Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019204 (
hepatocellular carcinoma
)
71,386
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Cold agglutinin disease
(
CAD
) is a rare autoimmune hemolytic anemia. Although it can occur secondary to lymphoproliferative disorders and autoimmune or infectious diseases,
CAD
is rarely reported as secondary to solid tumors. We report a case of a woman aged 18 years diagnosed with a well-differentiated
hepatocellular carcinoma
of the fibrolamellar subtype, who was shown to have
CAD
also. Her general condition, including
CAD
, improved after targeted therapy with sorafenib for the
hepatocellular carcinoma
and only conservative measures for the
CAD
that consisted of avoidance of cold. In summary, although it is an extremely rare association and less common than lymphoproliferative disorders,
CAD
can be associated with solid tumors.
...
PMID:Cold agglutinin disease in fibrolamellar hepatocellular carcinoma: a rare association with a rare cancer variant. 2129 66
