Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019163 (hepatitis B)
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Human Gene/Protein
OR4F3 9.7
RecA homolog, E. coli 9.7
FLJ20850 9.7
SEC13-like 1 isoform 9.7
TNFRSF10B protein 9.7
chromosome 1 open reading frame 61 9.7
Psoriasis susceptibility 1 candidate 1 9.7
polymerase (RNA) III 9.7
KIAA0675 9.7
interleukin 28 receptor, alpha 9.7
C1orf61 protein 9.7
SH3 and multiple ankyrin repeat domains 2 isoform 2 9.7
IFITM2 protein 9.7
PreS1 binding protein 9.7
SCAN domain containing 3 9.7
spectrin repeat containing, nuclear envelope 2 9.7
OR4F17 9.7
USP37 protein 9.7
HBxAg 9.2
surface antigen 9.1
GP27 9.0
Kelch-like protein 7 8.7
CD164L2 8.7
URG7 8.7
URG11 8.7
PTPN3 protein 8.7
DHX9 protein 8.7
HACL-1 8.7
homeobox D1 8.7
XLKD1 8.7
BTBD17 8.7
SAMD4B 8.7
NEU1 protein 8.7
WDR70 8.7
HLA-B*5602 8.7
CHIMP 8.7
HBXIP 8.6
hSMC5 8.5
HLA-A protein 8.5
carboxypeptidase D 8.2
THUMPD3 8.1
G antigen 6 8.1
EIF2C4 8.1
liver-related putative tumor suppressor 8.1
MIBP1 8.1
skeletal muscle and kidney enriched inositol phosphatase 8.1
CUB and Sushi multiple domains 3 8.1
Endonexin II 8.1
down-regulator of transcription 1 8.1
Selenium binding protein 1 8.1
TDRD4 8.1
KIAA0304 8.1
ZNF205 8.1
ZNF479 8.1
superkiller viralicidic activity 2-like 8.1
NTCP 8.1
gamma2-adaptin 7.9
Forkhead box F2 7.7
Schlafen family member 11 7.7
E4F1 protein 7.7
CCDC12 7.7
AP-1 complex subunit mu-1 7.7
HLA-DRw14 7.7
pregnancy-specific beta-1-glycoprotein 4 7.7
SERINC1 7.7
FERM domain containing 5 7.7
GTP-binding protein 1 7.7
CCDC91 7.7
LPRP 7.7
CDC37L1 7.7
Kelch-like protein 12 7.7
LH-B 7.7
KLHL35 7.7
BRF-2 7.7
CNKSR1 7.7
C7orf59 7.7
DEPDC6 7.7
scavenger receptor class A, member 5 7.7
DEP domain containing 5 7.7
platelet-derived growth factor beta polypeptide 7.7
more...
Disease
Viral vasculitis 9.7
Non-A, non-B, non-C hepatitis 9.7
hepatitis B 9.7
Fulminant hepatitis B 9.7
Syphilitic synovitis 9.7
Neonatal hepatobiliary disorders 9.7
Other viral diseases 9.7
Hepatitis D infection 9.7
Other hepatitis 9.5
Hepatitis B reactivation 9.4
hepatitis D 9.1
Chronic active hepatitis B 9.1
Acute hepatitis B 8.7
Australia antigen positive 8.7
Panarteritis 8.7
parasitic and fungal disease 8.7
virus related cancer 8.7
Acute uveitis 8.7
CNS abscess 8.7
Subacute hepatic failure 8.7
Rubella arthritis 8.7
Hepatitis viral infections 8.7
Bantu siderosis 8.7
Anogenital herpes 8.7
Hepatitis F 8.7
Rampant dental caries 8.7
Hepatobiliary neoplasms 8.7
Acute peptic ulcer 8.7
Chronic viral hepatitis 8.7
Chronic hepatitis B 8.6
B virus infection 8.4
Acute viral hepatitis 8.2
Gianotti-Crosti syndrome 8.2
HHT4 8.1
Cytolytic hepatitis 8.1
Chronic progressive multiple sclerosis 8.1
CPD2 8.1
noninfectious hepatitis 8.1
Chronic infection 7.8
chronic hepatitis 7.8
acute hepatitis 7.8
viral hepatitis 7.7
Cardiac cirrhosis 7.7
Advanced chronic liver disease 7.7
chronic persistent hepatitis 7.7
HCV coinfection 7.6
posttransfusion hepatitis 7.6
hepatitis A 7.6
Acute hepatitis A 7.5
chronic active hepatitis 7.5
Theiler's disease 7.5
hepatitis G 7.5
Hantavirus nephropathy 7.4
Pigmented purpuric dermatosis 7.4
Erythema nodosum migrans 7.4
Macronodular cirrhosis 7.4
drug snorting 7.4
hepatitis 7.3
Essential mixed cryoglobulinemia 7.2
Primary liver cancer 7.1
infectious hepatitis 7.1
Other infectious diseases 7.1
Seronegative arthritis 7.1
hepatitis C 7.1
Fulminant hepatitis 6.9
pediatric liver cancer 6.9
liver failure with encephalopathy 6.9
gonococcal vaginitis 6.9
myocardosis 6.9
Cryoglobulinemic glomerulonephritis 6.9
T Cell Leukemia 6.9
liver infection 6.9
chronic liver disease 6.8
viral carcinogenesis 6.7
Necrotizing vasculitis 6.7
Acute upper respiratory tract infection 6.7
Polyclonal gammopathy 6.7
Cryptogenic cirrhosis 6.7
Chlamydial cervicitis 6.7
IPV 6.6
more...
Symptom
left carotid bruit 7.7
Hemorrhagic ascites 6.7
Injection site pain 6.4
Local swelling 6.0
febricula 5.8
Local reaction 5.5
Upper abdominal pain 5.4
Sore 4.9
localized erythema 4.7
breast hyperplasia 4.6
pedal edema 4.3
Urticarial vasculitis 4.2
Darier's sign 4.1
Livedoid 4.1
dark urine 3.9
Organ failure 3.7
hepatomegaly 3.6
Catch 3.5
right upper quadrant pain 3.5
testicular pain 3.3
Flare 3.2
abdominal fullness 3.0
BHS 3.0
monoplegia 2.9
polymyalgia 2.9
livedo 2.8
leg edema 2.6
splenomegaly 2.6
Signs and Symptoms 2.6
lassitude 2.6
generalized rash 2.5
Muscle soreness 2.5
urethral discharge 2.5
night sweats 2.3
Tenderness 2.1
asthenia 2.1
Gastrointestinal symptoms 2.1
exhaustion 2.0
arthralgia 2.0
asterixis 2.0
Cushingoid 2.0
Ill 1.9
Cushingoid 1.9
myalgia 1.9
CSR 1.8
hepatosplenomegaly 1.8
aphonia 1.8
periorbital edema 1.7
emaciation 1.7
renal colic 1.6
HSA 1.6
hypoproteinemia 1.6
epigastric pain 1.5
pleuritic chest pain 1.5
clubbing 1.5
hyperemesis 1.5
oliguria 1.4
stigma 1.4
No adverse effect 1.4
Physical findings 1.3
meningism 1.3
forgetfulness 1.3
abdominal pain 1.3
bone pain 1.3
chills 1.2
anorexia 1.2
irregular bleeding 1.1
sore throat 1.1
erythema 1.1
consciousness disturbance 1.0
fever of unknown origin 1.0
tingling 1.0
abdominal discomfort 0.9
shortness of breath 0.9
Spots 0.9
orthopnea 0.9
nausea 0.9
DNA marker 0.8
lethargy 0.8
fatigue 0.7
more...
Drug
Denibulin hydrochloride 9.7
Apilimod mesylate 9.7
Tolevamer potassium sodium 9.7
Lapuleucel-T 9.7
Engerix-B 9.6
Hepatitis B immune globulin 9.5
Telbivudine 9.1
Entecavir 9.0
Entecavir 9.0
Clevudine 8.9
Adefovir dipivoxil 8.9
Linaclotide acetate 8.7
Fialuridine 8.7
Bimmugen 8.7
Esomeprazole sodium 8.7
Actimmune 8.1
Eltrombopag olamine 8.1
Belotecan hydrochloride 8.1
C20H26O3 8.1
Tenofovir disoproxil fumarate 8.0
Binodenoson 7.7
Canfosfamide hydrochloride 7.7
Propagermanium 7.7
Parotin 7.7
Thymalfasin 7.6
Epivir 7.4
Conivaptan hydrochloride 7.4
Peretinoin 7.4
Enzastaurin hydrochloride 7.4
Tenofovir 7.3
PMEA 7.1
Veldona 7.1
Icatibant acetate 7.1
Becatecarin 7.1
Lumiliximab 7.1
PMPA 7.1
Mecasermin rinfabate 6.9
Sugammadex sodium 6.9
Invanz 6.9
Lobucavir 6.9
Methylnaltrexone bromide 6.9
Apaziquone 6.9
Cianidanol 6.8
Peginterferon alfa-2b 6.8
Peginterferon alfa-2b 6.8
Pazopanib hydrochloride 6.7
Escitalopram oxalate 6.6
Focalin 6.5
Alovudine 6.5
Lonafarnib 6.5
Immune globulin 6.4
Darifenacin hydrobromide 6.4
Duloxetine hydrochloride 6.4
Atomoxetine hydrochloride 6.4
FCV 6.3
Truvada 6.3
Vernakalant hydrochloride 6.2
Menotropins 6.2
Parecoxib sodium 6.2
Yellow fever vaccine 6.2
Wellferon 6.2
Pemetrexed disodium 6.2
Sorivudine 6.1
Loxoribine 6.1
Aliskiren fumarate 6.1
Mononine 6.1
Zotarolimus 6.0
Dapoxetine hydrochloride 6.0
Docosanol 6.0
Lutropin alfa 6.0
Oxycontin 6.0
Pegasys 6.0
Atazanavir sulfate 5.9
Japanese encephalitis vaccine 5.9
Ocrelizumab 5.9
Alvocidib 5.9
Fomivirsen 5.9
Truvada 5.9
Rabies vaccine 5.8
Pitavastatin calcium 5.8
more...
Enzyme
carboxypeptidase D 8.0
endoribonuclease V 7.7
Metallocarboxypeptidase D 6.4
GMT 6.2
alanine aminotransferase 5.8
glucosaminyl 3-O-sulfotransferase 5.7
glucosaminyl 3-O-sulfotransferase 5.7
trans-N-deoxyribosylase 5.4
LDT 5.1
HK3 4.9
deoxycytidine deaminase 4.9
DNA polymerase 4.7
AST 4.5
RNase H 4.4
protein N-myristoyltransferase 4.2
cytidine deaminase 4.2
CMP-Neu5Ac hydroxylase 4.1
aspartate aminotransferase 4.1
dihydroxyacetone-phosphate acyltransferase 4.1
RPH 4.0
reverse transcriptase 4.0
NAT 3.9
UDP-N-acetylglucosamine pyrophosphorylase 3.9
deoxycytidine kinase 3.8
phosphoinositide 5-phosphatase 3.8
poly(A)-specific ribonuclease 3.8
TACE 3.8
glycine decarboxylase 3.7
AGT 3.7
deoxyguanosine kinase 3.5
leishmanolysin 3.5
IOR 3.5
poly(A)-specific ribonuclease 3.4
exonuclease V 3.3
chloramphenicol acetyltransferase 3.3
glycerophosphodiester phosphodiesterase 3.3
EC 2.4.99.1 3.3
matrix metalloproteinase 14 3.2
pyruvate dehydrogenase phosphatase 3.2
CYP8B1 3.2
polypeptide N-acetylgalactosaminyltransferase 3.2
AFR 3.1
mannosidase I 3.0
LMT 2.9
type III procollagen 2.8
gamma-glutamyl transpeptidase 2.8
alcohol oxidase 2.7
AOR 2.7
dynein ATPase 2.7
ADH3 2.7
carboxypeptidase E 2.6
phosphoserine phosphatase 2.6
SRR 2.6
CDR 2.6
7-dehydrocholesterol reductase 2.5
fumarylacetoacetate hydrolase 2.5
hepsin 2.5
hepsin 2.5
arachidonate 5-lipoxygenase 2.5
D-amino-acid oxidase 2.5
thymidine kinase 2.5
fatty-acid synthase 2.4
inosine triphosphatase 2.4
factor C 2.4
microsomal epoxide hydrolase 2.4
transcriptase 2.3
alpha-L-fucosidase 2.3
DD-carboxypeptidase 2.3
proteinase-3 2.3
alpha-L-fucosidase 2.3
GCA 2.3
dCMP deaminase 2.2
BMT 2.2
NAO 2.2
homogentisate 1,2-dioxygenase 2.1
phosphoglyceromutase 2.1
focal adhesion kinase 2.1
methionine synthase reductase 2.0
S1 nuclease 2.0
proteinase K 2.0
more...
Compound
(2,2-dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate 9.7
2-Amino-6-chloropurine 9.7
Robustaflavone 9.7
octanohydrazide 9.1
C6H13NO3 8.1
3TC 8.0
C8H11N 7.7
Berberine iodide 7.7
Cinobufotalin 7.7
Propagermanium 7.5
PMEA 7.5
Mulberrofuran G 7.4
HBC 7.4
Emtricitabine 7.3
Aristeromycin 7.2
Bullatacin 7.0
Allopurinol riboside 6.9
Allopurinol riboside 6.9
Allopurinol riboside 6.9
(2,2-dimethyl-1,3-dioxolan-4-yl)methyl 6.9
Allopurinol riboside 6.9
ara-AMP 6.8
ara-AMP 6.8
Oxycodone hydrochloride 6.7
Plumieride 6.7
Destruxin B 6.7
Pelentan 6.7
A 435 6.5
PHPS 6.5
isonicotinoyl chloride 6.5
Ditan 6.5
DTP 6.5
Penciclovir 6.5
Rubiadin 6.4
Vidarabine 6.4
Interferon alfa-2a 6.3
Adenine arabinoside 6.3
Diazoaminobenzene 6.2
Ara-A 6.2
DNAP 6.1
HM-5 6.1
ARA-AMP 6.1
THPA 5.9
p-Hydroxyacetophenone 5.9
Berol 5.8
Bullatacin 5.8
2-Aminopurine 5.7
Abbott 5.6
Ricinine 5.5
CPH 5.5
Taraxasterol 5.4
SLEX 5.3
DIBA 5.3
C6H8O4 5.2
DPT 5.2
Dioxolane 5.1
2-octynoic acid 5.1
aflatoxin B1 5.0
238A 5.0
Oxymatrine 5.0
I acid 5.0
MIBT 5.0
Nosiheptide 5.0
Arctiin 4.9
2-piperidinone 4.8
Sudafed 4.8
Alum 4.8
S.T.D. 4.7
IDU 4.7
Sudafed 4.7
Anisole 4.6
NMHE 4.5
2-iodoethyl 4.5
C16H14O4 4.5
Organon 4.4
2-indanol 4.4
SHB 4.4
BPL 4.4
cephalotaxine 4.3
Stearylamine 4.3
more...