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Query: UMLS:C0019158 (hepatitis)
 30,205 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

During the last ten years, several clinical manifestations of Yersinia enterocolitica infection have been reported. Surgeons are especially aware of "the right iliac fossa syndrome", caused by mesenterial lymphadenitis and terminal ileitis. We suggest that Yersinia enterocolitica may also cause a clinical condition easily misinterpreted as cholecystitis, and accompanied by slightly elevated serum levels of ASAT, LD, AP and bilirubin. Apparently, this condition may run a chronic relapsing course. A report is given of two cases of liver affection associated wtih positive Y. ent. antibody titre. Case 1 would illustrate the chronic relapsing liver affection with stationary titre. In Case 2 an acute Au-negative hepatitis is accompanied by significant rise and fall in titre.
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PMID:Liver affection associated with Yersinia enterocolitica infection. 61 Feb 87

Pseudotuberculosis caused by Yersinia enterocolitica was observed as an enzootic disease of the owl monkey (Aotus trivirgatus). A description is given of the natural disease and its successful reproduction in owl monkeys. The disease was characterized by purulent and necrotizing enteritis, hepatitis, and splenitis. Large colonies of the causative organism were consistently associated with the lesions. Although pseudotuberculosis has been reported in other monkeys, the disease in the authors' primate colonies has been restricted to the owl monkey.
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PMID:Pseudotuberculosis (Yersinia enterocolitica) in the owl monkey (Aotus trivirgatus). 82 25

The paper is concerned with a clinical description of yersiniosis in 12 women who suffered from manifest or uneventful cholelithiasis. The disease started by an attack of biliary colic. The clinical symptomatology was noticed to run in stages during which the signs of calculous cholecystitis vanished while the symptoms of hepatitis persisted. In the acute period, the conservative treatment of the patients was carried out by the infectionist jointly with the surgeon, followed by dispensary observation lasting 1 to 3 months until complete and stable normalization of aminotranferase activity. The outcomes were favourable.
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PMID:[The characteristics of the course of Yersinia hepatitis in cholelithiasis patients]. 181 59

Samples from 77 chital (Axis axis), 42 fallow (Dama dama), 26 red (Cervus elaphus), 7 rusa (Cervus timorensis) and 1 sambar deer (Cervus unicolor) were examined. Yersinia pseudotuberculosis infection was diagnosed as the cause of death in 6 (23%) of the red and 23 (30%) of the chital deer. Yersiniosis was the most common infectious cause of death diagnosed. Affected deer were usually found moribund or dead, often with faecal staining of the perineum. Gross pathology in chital included a fibrinous enterocolitis, enlarged congested mesenteric lymph nodes and multiple pale foci through the liver. Gross changes in red deer were limited to intense congestion of the intestinal mucosa and enlargement and congestion of mesenteric lymph nodes. Microscopic intestinal changes in both species consisted of microabscessation or diffuse suppurative inflammation of the intestinal mucosa with numerous bacterial colonies in the lamina propria. Multifocal suppurative mesenteric lymphadenitis was a common finding. Multifocal suppurative or non-suppurative hepatitis was frequently present in the liver of chital but was uncommon in the red deer. Yersiniosis occurred during the cooler months from June to November, with younger age classes most commonly affected. Y. pseudotuberculosis serotypes I, II and III were isolated in the ratio 17:3:0 in the chital deer and 1:1:2 in red deer. The clinical, epidemiological and bacteriological features are similar to those documented previously by New Zealand workers. The increased susceptibility to disease of red deer and chital compared to fallow deer and perhaps other species has not previously been documented.
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PMID:Yersiniosis in farmed deer. 222 64

Asymmetric affection of the major lower limb joints is a characteristic feature of the joint syndrome in yersiniosis-associated arthritis. The sacroiliac articulations are frequently (47% cases) involved. In addition, yersiniosis-associated arthritis concurs with the signs and symptoms of systemic disease--gastroenterocolitis, myocardiopathy and myocarditis, erythema nodosum, hepatitis, urethritis, conjunctivitis, myositis and myalgia, enteropathy; changes in the CNS typical for the astheno-neurotic syndrome are frequently present. Comparison of the immunological assay data in complicated and uncomplicated yersiniosis shows equally high levels of IgG and CIC. High anti-DNA antibody titres are more frequently found in the serum of uncomplicated yersiniosis patients. ELISA quantitation of specific IgA, IgM, and IgG class antibodies in yersiniosis-associated arthritis patients demonstrated persistence of all the three antibody classes or of IgA-IgG combination in cases with most severe of the joint syndrome. In the presence of cardiac disease, patients were found to have high titres of antibodies reactive with the cardiac interstitial tissue, while in authentically diagnosed myocarditis cases with the sarcolemma. The investigation findings strongly suggest a high degree of involvement of immune and autoimmune processes in the pathogenesis of arthritides secondary to Yersinia infection.
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PMID:[Clinico-immunologic characteristics of complicated and uncomplicated yersiniosis]. 277 63

Blood from endangered San Joaquin kit foxes (Vulpes macrotis mutica) inhabiting the Elk Hills Naval Petroleum Reserve, Kern County, and the Elkhorn Plain, San Luis Obispo County, California, was collected in 1981, 1982 and 1984 and sera were tested for antibodies against 10 selected pathogens. Proportions of kit fox sera containing antibodies against pathogens were: canine parvovirus, 100% in 1981-1982 and 67% in 1984; infectious canine hepatitis virus, 6% in 1981-1982 and 21% in 1984; canine distemper virus, none in 1981-1982 and 14% in 1984; Francisella tularensis, 8% in 1981-1982 and 31% in 1984; Brucella abortus, 8% in 1981-1982 and 3% in 1984; Brucella canis, 14% in 1981-1982 and none in 1984; Toxoplasma gondii, 6% in 1981-1982; Coccidioides immitis, 3% in 1981-1982; and Yersinia pestis and Leptospira interrogans serotypes canicola, grippotyphosa, hardjo, icterohaemorrhagiae, and pomona, none in 1981-1982. Although antibodies against selected pathogens were present, no clinical indications of disease were observed in these fox populations.
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PMID:Serological survey for selected diseases in the endangered San Joaquin kit fox (Vulpes macrotis mutica). 283 36

Circulating immune complexes are thought to play an essential part in the pathogenesis of necrosing angiitis. This theory also allows a role to be attributed to certain infectious agents (viral, bacterial, parasitic) in the development of periarteritis nodosa (PAN). An infectious syndrome was found in all our 9 patients, aged 26 to 69 years, with histologically confirmed PAN: previous infection (over 15 days before hospital admission): otitis, hepatitis B, tonsillitis, ascaris (Case n.7), pulmonary tuberculosis, brucellosis, seropositivity for Chlamydia trachomatis (Case n.9), paratyphoid (Case n.5), seropositivity for Yersiniosis pseudo-tuberculosis (Case n.2), seropositivity for Chlamydia trachomatis (Cases 3 and 4), seropositivity for toxoplasmosis (Cases 4 and 6), seropositivity for rubella (Case n.8). Recent infection (less than 15 days before hospital admission): staphylococcus aureus septicaemia (Case n.1); Group A betahemolytic streptococcal urinary infection (Case n.2); Group A betahemolytic streptococcal otitis media; pseudomonas aeruginosa and Klebsiella septicaemia; enterococcal cystitis (Case n.4); progressive pulmonary tuberculosis (Case n.6), acinetobacter pneumonia (Case n.9). The HBs antigen was only found in one patient (Case n.6), who had an active hepatitis.
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PMID:[The role of infection in the precipitation of periarteritis nodosa]. 290 81

A prospective study was undertaken to evaluate the incidence, course, effects of treatment and outcome of patients with Yersinia enterocolitica infections. A total of 189 patients were followed: 62.5% had enteric forms of illness, 20.6% extramesenteric forms, 23.2% arthritis and erythema nodosum. Lymphadenopathy with high fever and weight loss, a septic syndrome and hepatitis were predominant manifestations of the extramesenteric form. Ten per cent of the isolates (135) were susceptible to amoxycillin (4 mg/l), 38% to cephradine (8 mg/l), 82% to doxycycline (4 mg/l), 83% to chloramphenicol (4 mg/l), 85% to trimethoprim (1 mg/l), 87% to cefuroxime (8 mg/l), 92% to piperacillin (16 mg/l), 99% to gentamicin (1 mg/l) and 100% to cefotaxime (4 mg/l), pefloxacin (0.12 mg/l), ofloxacin (0.06 mg/l) and ciprofloxacin (0.016 mg/l). The majority of the patients with enteritis recovered without antibiotic therapy. The duration of enteritis was not significantly influenced by antibiotic treatment. Eighty five patients, 46 with enteric and 39 with extramesenteric forms were treated. The clinical response to co-trimoxazole was 71%, and to doxycycline 75%. Cefuroxime, ceftazidime, cefoperazone, piperacillin and gentamicin failed in seven of eight courses. Three patients treated with ciprofloxacin responded well. The role of quinolones in yersiniosis needs further attention.
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PMID:Antibiotics in Yersinia enterocolitica infections. 349 13

Liver involvement in infections with Yersinia enterocolitica or Yersinia pseudotuberculosis is apparently rare. In a 69-year-old male patient with acute Yersinia enterocolitica infection with positive faecal culture and a serum titre of 1/1280, the liver tests were slightly abnormal. A liver biopsy revealed granulomatous hepatitis. Follow-up after six months revealed normal liver function and histology.
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PMID:Granulomatous hepatitis in Yersinia enterocolitica infection. 359 57

Regarding of microbiological aspects of arthritis three forms of joint diseases are under investigation: the septic arthritis, the reactive arthritis and the Rheumatoid Arthritis. In 95% of patients with septic arthritis microorganisms as causative agents responsible for the disease are described: Staphylococci, Streptococci, some gram-negative bacteria. By an haematogenic route of infection predominantly patients with immunosuppressive therapy are altered. In newborns and children septic arthritis is to observe more rarely. A reactive arthritis is a postinfectious sterile process in dependence on an infection occurred at an earlier time. As etiologic agents Yersinia, Enterobacteriaceae and Campylobacter have been discovered. 80% of the patients suffering such a reactive arthritis are carrier of the HLA-B27 system. The etiology of the Rheumatoid Arthritis is an open, unanswered problem. Of importance are: immunogenetic conditions, autoimmune phenomena, endocrinologic, dietetic and psychologic factors as well as bacteria and viruses as causative agents: cocci, bacilli, Diphteroids, endoparasitic bacteria (Listeria, L-forms, Mycoplasma, Chlamydiae), viruses (Adeno-, Mumps-, Measles-, ECHO-, Coxsackie-A- and B-, Hepatitis-, Cytomegalo-, Para-influenza-, Retro-, Parvo- and Rubella viruses). In the last years the EBV is of interest covering the question of a distinct virus persistence in tissues and the adequate limiting factors. Perhaps a defect of the hu-IFN-gamma-system might be of immunopathological and clinical significance.
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PMID:[Microbiologic aspects of inflammatory joint diseases]. 367 41


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