protein kinase 1601
ERK 1495
luciferase 1375
caspase-3 1013
alanine aminotransferase 1004
protein kinase 839
focal adhesion kinase 570
aspartate aminotransferase 556
catalase 389
glutathione S-transferase 381
MEK 360
gamma-glutamyl transpeptidase 356
reverse transcriptase 354
PARP 353
protein kinase C 341
alkaline phosphatase 334
proteasome 315
caspase-9 291
superoxide dismutase 290
AMP-activated protein kinase 281
tyrosine aminotransferase 253
lactate dehydrogenase 237
chloramphenicol acetyltransferase 225
caspase-8 224
P-glycoprotein 216
NQO1 214
RNA polymerase 210
ATPase 204
trypsin 203
AST 196
phosphoenolpyruvate carboxykinase 193
thymidine kinase 191
TACE 190
AMPK 184
peroxidase 181
phosphatidylinositol 3-kinase 177
cdc2 175
phosphoenolpyruvate carboxykinase 174
RNase 168
phosphoenolpyruvate carboxykinase 162
more...
Compound
DNA 7730
Dec 4864
Clin 3572
oxygen 1807
glucose 1344
MTT 1298
ethanol 1246
water 925
sodium 900
iron 868
tyrosine 739
methionine 664
calcium 661
ATP 657
phosphate 566
acetate 546
galactose 523
TNM 509
sulfate 496
serine 461
TNF 456
cysteine 449
PEG 447
lysine 438
GSH 429
GSH 429
Insulin 404
aflatoxin B1 403
arginine 391
bromide 365
cAMP 356
copper 330
zinc 320
PEG 318
hydrogen 312
iodine 307
leucine 304
Adriamycin 298
His 287
pyrene 281
more...