Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019204 (hepatocellular carcinoma)
 71,386 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hepatocellular carcinoma with bile duct invasion is rare, with a reported incidence of 3.4%. A 71-year-old man with hepatocellular carcinoma underwent radiofrequency ablation(RFA)(S6, S7, S8)and required readmission 22 months after the RFA for hepatocellular carcinoma recurrence detected by gadoxetic acid-enhanced magnetic resonance imaging. Enhanced abdominal computed tomography and magnetic resonance cholangiopancreatography revealed a tumor thrombus in a biliary branch and left adrenal gland metastases. We performed a right lobectomy and left adrenalectomy. The biliary thrombus was easily removed. Postoperative histopathological examination of the resected specimen showed a moderately differentiated hepatocellular carcinoma invading the biliary tract and the absence of viable cells in the liver tumor. The patient has shown no recurrence 6 months after the hepatectomy.
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PMID:[A Resected Case of Hepatocellular Carcinoma Recurrence with Bile Duct Tumor Thrombus after RFA]. 3238 70

A 71-year-old man with a history of smoking 1 pack of cigarettes per day for the past 53 years visited our department with chest pain, and was diagnosed as spontaneous pneumothorax. A chest computed tomography scan revealed a nodular shadow in the upper portion of the left lobe of the lung, which was found to be adenocarcinoma by transbronchial lung biopsy. A left upper lobectomy and lymphadenectomy were performed. The pathological diagnosis was a high-grade fetal lung adenocarcinoma (H-FLAC) with a hepatoid adenocarcinoma component (pT2aN0M0, pStage I B). H-FLAC comprises at least 50% fetal lung-like cells, while hepatoid adenocarcinoma comprises hepatocellular carcinoma-like cells. Following the diagnosis, adjuvant chemotherapy with uracil-tegafur was started. Although both these neoplasms are known to have a poor prognosis, no recurrences were observed at 11 months postsurgery.
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PMID:[High-grade Fetal Lung Adenocarcinoma with Hepatoid Adenocarcinoma Component]. 3313 Jul 14


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