Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019158 (hepatitis)
30,205 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Abdominal pain is a common gastrointestinal symptom in children. The purpose of this paper is to determine the upper gastrointestinal mucosal pathology in a group of children with abdominal pain. 48 consecutive children referred to the authors with the problem of abdominal pain were studied. These were divided into 2 groups. Those with only one episode of pain and lasting for less than 2 weeks were considered to have acute abdominal pain. Those with repeated episodes of pain and lasting for more than 2 weeks were considered to have recurrent abdominal pain. Careful clinical examination was done to exclude an acute surgical abdomen. Other common causes of abdominal pain in our population such as urinary tract infection, lactose intolerance, hepatitis and choledochal cyst were excluded by clinical examinations and laboratory investigations. Upper gastrointestinal endoscopy was done by one of the authors. Five out of the 16 children with acute abdominal pain had macroscopic features of acute gastritis and another 2 had duodenitis. In the other 32 children with recurrent abdominal pain, 5 had duodenal ulcers and 3 had reflux oesophagitis. It was concluded that upper gastrointestinal endoscopy was a useful means of identifying the upper gastrointestinal pathology in children with abdominal pain. 43% and 25% of the children with acute and recurrent abdominal pain respectively had a cause identified by gastroscopy.
...
PMID:Upper gastrointestinal endoscopy in children with abdominal pain. 408 98

This research evaluated the anatomic pathology of rats fed diets containing ground beef which had been treated with aqueous chlorine. The anatomic pathology of 240 rats fed 92 d with diets containing ground beef treated with 0, 50, 200 or 600 ppm chlorine was carried out according to National Institutes of Health bioassay pathology procedures. The major rat tissues were evaluated and the incidence of histopathological conditions was recorded. The inclusion of chlorine-treated meat in the diet was not associated with any increase in incidence of neoplastic lesions, inflammatory lesions or degenerative changes. However, all male rats fed the meat diet both with or without chlorine exhibited mild to moderate hepatic fatty metamorphosis. In all likelihood, the fatty livers were due to the high fat content of the diet (about 35%). The adrenal glands of the control and treated males exhibited fatty metamorphosis. This effect is not explained by diet because even the male rats on the commercial rat feed had fatty adrenal glands. Other histopathologic conditions such as focal hepatitis, triaditis, focal myocarditis, focal lymphocytic infiltration, chronic murine pneumonia, chronic tracheitis, focal acute gastritis, dacryoadenitis, cataract, hyperplastic hepatic nodule or ultimobranchial cysts, when found were not associated with any treatment or sex group. The treatment of ground beef with aqueous chlorine before incorporation into a diet fed rats for 92 d exhibited no apparent effect on the anatomic pathology of rats.
...
PMID:Subacute Study of Rats Fed Ground Beef Treated with Aqueous Chlorine - Anatomic Pathology. 3096 86