Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019158 (hepatitis)
 30,205 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Sporadic non A, non B hepatitis non related to blood transfusions or parenteral exposure is present in India and various countries of southeast Asia and Africa. We present the experience in a northeastern region of Argentina from January 1987 to September 1990. During this period twenty one patients where identified with acute hepatitis without serologic evidence of infection with HAV, HBV, HCV, toxoplasmosis, infectious mononucleosis nor clinical evidence of Herpes virus infection. Clinic and biochemical parameters were analyzed and showed a considerable elevation of transaminases and cholestasis. Of the 21 patients diagnosed as having acute non A non B hepatitis of probable enteric transmission (NANBE), 10 where male and 11 female. Mean age was 24.7 years. In all cases the disease was self limited and follow up during more than one year after the acute episode did not demonstrate signs of reactivation nor evidence of chronicity.
 ...
PMID:[Sporadic non-A, non-B hepatitis in Argentina. The responsibility of the hepatitis E virus?]. 134 Aug 27

Herpesvirus infection was diagnosed in a toucan. The herpesvirus was isolated from the liver and identified by electron microscopy in the liver and in cell culture. A negative immunofluorescent reaction was obtained when virus-infected cell cultures were reacted with a conjugate to the herpesvirus of Pacheco's disease. The main pathologic finding in the toucan consisted of a severe necrotizing hepatitis with intranuclear inclusions in the liver and spleen. A presumptive diagnosis of chlamydiosis was also made, based on a positive direct fluorescent monoclonal antibody reaction to chlamydial antigens in impression smears of liver and spleen. Chlamydial isolation attempts were unsuccessful. The toucan had been in contact with two macaws that had died 5 days before the toucan died and were diagnosed by histology as having herpesvirus hepatitis.
 ...
PMID:Herpes viral hepatitis in a toucan. 217 40

Herpesvirus infection in tortoises is largely characterized by the development of respiratory clinical signs. Usually lesions develop in the respiratory, oral pharyngeal, intestinal tract and are accompanied by cutaneous and ocular lesions. In chelonids affected by herpesvirus, systemic-type lesions in organs such as the liver and spleen are commonly observed. In this paper we describe a case of multifocal necrotic hepatitis associated with herpesviruses in an adult female land tortoise of the species Testudo horsfieldii. This article is the first description of a viral hepatitis in Testudo spp. with lesions compatible with herpesvirus infection, with no clinical signs or lesions in the respiratory system, oral cavity or other organs.
 ...
PMID:Hepatitis associated with herpes viral infection in the tortoise (Testudo horsfieldii). 1200 20

Herpesvirus infection was diagnosed in two parrots that died suddenly in a pet shop. Gross lesions were confined to reddening of the small intestinal mucosa. Histological examination of tissues from one specimen revealed a hepatitis and splenitis accompanied by intranuclear inclusions. Cowdry type A inclusions were observed in tissue culture and within the nuclei of chick embryo hepatocytes. Virus particles with a morphological similarity to herpesviruses were identified in electron microscope studies. The condition was considered to represent a case of Pacheco's parrot disease.
 ...
PMID:Herpesvirus infection resembling Pacheco's disease in Amazon parrots. 1877 Apr 48