Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019204 (hepatocellular carcinoma)
 71,386 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The preoperative CT appearances of hepatocellular carcinoma (HCC) lesions in 232 cases were analyzed. According to the CT features in shape, outline and boundary of the tumors, the HCC was divided into 3 Types: Type I--roundish expansive growth type (REG TYPE), Type II--irregular expansive growth type (IREG TYPE), and type III--irregular infiltration growth type (IIG TYPE). Comparing different CT types with findings at laparotomy or pathological specimens, it showed that the intrahepatic tumor dissemination rates of type I, II and III were 18.6%, 37.7%, and 47.8%, respectively. The lymph node metastasis rates were 0, 7.7% and 23.1%, respectively. The portal vein tumor thrombus formation rates were 2.3%, 20.8% and 46.4%, respectively. The proportion of encapsulation (67.4%, 27.3% and 5.28%, respectively) apparently decreased from type I to type III in turn. The differences were statistically significant. From type I to III the resection rate of large sized tumor decreased, and the prognosis was from bad to worse. Survival analysis (Cox's mode) showed significant differences from type I to type III. Therefore, CT classification may be used to evaluate the gross biological behavior of HCC lesions and may be of pathological and clinical relevance.
 ...
PMID:[CT morphology of hepatocellular carcinoma lesions]. 803 45