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Query: UMLS:C0019158 (hepatitis)
 30,205 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Rocky mountain spotted fever is increasing in Florida, a state that has had few cases in the past. The typical clinical illness has been well described, but jaundice has been rarely reported. In two patients with illnesses resembling leptospirosis, jaundice appeared on the sixth and ninth day of illness, and peak bilirubin levels were between 7 and 9 mg/100 ml. Liver biopsy specimen from one patient showed a nonspecific hepatitis. Hemolysis and renal dysfunction may have contributed to the production of jaundice in these patients. Fourteen instances of jaundice were reported in 43 autopsied cases as of 1941, but since that time only rare mention of jaundice has been made.
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PMID:Rocky Mountain spotted fever and jaundice. Two consecutive cases acquired in Florida and a review of the literature on this complication. 62 53

We have reviewed 58 cases of bone marrow granuloma at a single institution over a 20-year time span, and have summarized the available English literature. We conclude that bone marrow granulomas are an infrequent pathologic finding which, when found, require definition as to an underlying etiology. Undoubtedly, the illnesses associated with marrow granuloma are similar to those causing granulomatous hepatitis. The following additional statements may justifiably be made based on this review. There are no morphologic features which allow reliable differentiation between the causes of bone marrow granuloma. By combining careful histologic, microbiologic, and serologic techniques, an etiology can be documented in most (87%) patients with marrow granulomas. A medication history is an important element of this evaluation. Rocky Mountain spotted fever, cytomegalovirus infection, ibuprofen, acute lymphocytic leukemia, and various collagen vascular diseases should be added to the list of causes of marrow granuloma. The prognostic significance of marrow granuloma in patients without an ascertainable underlying illness remains unclear.
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PMID:Granulomatous bone marrow disease. A review of the literature and clinicopathologic analysis of 58 cases. 631 87

The atypical measles syndrome is a relatively new disease that was first recognized 15 years ago. Initially, it occurred in children who were exposed to wild measles virus several years after they were immunized with killed measles vaccine. It was characterized by a two- to three-day prodrome of high fever, cough, headache, and myalgia followed by a rash that resembled Rocky Mountain spotted fever, scarlet fever, or varicella and associated with roentgenographic evidence of pneumonia with or without pleural effusion. This report highlights three unusual manifestations of this syndrome: 1) transient hepatitis, 2) persistence of pulmonary lesions for several years, and 3) occurrence of excessively high measles hemagglutination-inhibition antibody titers. Today, this syndrome occurs predominantly in adolescents and young adults.
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PMID:Atypical measles syndrome: unusual hepatic, pulmonary, and immunologic aspects. 746 41

Regarding problems in emergency and urgent immunoserologic tests, I mainly focused on infectious diseases and CPR and discussed the correspondence of dangerous needle stick injuries, and the significance of emergency CRP measurement in various body fluids using highly sensitive determination methods. The actual conditions and correspondence of infections due to dangerous needle stick injuries (accidental pricking with used needles) such as hepatitis, syphilis, acquired immunodeficiency syndrome (AIDS), adult T-cell leukemia (ATL), herpes simplex, falciparum malaria, tuberculosis, Rocky mountain spotted fever, and human colonic adenocarcinoma are discussed. With regard to emergency CRP measurement, application of highly sensitive determination methods and the significance of CRP measurement of various body fluids (healthy adult blood, cord blood, cerebrospinal fluid, urine and puncture fluid) are described. The reference values for CRP concentrations in various body fluids were established at 15 to 3,063 ng/ml for serum (male; 26 to 3.992 ng/ml, female; 11 to 1,672 ng/ml), 9 to 73 ng/ml for cord blood, 2 to 10 ng/ml for cerebrospinal fluid and less than 2 ng/ml for urine.
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PMID:[Future prospects of emergency laboratory tests--problems of immunoserologic tests]. 893 87

According to the Centers for Disease Control and Prevention (CDC), American health care workers suffer between 600,000 and 1 million needle sticks and other sharps injuries every year. Needle stick injuries are considered to be widely underreported. Eighty percent of blood contacts occur through needle sticks, making this the most common cause of health care work-related exposure to bloodborne pathogens. More than 20 pathogens can be transmitted through small amounts of blood. These include HIV, hepatitis B and C, other forms of hepatitis, syphilis, Rocky Mountain spotted fever, varicellazoster, and malaria. Hepatitis B is the most common infectious disease transmitted through work-related exposure to blood. The CDC reports that 5,100 health care workers become infected with hepatitis B each year through job-related blood contact. There have been 54 documented cases of HIV seroconversions among U.S. health care workers resulting from occupational exposures. Needle stick injuries caused by hollow-bore needles accounted for 86 percent of all reported occupational HIV exposures. Nurses make up 24 percent of the cases of HIV infection among health care workers known or thought to have been infected on the job. Research shows that 83 percent of these injuries can be prevented--most through the use of needles with safety features or needleless systems. According to the American Hospital Association, one case of serious infection by bloodborne pathogen can result in expenditures of $1 million or more for testing, follow-up, time lost from work, and disability payments. The cost of follow-up for a high-risk exposure is almost $3,000 per needle stick injury, even when no infection occurs. Safe needle devices cost about 28 cents more than standard devices.
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PMID:Needle stick injuries: nurses at risk. 1204 May 56