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Query: UMLS:C0019158 (hepatitis)
 30,205 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The examination of needle biopsy of the liver has permitted the identification of the aetiology of cholestatic jaundice in eighty five cases out of a series of one hundred-and-one patients, leaving eight without definite diagnosis and eight false diagnosis. The characteristic histopathologic lesions of lobular hepatitis and of obstructive jaundice are reviewed. The problems of identification of particular microscopic forms (obstructive jaundice with minimal portal tracts alterations, residual stage of hepatitis, cholangiolitic and hypercholestatic forms of hepatitis) are discussed.
Sem Hop
PMID:[The value of needle biopsy of the liver in the differential diagnosis of cholestatic jaundice. A clinico-pathologic study of 101 cases (author's transl)]. 21 19

Significant percentages of patients suffering from non-A non-B hepatitis (43%) and B hepatitis (35%) were found to release an Ig-binding factor in their stools. This factor, which we called "protein F" was less frequently observed (20%) in patients suffering from other liver disorders, and was found in only 6.7% of healthy subjects (p less than 10(-7), less than 10(-4), and less than 0.03, respectively). The specificity of the detection test (a nonimmune ELISA-like assay) was confirmed by inhibition experiments. Binding was located on the F(ab) fragment of Ig, irrespectively of their isotype. Protein F was inactivated by pepsin, neuraminidase, and high concentrations of subtilisin, whereas it was resistant to trypsin and chymotrypsin. Molecular sieving by HPLC indicated an apparent molecular mass of 175 kDa. In preparative SDS-PAGE, the molecular mass was 85 kDa in favor of a dimer disrupted under dissociating conditions. Preparative IEF showed the isoelectric charge to lie between 3.9 and 4.1. Analysis of liver extracts from two patients suffering fron non-A non-B hepatitis, and from a transplant donor, revealed the presence of the factor in the three cases.
 ...
PMID:Protein F. A novel F(ab)-binding factor, present in normal liver, and largely released in the digestive tract during hepatitis. 224 21

Typhoid fever is always endemic in Ivory Coast. Among the various visceral injuries able to arrive during the course of the illness, a study of hepatic manifestations realized in 279 patients show, by the realization of systematic LBP, that, beside clinically and/or biologically certain forms, an hepatic injury is histologically constant. Aetiological, clinical, biological, diagnostic and therapeutic particularities connected with the hepatic localizations are considered and compared with findings of other authors. To remark, in Ivory Coast, on one hand the great predominance of Eberth bacillus aetiology, on the other hand the lack of statistically significative relation with drepanocytary waste. The pathogenic signification of the constancy of the hepatic injury and its peculiar histological pattern of non specific reactive hepatitis is discussed.
Sem Hop
PMID:[Hepatic manifestations in typhoid fever (author's transl)]. 624 6

After a clinical and pathological study of 55 cases of granulomatous hepatitis, the authors are trying to understand the data so that they can predict the etiology of the granulomas. The authors must insist on the necessity of homogeneity in clinical data, histological findings and ethnic origins.
Sem Hop
PMID:[Granulomas of the liver : a clinical and pathological study of fifty-five cases (author's transl)]. 625 34

One case of severe acute hepatic failure happening after surgical treatment of large tuberculous ureteral stenosis is reported. The etiology was the association of isoniazide-rifampicin; the clinical, biological and histological data of these hepatitis cases are specified; their physiopathology, as well as their treatment is studied; prevention by plasmatic evaluation of isoniazide is especially important.
Sem Hop
PMID:[Reversible acute hepatic failure after treatment with association of isoniazide-rifampicin (author's transl)]. 626 37

The authors describe a case of cure of chronic hepatitis B. This therapy chronic hepatitis B was corticotherapy dependent and the cure appeared during a treatment with basic aluminum hydroxide. This drug is an adjuvant of immunity. Clinical and biological disturbances disappeared. An improvement of the histological liver disturbances during hepatitis cure had been noticed. Three years later no recurrence was observed. After a short review of published literature, the authors discuss the mode of action of basic aluminum hydroxide.
Sem Hop
PMID:[Cure of chronic hepatitis B after treatment with basic aluminum hydroxide. One case report (author's transl)]. 626 8

A fatal case of active viral infection in a transplant patient is reported. On the second month post transplantation, Cytomegalovirus (CMV) infection occurred. It was attested by clinical and radiological symptoms, transient increase of transaminases and seroconversion with CMV antigen. Patient apparently recovered, but on the third month mucocutaneous Herpesvirus hominis (HVH) infection started. It was rapidly complicated by hepatitis and encephalitis which are directly responsible for the fatal outcome. A strain of HVH type 1 was easily isolated from oral and genital lesions. Immunofluorescence with HVH antiserum was positive on post mortem sample of liver biopsy Ultrastructural changes and intranuclear Herpesvirus like particles were demonstrated in liver. Etiology of hepatitis and management of immunosuppressive therapy are discussed.
Sem Hop
PMID:[Serial infections with two herpesviruses after renal transplantation: virological and ultrastructural features (author's transl)]. 627 Aug 6

Eight cases of hepatitis induced by amineptine chlorhydrate, a new tricyclic antidepressant are reported. Jaundice and/or biological changes occurred 16 to 75 days after the onset of treatment and with a total oral dose of 3,8 to 26 grams. Biologically, cholestasis and cytolysis have been observed simultaneously in 4 cases, cholestasis alone in 2 cases, and prevalent cytolysis in 2 others. After withdrawal of amineptine, clinical improvement was achieved within 10 to 21 days, whereas biological changes of hepatic function tests lasted for as long as 3 to 12 weeks. Physiopathology of such disorders is not clear : toxicity, enzyme induction, immunoallergy, may be considered as possible mechanisms.
Sem Hop
PMID:[Hepatitis, cholestasis and amineptine (author's transl)]. 627 80

Biologic hepatitis is common in secondary syphilis. Six cases are reported, in which stereotyped biologic changes were found. These consisted of very high alkaline phosphatase levels and gamma GT levels, with definite inflammation. Cytolysis was moderate or absent. Diagnosis can be established when these biologic anomalies are associated with strongly positive serologic tests for syphilis and rapid recovery under adequate treatment. In these cases, hepatic biopsy is unnecessary.
Sem Hop 1982 Jan 28
PMID:[Detection and incidence of hepatitis in secondary syphilis. Seventy case-reports (author's transl)]. 628 Feb 85

Seventy-five cases of acute poisoning with effervescent tablets of paracetamol have been recorded. No patients developed hepatitis. Ingested doses were low, and resulted only in minor manifestations. As each package contains only 6.6 g of paracetamol and effervescent tablets cannot be ingested in large quantities, the risk of serious overdosage is low.
Sem Hop 1982 Feb 18
PMID:[Acute paracetamol poisoning. A retrospective study of data from the Paris Antipoison Center. 1974-1981 (author's transl)]. 628 Mar 19


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