Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019158 (hepatitis)
 30,205 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An adenovirus, designated T-75 isolant, was isolated from the cloacal swab of a clinically normal turkey, 13 weeks old. The T-75 isolant was identified as an adenovirus on the basis of physicochemical properties, cytopathology, and agar-gel precipitin test. Producing two-way cross-neutralization reactions with CELO virus, the isolant was classified as an avian adenovirus of serotype 1. The T-75 isolant was pathogenic to both chicks and turkey poults, causing hepatitis, respiratory disease, atrophy of the bursa of Fabricius, and/or growth depression of experimentally inoculated birds, varying with the host and route of inoculation.
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PMID:An adenovirus from a turkey pathogenic to both chicks and turkey poults. 18 10

This paper gives, in detail, the causes of either liver disease or hepatomegaly in 100 patients, mostly adults, admitted to the medical wards of Angau Memorial Hospital, Lae, during 1968 and 1969. The major findings included liver cell carcinoma, cirrhosis (often with chronic active hepatitis), tropical splenomegaly, pericholangitis and hepatitis. There were 27 with miscellaneous findings including ten with normal, or almost normal, livers despite the definite enlargement. Patients with liver cell carcinoma presented late in the course of their illness and had a poor prognosis. Others, with pericholangitis, had clinical features of portal hypertension indistinguishable from that complicated cirrhosis. There was an unexpected number with chronic active hepatitis and a liver biopsy is essential for such a diagnosis. Hepatic sinusoidal lymphocytosis is almost invariably found in patients with TS but may occasionally be found in those with a non-palpable spleen. Patients with right heart failure of chronic respiratory disease, and jaundice of acute pneumonia were excluded from the study.
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PMID:Liver disease in Papua New Guinea. 19 19

This report presents information on the range of diseases and lesions that occurred in sections of livers of macropods held in the Non-Domestic Animal Registry at Taronga Zoo. Of 142 affected livers, 52 were due to parasites, 24 to bacteria, nine to Macropod Herpesvirus, four to fungal agents and ten to tumours. In addition, 17 livers had acute degenerative or necrotic lesions, 22 were affected by fibrosis or other chronic lesions and four had miscellaneous degenerative lesions. Common parasitic diseases included toxoplasmosis, coccidial cholangitis, cestode cholangitis (Progamotaenia sp.), fascioliasis and capillarial hepatitis. Bacterial diseases were varied but lesions due to anaerobic bacteria or Mycobacteria spp. were most common. Many of the acute degenerative lesions were associated with cardio-respiratory disease. Chronic lesions were often of unknown origin, although it was speculated that parasitic and bacterial organisms contributed to the aetiology. There were four primary and six metastatic tumours.
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PMID:A survey and review of hepatobiliary lesions in Australian macropods. 145 9

To assess how the occupational medicine literature may affect general medical practice, representative journals were reviewed to address (1) how frequently the specialties cite each others' literature and (2) which topics are published most commonly by the respective journals. Five general medical journals were selected to contrast with six occupational medical journals. Methods included Journal Citation Reports, which enable the tabulation of impact factor, self-citation rate, and the number of source items published by the journal. MEDLINE was used to cross reference the 11 journals with designated topics in occupational medicine. The findings indicated that occupational medical journals are nearly 50 times more likely to cite the general medical literature than the converse. The journals most likely to cite the core occupational medical literature, aside from the specialty journals themselves, were the American Review of Respiratory Diseases and the American Journal of Epidemiology. In comparing the 1976 through 1980 period with the 1986 through 1990 period, occupational medical journals published 2.5 times as many source items (letters, technical reports, and papers) compared with a decade earlier. The MEDLINE search indicated that both types of journals address the same types of occupational medicine topics with the exception of gas poisoning and toxic hepatitis, which were published much more frequently in general medical journals. Pneumoconiosis was the most frequently addressed topic by occupational medical journals. Other major categories included reproductive hazards, lead poisoning, and noise-induced hearing loss. This study indicates that occupational medicine, as reflected by its journals, is a much more active scientific discipline than it was a decade earlier.
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PMID:The influence of occupational medicine on general medicine: a look at the journals. 154 80

The incidence and morbidity of viral and Toxoplasma gondii infections were studied in 40 children who underwent liver transplantation between December 1983 and February 1988. The incidence of primary and reactivated cytomegalovirus (CMV) infection was 19% and 47%, respectively; primary infection caused clinical disease in all five cases affected and was fatal in one. Primary Epstein-Barr virus (EBV) infection occurred in 10 (26%) recipients but caused only mild disease. No reactivated EBV infection was recorded and no lymphoproliferative disorders associated with EBV were found after a maximum of four years' follow up. Adenovirus infection occurred in seven (18%) patients; this was associated in one case with fatal pneumonia and fulminant hepatitis, but otherwise with only mild respiratory disease. Primary T gondii infection was detected in one patient who remained asymptomatic. Other viruses causing infection included herpes simplex, varicella zoster, and respiratory syncytial virus. Surveillance for these infections and the long term sequelae should be included in the follow up of all children who undergo transplantation.
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PMID:Viral and toxoplasma gondii infections in children after liver transplantation. 215 47

The lesions and etiologic agents associated with 13 outbreaks of respiratory disease in commercial chickens were investigated. Adenoviruses were isolated from tracheal and lung tissues of affected chickens in all 13 outbreaks. Escherichia coli was isolated from the lung of an occasional bird. The tracheal specimens were consistently negative for Bordetella avium, but E. coli and occasionally Staphylococcus aureus were isolated. There was also serological evidence in one outbreak, and pathological evidence in another, of a concurrent infectious bursal disease virus (IBDV) infection of chickens affected with the disease. Gross and microscopic alterations in the tracheas and lungs of affected chickens were similar in all outbreaks and consisted of catarrhal tracheitis and occasionally multifocal pneumonia with mononuclear cell infiltrates. Hepatitis and splenitis with heterophil infiltrates occasionally were seen in birds with coliform septicemia. The tracheal and lung lesions in the present investigation were considered primarily of adenovirus etiology, complicated by secondary bacterial infection.
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PMID:Adenovirus infection associated with respiratory disease in commercial chickens. 282 79

Sixteen avian adenoviruses isolated from 12 cases of inclusion body hepatitis (IBH), 3 cases of respiratory disease, and a case of ruptured tendons were compared using antisera raised against 9 fowl adenovirus prototype strains. Eleven isolates from livers of birds with IBH were classified into 4 different serological groups: 1) YR36 (type 7)-related; 2) HVI (type 8)-related; 3) Variants--type 6-,7-, and S-related; and 4) Type 50--not closely related to any of the prototype antisera tested. These results indicate that, as in other countries, IBH in Victoria is associated with several serologically distinct adenoviruses. The other five adenovirus isolates were found to be related to CELO (type 1).
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PMID:Serological identification of avian adenoviruses isolated from cases of inclusion body hepatitis in Victoria, Australia. 626 46

The incidence and characteristics of P1-antibodies in Scottish pigeon fanciers has been assessed. Of 223 individuals participating in the study, 23.3% were P1-negative and of these, 53.9% had detectable P1-antibodies. These antibodies were shown to belong to the IgM class and the highest serum levels were found in those pigeon fanciers with symptoms of respiratory disease who were sensitized to pigeon antigens. Of pigeon fanciers' sera, 10.3% gave false positive reactions for the Hepatitis B surface antigen in a reversed passive haemagglutination test. The reactions were most prevalent in sensitized fanciers and were shown to be directed not against the absorbed HBsAg antibody, but against the turkey red cells used as carriers in the test. No relationship was observed between the existence of P1-antibodies and false-positive hepatitis reactions. It was concluded that the inhalation of avian antigens by pigeon fanciers can induce the production of at least three distinct populations of antibodies. No evidence was obtained to imply any special role for P1-antibodies in the aetiology of pigeon fanciers' disease.
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PMID:A survey of P1-antibodies in Scottish pigeon fanciers. 746 Feb 59

A retrospective study was undertaken in Crete, Greece, to investigate the epidemiologic, clinical, and therapeutic aspects of Q fever. Over a period of 5 years (1989-1993), 1,298 patients were examined and 98 cases were identified. Individuals who were aged 20-29 years and 30-39 years appeared to have an increased risk of infection. Contact with animals was found to be a major risk factor for acquisition of Q fever. The predominant clinical manifestations of the infection were fever (91.7% of patients) and respiratory disease (88.5%), whereas hepatitis was the dominant feature in only a minority (7.1%) of patients. Chest radiographs frequently revealed pulmonary interstitial changes (36.4% of patients) and alveolar changes (34.4%). Abnormal echocardiographic findings were also observed. There was no difference in the duration of fever whether the patient received therapy with tetracycline or erythromycin, a finding that may be explained by the delay in initiating tetracycline therapy.
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PMID:Q fever in the Greek Island of Crete: epidemiologic, clinical, and therapeutic data from 98 cases. 762 16

Infections by alpha-herpesviruses of dogs (canid herpesvirus, CHV) and cats (felid herpesvirus, FHV) are widespread in these species and are of significant clinical relevance. Immunologically closely related herpesviruses have been isolated from harbour seals (Phoca vitulina) showing respiratory disease, hepatitis and/or encephalitis. These isolates are currently referred to as phocid herpesviruses (PhHV). The host spectrum of CHV and FHV, respectively, appears to be restricted to members of the Canidae and Felidae families. Seal herpesviruses, in contrast, cross species barriers, at least in vitro where they productively replicate also in cells of felid origin. Whether cats are susceptible to natural PhHV-infections remains to be elucidated. A reliable etiological diagnosis of acute herpesvirus-associated infections should be desirable especially in breeding kennels and zoos where hosts susceptible for FHV, CHV oder PhHV are reared. For a rapid and unambiguous identification and differentiation of herpesvirus isolates derived from felids, canids and pinnipedia a simple enzyme immunoassay employing monoclonal antibodies is presented.
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PMID:[Simplified identification and differentiation of feline, canine and phocine herpesvirus isolates using monoclonal antibodies]. 785 45


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