Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019204 (hepatocellular carcinoma)
 71,386 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Fludeoxyglucose F 18 ((18)F-FDG) PET/CT has not been shown to offer additional benefit in the initial diagnosis of pancreatic cancer, but studies show benefit of (18)F-FDG PET/CT in initial staging and patient prognosis. There is evidence for (18)F-FDG PET and (18)F-FDG PET/CT in staging and prognosis of cholangiocarcinoma and gallbladder cancer. (18)F-FDG PET/CT has shown promise in staging liver malignancies by detecting extrahepatic metastasis. There is evidence supporting the ability of PET/CT in predicting prognosis in patients with hepatocellular carcinoma. Evidence is evolving for the role of (18)F-FDGPET/CT in predicting prognosis and survival in patients with colorectal liver metastasis.
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PMID:FDG PET/CT in Pancreatic and Hepatobiliary Carcinomas: Value to Patient Management and Patient Outcomes. 2609 70

Major vascular invasion is one of the worst prognostic factors of hepatocellular carcinoma (HCC). Fludeoxyglucose F 18 ((18) F-FDG) positron emission tomography/computed tomography (PET/CT) method is succesfully being used in HCC patients for the detection of particularly long-distance metastasis. Major vascular invasion is shown by radiological methods [particularly dynamic CT and/or magnetic resonance imaging (MRI)]. A male patient aged 60 years was diagnosed with HCC, according to biopsy after the detection of a mass in the liver. His medical examinations that were performed for the evaluation in terms of liver transplantation were dynamic CT and dynamic MRI; invasion in the intrahepatic branches of the portal vein and in main portal vein was also detected. PET/CT was performed to investigate the distant metastases. Moreover, diffuse (18) F-FDG uptake in the intrahepatic branches of the portal vein and in the main portal vein was observed.
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PMID:A (18)F-FDG PET/CT Screening Study of a Hepatocellular Carcinoma Patient with Diffuse (18)F-FDG Uptake into the Portal Vein and its Intrahepatic Branches. 2691 85