Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019163 (hepatitis B)
 38,309 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
surface antigen 8232
Sep 2485
interferon 1870
alanine aminotransferase 1070
Mol 893
IFN 665
cytokine 585
core protein 570
CD4 549
DNA polymerase 485
alpha-fetoprotein 458
polypeptide 447
p53 389
Gen 386
CD8 384
albumin 368
aspartate aminotransferase 300
HLA 294
interferon-alpha 293
envelope protein 276
HCC 252
endoplasmic reticulum 244
serum albumin 239
fused 235
IFN-gamma 196
S protein 193
kit 182
STD 177
She 173
interferon alpha 170
prothrombin 169
AST 168
tumor necrosis factor 165
TNF 164
alkaline phosphatase 160
IgA 157
NTCP 151
PLC 143
IL-10 140
IL-2 138
insulin 135
glycoprotein 131
lymphoid 128
peroxidase 114
IL-4 113
interferon-gamma 112
AFP 111
PEG 107
B19 106
IL-6 101
Pol 100
human leukocyte antigen 97
JAMA 96
transactivator 94
non-Hodgkin's lymphoma 93
SDS 91
MHC 90
factor VIII 89
hemoglobin 88
rheumatoid factor 87
interleukin-2 86
anonymous 85
Polymerase 85
chronic renal failure 84
proteasome 84
San 84
NMR 82
major histocompatibility complex 81
Alpha-fetoprotein 79
Cytokine 78
p21 77
HLA-A2 76
ras 75
pol 75
ferritin 73
hemochromatosis 73
collagen 68
HLA-DR 67
lipopolysaccharide 67
interleukin-6 65
mer 65
tumor necrosis factor alpha 64
Mem 63
TNF-alpha 63
HLA class I 62
chemokine 62
ubiquitin 62
CD20 61
ACS 61
Fas 60
RIN 59
interacting protein 59
catenin 59
AP-1 59
TDF 57
MHC class I 57
CD25 57
c-myc 57
RNase H 57
HLA class II 55
dimeric 54
histone 53
fibrinogen 52
interferon gamma 52
DR1 51
ATP 51
AKT 50
Men 50
gut 50
MMR 49
MRI 49
thymidine kinase 49
lectin 49
P protein 49
ABO 48
Alanine aminotransferase 48
Sp1 46
IL-17 46
C-reactive protein 46
EPI 46
caspase-3 45
GST 45
MAPK 45
mTOR 44
CD86 44
PD-1 43
STAT 43
UTR 43
IL-8 42
Bcl-2 42
carcinoembryonic antigen 42
membrane protein 41
PI3K 41
HLA-A 41
glutathione S-transferase 41
T cell receptor 41
p24 40
p65 40
ORF 40
membrane-bound 39
IgE 39
SARS 39
TLR4 39
HBxAg 39
heavy chain 38
c-Jun 38
hemophilia A 38
MHC class II 37
threonine 37
IgG3 37
CBT 37
ERK 37
TNM 37
cage 36
GM-CSF 36
protease inhibitor 36
JNK 36
endonuclease 36
cytochrome P450 36
E-cadherin 35
more...
Disease
hepatitis B 38309
hepatocellular carcinoma 6923
hepatitis 5612
hepatitis C 5527
chronic hepatitis 5356
cirrhosis 4510
HIV 3238
cancer 2937
virus infection 2929
liver disease 2658
immunodeficiency 2333
viral hepatitis 1989
tumor 1900
hepatitis A 1528
liver cancer 1391
acute hepatitis 1377
infectious diseases 1362
AIDS 1233
chronic liver disease 1175
liver cancer 1120
chronic active hepatitis 846
tetanus 735
influenza 730
cytomegalovirus 715
Hepatocellular carcinoma 711
hepatitis D 679
viremia 640
syphilis 587
Infection 576
diphtheria 568
tuberculosis 538
carcinogenesis 537
measles 520
pertussis 503
Epstein 488
rubella 458
diabetes 430
Chronic hepatitis B 425
polio 422
varicella 393
herpes simplex 384
STD 364
liver fibrosis 353
carcinoma 352
Haemophilus 336
West 325
mumps 319
tumorigenesis 314
malaria 280
lymphoma 275
B virus infection 268
chronic persistent hepatitis 265
HCC 252
vasculitis 248
hepatitis E 247
fatty liver 237
glomerulonephritis 236
renal disease 230
leukemia 224
obesity 222
Chronic infection 199
polyarteritis nodosa 195
herpes 193
membranous nephropathy 176
primary biliary cirrhosis 169
alcohol abuse 162
haemophilia 159
hypertension 154
rheumatoid arthritis 151
alcoholic cirrhosis 148
vaccinia 147
Kaposi's sarcoma 139
nephrotic syndrome 139
renal failure 139
drug abuse 136
Infections 134
systemic lupus erythematosus 134
sepsis 131
parvovirus 130
schistosomiasis 129
chronic renal failure 126
proteinuria 124
hepatitis G 124
anemia 124
hepatoblastoma 124
alcoholism 123
Cirrhosis 122
tumor growth 121
gonococcal 120
yellow fever 117
metastases 115
rabies 112
breast cancer 111
portal hypertension 110
cold 110
non-Hodgkin's lymphoma 108
EIA 107
sepsis 106
pneumonia 106
tumor progression 105
depression 103
cholestasis 102
hemochromatosis 102
Hodgkin's disease 102
chronic disease 97
arthritis 96
cryoglobulinemia 96
cervical cancer 95
Mycobacterium 95
thalassemia 95
dengue 94
alcoholic fatty liver 93
encephalopathy 93
SDS 92
Chlamydia 92
thrombocytopenia 91
smallpox 88
human papilloma virus 88
human papilloma virus 88
multiple sclerosis 88
lymphadenopathy 88
HCV coinfection 86
hepatic encephalopathy 86
Haemophilia 86
B-cell lymphoma 82
esophageal varices 82
typhoid 81
metabolic syndrome 81
cholera 79
inflammatory bowel disease 76
multiple myeloma 76
Down syndrome 75
Poland 75
dysplasia 73
IPV 71
herpes zoster 70
lupus 69
melanoma 67
Best 67
autoimmune disease 66
papilloma 64
malnutrition 63
iron overload 63
posttransfusion hepatitis 62
type 2 diabetes 61
SARS 61
rash 61
Wilson's disease 60
graft-versus-host disease 60
drug addiction 59
primary sclerosing cholangitis 58
asthma 58
gastric cancer 57
immunopathology 56
infectious hepatitis 55
toxoplasmosis 54
alcoholic hepatitis 52
purpura 52
renal insufficiency 52
leprosy 52
more...
Symptom
pain 150
fatigue 103
abdominal pain 91
diarrhea 88
hepatomegaly 85
splenomegaly 73
exhaustion 67
weakness 55
nausea 51
Ill 50
vomiting 45
headache 43
stigma 42
anorexia 37
anesthesia 35
arthralgia 35
erythema 33
seizures 32
myalgia 29
overweight 28
discomfort 23
discomfort 23
cough 22
hepatosplenomegaly 19
starvation 17
agitation 15
asthenia 14
dyspnea 13
shortness of breath 12
chills 12
epigastric pain 12
lethargy 12
back pain 11
HSA 11
collapse 10
ataxia 10
bone pain 9
right upper quadrant pain 9
dizziness 9
paresthesia 8
night sweats 7
tinnitus 7
livedo 7
sore throat 7
chest pain 7
numbness 7
sleepiness 7
respiratory distress 7
Catch 7
insomnia 6
cachexia 6
nausea and vomiting 6
cerebellar ataxia 6
constipation 6
paresis 6
oliguria 6
hemoptysis 6
fever of unknown origin 5
leg edema 5
acidity 5
paraparesis 5
pedal edema 5
dark urine 5
dysarthria 5
exertional dyspnea 5
abdominal fullness 4
ENT 4
apathy 4
hoarseness 4
testicular pain 4
hypoproteinemia 4
emaciation 4
abdominal discomfort 4
tremor 4
dysuria 3
regurgitation 3
thinning 3
acute abdomen 3
vertigo 3
tingling 3
hemiplegia 3
CSR 3
photophobia 3
Gastrointestinal symptoms 3
tense 3
renal colic 3
low back pain 3
clubbing 3
syncope 3
colic 3
pelvic pain 3
flushing 2
analgesia 2
flank pain 2
hip pain 2
shoulder pain 2
pleuritic chest pain 2
urethral discharge 2
physical appearance 2
Depressive symptoms 2
consciousness disturbance 2
skin irritation 2
lassitude 2
angina 2
DNA marker 2
Tenderness 2
decreased appetite 2
dry skin 2
Injection site pain 2
productive cough 2
hypothermia 2
forgetfulness 2
Flare 2
spasticity 2
febricula 1
acute abdominal pain 1
Muscle soreness 1
Spots 1
memory loss 1
localized erythema 1
sciatica 1
dry eye 1
Sore 1
Hudson 1
periorbital edema 1
BHS 1
generalized rash 1
distraction 1
acute pain 1
Hemorrhagic ascites 1
Cushingoid 1
chest tightness 1
Urticarial vasculitis 1
neuralgia 1
incoordination 1
hunger 1
hyperesthesia 1
polydipsia 1
neck pain 1
orthopnea 1
eds 1
sneezing 1
monoplegia 1
persistent cough 1
nasal congestion 1
limb pain 1
general problem 1
chorea 1
Signs and Symptoms 1
chronic constipation 1
clonus 1
asterixis 1
No adverse effect 1
polymyalgia 1
nasal discharge 1
Local swelling 1
pallor 1
neurological disability 1
Decreased activity 1
stridor 1
more...
Drug
IFN-gamma 194
Dermatol 148
Entecavir 139
Entecavir 139
IL-2 138
PMPA 129
PMEA 125
Engerix-B 98
lysine 94
Tenofovir 75
Adefovir dipivoxil 68
Dial 64
Nephron 53
ENT 53
Tenofovir disoproxil fumarate 53
Nephron 52
Telbivudine 52
EE2 51
CSF 47
EPI 46
Asn 36
Rituximab 36
Sorafenib 35
AZT 31
AZT 31
Monit 30
DNase I 29
Gel 28
Hepatitis B immune globulin 23
FCV 22
ROC 22
Alliance 20
Prednisolone 20
Dakar 20
IFN-beta 19
Epivir 18
Bayer 16
Albumin 16
Portal 15
AGG 14
ROS 14
BCG vaccine 14
Clevudine 13
Truvada 13
Kenyan 13
Alanine 13
HPMPC 11
PTC 11
G418 11
Asthma 11
Leaf 11
ABC 11
uPA 11
Cardiovasc 10
Immune globulin 10
Norplant 9
MAP 9
Ganciclovir 9
Biopolymers 9
Tacrolimus 9
PFA 9
CCL 8
CTM 8
Tetanus toxoid 8
Truvada 8
Methylprednisolone 8
HCH 8
Prednisone 8
-deoxyadenosine 8
Paraffin 8
Acyclovir 8
Campath 8
Campath 8
CTX 8
G-CSF 8
Swertia 8
Intron A 7
Nitazoxanide 7
Glutathione 7
Infliximab 7
Infliximab 7
Bifidobacterium 7
MRC 7
CTM 7
Serum albumin 7
AHF 7
Intron A 7
caffeine 7
Pegasys 7
Cidofovir 7
ampicillin 6
Bortezomib 6
TAT 6
ATV 6
Fialuridine 6
Ethanol 6
Adriamycin 6
vitamin E 6
VCR 6
Glycyrrhiza 6
Tuberculin 6
Adalimumab 5
p75 5
ascorbate 5
PCP 5
Ara-A 5
Tocilizumab 5
PTH 5
Abatacept 5
Japanese encephalitis vaccine 5
Intron A 5
Heme 5
ADM 5
Dasatinib 5
Epoetin 5
Denosumab 5
Bevacizumab 5
ddI 5
Ezetimibe 4
Vitamin E 4
Thymalfasin 4
Sunitinib malate 4
Fludarabine 4
Cetuximab 4
Darbepoetin alfa 4
Isoniazid 4
Everolimus 4
Pregabalin 4
Parkin 4
Escitalopram oxalate 4
GEO 4
Maraviroc 4
Vitamin A 4
Vitamin K 4
NVP 4
OMP 4
Parkin 4
Aztec 4
Gamma globulin 4
Gefitinib 4
Lonafarnib 4
Doxycycline 4
Wellferon 4
Darunavir 4
Gleevec 4
Ciclesonide 3
Hypaque 3
Ocrelizumab 3
Fragment 3
Thymopentin 3
Pimecrolimus 3
Calcipotriol 3
Yellow fever vaccine 3
Mutagen 3
NADH 3
Check 3
Ddc 3
Fraction 3
Pemetrexed disodium 3
lactose 3
more...
Enzyme
alanine aminotransferase 1775
reverse transcriptase 611
DNA polymerase 514
aspartate aminotransferase 452
focal adhesion kinase 222
AST 168
alkaline phosphatase 160
peroxidase 149
mitogen-activated protein kinase 147
luciferase 122
RNA polymerase 114
protein kinase 101
ERK 96
proteasome 86
glutathione S-transferase 83
gamma-glutamyl transpeptidase 77
RNase H 70
ACS 61
chloramphenicol acetyltransferase 59
transcriptase 57
beta-galactosidase 55
trypsin 52
thymidine kinase 50
RNase 47
protein kinase C 45
catalase 43
RNase 42
APC 37
lactate dehydrogenase 36
endonuclease 36
caspase-3 31
GMT 29
neuraminidase 28
GSK 27
calcineurin 26
DNase 24
urokinase-type plasminogen activator 24
creatine kinase 23
ATPase 23
superoxide dismutase 23
glyceraldehyde-3-phosphate dehydrogenase 22
thrombin 22
IKK 21
cytidine deaminase 21
glyceraldehyde-3-phosphate dehydrogenase 21
glyceraldehyde-3-phosphate dehydrogenase 20
glyceraldehyde-3-phosphate dehydrogenase 20
glyceraldehyde-3-phosphate dehydrogenase 20
proteinase K 20
carboxypeptidase D 19
cholinesterase 19
thromboplastin 19
acetylcholinesterase 18
CDR 18
S1 nuclease 18
MEK 16
phosphatidylinositol 3-kinase 16
pepsin 16
collagenase 15
BMT 15
deaminase 15
ceruloplasmin 14
glutathione peroxidase 14
dihydrofolate reductase 14
granzyme B 14
PARP 14
AOR 14
adenosine deaminase 13
chymotrypsin 13
caspase-9 13
CYP3A4 13
TACE 13
adenosine deaminase 13
cdc2 13
DNA methyltransferase 13
deoxycytidine kinase 12
acid phosphatase 12
lysozyme 12
furin 12
NAT 12
phosphodiesterase 12
AGT 12
ribonuclease 11
ribonuclease 11
caspase-8 11
phosphoinositide 3-kinase 11
topoisomerase 11
topoisomerase 11
CD10 11
renin 11
ACE 11
aldehyde dehydrogenase 10
lipase 10
AMP-activated protein kinase 9
glycine decarboxylase 9
firefly luciferase 9
aldehyde dehydrogenase 8
aldehyde dehydrogenase 8
aldehyde dehydrogenase 8
aldehyde dehydrogenase 8
UDP-glucuronosyltransferase 8
alpha-glucosidase 8
transpeptidase 7
glutamine synthetase 7
xanthine oxidase 7
MIP 7
MDP 7
MAP 7
cathepsin B 6
MMP 6
PNGase F 6
TAT 6
caspase-1 6
alcohol dehydrogenase 6
beta-lactamase 6
tissue plasminogen activator 6
alcohol oxidase 6
MEKK1 6
type III procollagen 6
glucose-6-phosphatase 6
subtilisin 6
micrococcal nuclease 6
LDT 5
enolase 5
NO synthase 5
arginase 5
PCP 5
microsomal epoxide hydrolase 5
AMPK 5
MMP-3 5
heparinase 4
phosphoglycerate kinase 4
factor C 4
SPC 4
PRE 4
prolyl hydroxylase 4
thyroid peroxidase 4
MDR 4
alpha-mannosidase 4
GCA 4
plasmin 4
phospholipase A2 4
glucose oxidase 4
IMP dehydrogenase 4
AMPK 4
indoleamine 2,3-dioxygenase 4
phosphoenolpyruvate carboxykinase 4
Pla 4
succinate dehydrogenase 4
C3 convertase 4
glucose-6-phosphate dehydrogenase 4
pyruvate dehydrogenase 4
polo-like kinase 1 4
RNase P 4
papain 4
adenylate cyclase 3
elastase 3
MAT 3
transglutaminase 3
urease 3
more...
Compound
DNA 8490
Clin 2770
Dec 2691
3TC 490
sodium 317
water 239
alanine 237
ethanol 229
Abbott 226
arginine 202
aflatoxin B1 185
His 177
PEG 173
TNF 164
creatinine 164
phosphate 164
glucose 150
methionine 146
oxygen 144
iron 140
tyrosine 134
serine 122
lysine 120
PEG 119
PMEA 110
cysteine 108
sulfate 107
Pac 104
leucine 104
calcium 104
aluminum 100
SDS 97
threonine 83
urea 82
galactose 80
Ile 72
salt 72
BCG 68
Dial 66
hydroxide 63
ACS 62
ACS 61
Asp 59
acetate 59
tryptophan 55
hydrogen 54
ATP 51
nitrogen 50
Phe 50
HBC 50
DTP 49
Gly 46
proline 46
PMA 46
6-12 46
zinc 45
MTT 44
bromide 44
silver 44
ammonium 43
tryptophan 42
copper 41
COS 41
tryptophan 40
AZT 40
tryptophan 40
pyrimidine 40
pyrimidine 40
isoleucine 39
isoleucine 39
formaldehyde 37
valine 37
aldehyde 37
TNM 37
nitric oxide 34
TOF 33
methanol 32
NH2 32
GPT 32
aldehyde 31
vitamin D 30
Optimal 30
AMP 30
potassium 29
DPT 29
glutamine 29
CAT 29
CAT 28
asparagine 28
aspartic acid 28
CAT 28
Ribavirin 28
Guo 27
Guo 27
hyaluronic acid 25
glutamic acid 25
iodine 25
mercury 25
formaldehyde 25
EDTA 24
Sodium 24
DMSO 24
ammonia 23
aspartic acid 23
selenium 23
vinyl 23
EDTA 23
TTP 23
aspartic acid 23
aspartic acid 23
ANCA 23
glycerol 22
Parenteral 22
Wellcome 21
GTP 21
Ara-A 21
DEAE 21
chloroform 21
cAMP 20
FK506 20
phenol 20
retinol 20
retinoic acid 20
Prednisolone 20
GSH 19
uridine 19
dCTP 19
GSH 19
silicon 18
NKT 18
Panam 17
Alum 17
SET 17
ANA 16
barium 16
Triton X-100 16
Insulin 16
phosphorus 16
TEM 16
dUTP 16
dGTP 16
ANA 16
cGMP 15
CAM 15
Emtricitabine 15
HCl 15
2-mercaptoethanol 15
acetic acid 15
ALP 15
Organon 15
THP 14
PAN 14
Primatol 14
THP 14
CPH 14
PPD 14
PAP 14
Primatol 14
Primatol 14
MSM 14
more...