Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019158 (
hepatitis
)
30,205
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
This manuscript describes the case of a patient with sickle cell anemia who died of fulminant
hepatitis
after therapy with the iron chelator
Deferasirox
. The patient was homozygous for the -1774delG polymorphism in the
Abcc2
gene, which raises the concern about the use of hepatotoxic drugs in this specific context.
...
PMID:Deferasirox associated with liver failure and death in a sickle cell anemia patient homozygous for the -1774delG polymorphism in the
Abcc2
gene. 2878 27