Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019204 (
hepatocellular carcinoma
)
71,386
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Sorafenib is the standard treatment for patients with advanced
hepatocellular carcinoma
(
HCC
), although it is known to cause a variety of dermatologic adverse events.
Subcorneal pustular dermatosis
(SCPD), also known as
Sneddon-Wilkinson disease
, is a rare skin eruption that accompanies various systemic disorders and may become chronically progressive. We herein describe the case of a patient who developed SCPD after sorafenib administration. The dermatologic reaction was improved by the cessation of sorafenib and worsened by its readministration. Clinicians treating
HCC
patients with sorafenib should be aware of the possibility of SCPD.
...
PMID:Sneddon-Wilkinson disease induced by sorafenib in a patient with advanced hepatocellular carcinoma. 2578 48
