Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019204 (
hepatocellular carcinoma
)
71,386
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
4484
Mol
4098
HCC
2985
alpha-fetoprotein
2637
p53
2197
insulin
1950
interferon
1821
surface antigen
1345
caspase-3
1273
albumin
1195
AFP
1126
Bcl-2
987
cytokine
982
AKT
928
catenin
884
endoplasmic reticulum
850
mTOR
735
IFN
714
PLC
680
PI3K
665
ATP
657
p21
651
vascular endothelial growth factor
644
ERK
641
glycoprotein
553
IL-6
553
E-cadherin
543
alanine aminotransferase
524
MRI
520
tumor necrosis factor
518
cyclin D1
513
NMR
509
TNM
509
MAPK
505
histone
469
tyrosine kinase
469
STAT3
460
TNF
456
collagen
439
p38
432
more...
Disease
hepatocellular carcinoma
71386
tumor
22326
cancer
21368
cirrhosis
11620
liver cancer
7544
hepatitis B
6923
Hepatocellular carcinoma
6346
hepatitis C
4994
liver cancer
4548
chronic hepatitis
4199
liver disease
4017
carcinoma
3232
HCC
2985
carcinogenesis
2821
tumor growth
2745
hepatitis
2526
tumorigenesis
2258
metastases
2053
chronic liver disease
1867
tumor progression
1609
virus infection
1395
breast cancer
1152
fatty liver
1130
adenocarcinoma
1107
viral hepatitis
1077
diabetes
1039
liver fibrosis
1026
obesity
1015
Nonalcoholic fatty liver
709
lung cancer
670
melanoma
655
colorectal cancer
640
leukemia
627
gastric cancer
617
arterial embolization
590
metabolic syndrome
523
adenoma
517
MCF
507
hepatoblastoma
480
portal hypertension
466
more...
Symptom
pain
331
abdominal pain
316
hepatomegaly
199
starvation
183
fatigue
170
diarrhea
164
nausea
113
anorexia
105
vomiting
98
weakness
88
cachexia
86
anesthesia
83
dyspnea
75
collapse
66
overweight
63
splenomegaly
63
exhaustion
58
headache
54
Ill
47
epigastric pain
46
nausea and vomiting
45
cough
34
discomfort
32
discomfort
32
right upper quadrant pain
32
seizures
31
abdominal discomfort
30
back pain
29
chest pain
25
lethargy
22
hepatosplenomegaly
20
erythema
19
abdominal fullness
17
analgesia
17
acute abdomen
16
bone pain
16
decreased appetite
15
shortness of breath
15
asthenia
15
respiratory distress
15
more...
Drug
Sorafenib
818
Lipiodol
398
lysine
355
ROS
294
Adriamycin
165
Gel
151
IL-2
148
DNase I
145
Monit
137
Cardiovasc
134
IFN-gamma
133
Portal
116
vitamin E
112
ROC
106
Ethanol
97
Albumin
86
GEO
84
ascorbate
83
NADH
71
ADM
68
MAP
67
ABC
60
Gelfoam
57
Dermatol
54
caffeine
53
Glutathione
51
lactose
49
CSF
49
IFN-beta
42
Arsenic trioxide
42
Asn
40
TAT
38
Retinoic acid
37
CTX
36
EE2
36
Sonazoid
35
Vitamin K
34
G418
33
Meth
32
Nexavar
32
more...
Enzyme
mitogen-activated protein kinase
1601
ERK
1495
luciferase
1375
caspase-3
1013
alanine aminotransferase
1004
protein kinase
839
focal adhesion kinase
570
aspartate aminotransferase
556
catalase
389
glutathione S-transferase
381
MEK
360
gamma-glutamyl transpeptidase
356
reverse transcriptase
354
PARP
353
protein kinase C
341
alkaline phosphatase
334
proteasome
315
caspase-9
291
superoxide dismutase
290
AMP-activated protein kinase
281
tyrosine aminotransferase
253
lactate dehydrogenase
237
chloramphenicol acetyltransferase
225
caspase-8
224
P-glycoprotein
216
NQO1
214
RNA polymerase
210
ATPase
204
trypsin
203
AST
196
phosphoenolpyruvate carboxykinase
193
thymidine kinase
191
TACE
190
AMPK
184
peroxidase
181
phosphatidylinositol 3-kinase
177
cdc2
175
phosphoenolpyruvate carboxykinase
174
RNase
168
phosphoenolpyruvate carboxykinase
162
more...
Compound
DNA
7730
Dec
4864
Clin
3572
oxygen
1807
glucose
1344
MTT
1298
ethanol
1246
water
925
sodium
900
iron
868
tyrosine
739
methionine
664
calcium
661
ATP
657
phosphate
566
acetate
546
galactose
523
TNM
509
sulfate
496
serine
461
TNF
456
cysteine
449
PEG
447
lysine
438
GSH
429
GSH
429
Insulin
404
aflatoxin B1
403
arginine
391
bromide
365
cAMP
356
copper
330
zinc
320
PEG
318
hydrogen
312
iodine
307
leucine
304
Adriamycin
298
His
287
pyrene
281
more...