Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019158 (hepatitis)
 30,205 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two virus strains which had been suspected to be the etiological agents of infectious bursitis (Gumboro disease) and of inclusion body hepatitis of chickens were characterized by their morphology, their peptide composition and the segmented genome of their double-stranded RNA to be typical reoviruses. Although the 2 avian strains did not clearly differ in their serological behaviour, the size of some of their RNA segments were not identical. Both strains replicated in tissue cultures prepared from the chorioallantoic membrane of embryonated eggs with growth characteristics of reoviruses.
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PMID:Structural and growth characteristics of two avian reoviruses. 17 Aug 88

A new peracute disease of chickens is described. The disease is called blue wing disease (BWD) and has occurred frequently in all parts of Sweden since the first outbreak in 1972. Most of the outbreaks have affected broilers at the age of 2 to 4 weeks with a mortality rate of 1 to 60%. BWD is characterised by skin lesions in the form of ecchymotic haemorrhages, most frequently on the wings. These lesions are often infected secondarily by bacteria, leading to a gangrenous dermatitis. Infectious bursal disease, inclusion body hepatitis and infectious aplastic anaemia, which also have been associated with gangrenous dermatitis, are not found in the outbreaks of BWD. BWD is closely related to certain parent flocks, which suggests that the disease is transmitted vertically. The parent flocks which transmit the disease do not show any signs of disease themselves.
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PMID:Blue wing disease of chickens: signs, pathology and natural transmission. 1876 15

In total, 39 clinical cases of fowl adenoviruses (FAdV) infection in chickens (28 broiler, 7 native, and 4 layer chickens) between 2007 and 2010 in Korea were investigated. The FAdV types 4, 8b, and 11 comprised 18, 9, and 12 clinical cases, respectively. All FAdV type 4 cases showed clinical hydropericardium (HPS) lesions as well as inclusion body hepatitis (IBH), whereas all FAdV types 8b and 11 cases exhibited IBH lesions without HPS. All 3 types were detected in broiler (9-30 d old) and layer chickens (23-112 d old), whereas most native chickens (14-65 d old) were affected only by FAdV type 4. Infectious bursal disease virus and chicken infectious anemia virus were complications in 51.3% of FAdV cases, with mortalities of 55% to <0.1%. Chicken infectious anemia virus was detected in all native chicken cases. These results indicate that preventive measures against FAdV infection and immunosuppressive diseases on poultry farms should be implemented.
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PMID:Epidemiological investigation of outbreaks of fowl adenovirus infection in commercial chickens in Korea. 2299 34