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Query: UMLS:C0019158 (hepatitis)
 30,205 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

With the aim to evaluate the influence of gastric resection on the morphological and functional conditions of the liver and the eventual appearance of gallstones, 50 randomized patients with a resection of the stomach were clinically analysed at different period of time, together with 50 patients suffering from peptic ulcer. All patients underwent a liver biopsy, 26% of the patients with gastric resection and 20% of the patients with peptic ulcer showed pathological findings of the liver, which statistically is not a significant difference. The most frequent pathologic change in both groups was a persistent hepatitis, while gallstones rarely occurred. Further, a presence in the past of viral hepatitis and alcoholism in both groups has been analysed as possible factors for the mentioned changes in the liver. Hbs Antigen detection has also been drawn as important. People with gastric resection belong to the jeopardized groups of the population with a great risk-factor related to previous frequent blood transfusion and other medical procedures. Patients who underwent a gastric resection, were analysed for the influence of the time period, following operation, on proved lesions of the liver, which were also observed in relation to dumping syndrome, malnutrition and other postresection syndromes. The authors point out the importance of making an early detection of the lesions of the liver, during surgery, with the aim to prevent the development of severe chronic inflammation.
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PMID:[Gastric resection and the hepatobiliary tract]. 688 May 42

Frank intrabiliary rupture of hepatic hydatid cysts is not uncommon in Iraq. Thirteen patients have been studied and three types of presentations described: i) typical, a patient with known hydatid cyst of the liver presents with pain, fever and jaundice; ii) asymptomatic, in a patient with hepatic hydatid cyst; and iii) atypical, simulating cholelithiasis, liver abscess, peritonitis, hepatitis and persistent biliary fistula.
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PMID:Intrabiliary rupture of hepatic hydatid cyst. 718 12

Nonalcoholic steatohepatitis is a poorly understood and hitherto unnamed liver disease that histologically mimics alcoholic hepatitis and that also may progress to cirrhosis. Described here are findings in 20 patients with nonalcoholic steatohepatitis of unknown cause. The biopsy specimens were characterized by the presence of striking fatty changes with evidence of lobular hepatitis, focal necroses with mixed inflammatory infiltrates, and, in most instances, Mallory bodies; Evidence of fibrosis was found in most specimens, and cirrhosis was diagnosed in biopsy tissue from three patients. The disease was more common in women. Most patients were moderately obese, and many had obesity-associated diseases, such as diabetes mellitus and cholelithiasis. Presence of hepatomegaly and mild abnormalities of liver function were common clinical findings. Currently, we know of no effective therapy.
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PMID:Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. 2901 67

Expert judgement of selected gastro-intestinal disorders, as well as of pancreatic and liver disease and of the status after gastric surgery is discussed. The group of liver disease commented upon includes virus hepatitis as a disease caused by professional activity, fatty liver, chronic hepatitis and cirrhosis of the liver. A causal relationship between progressive liver disease and peptic ulcer has to be accepted; a causal relationship between most types of liver disease and cholelithiasis however has not yet been established. In conclusion, the advantages are stressed of an early mobilisation of patients with chronic liver disease as well as the positive effects of physical therapy upon the course of the disease, the psychological and general status of the patient.
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PMID:[Expert judgement of gastro-intestinal disease in Austrian social medicine (author's transl)]. 743 75

Several antibiotics can cause severe hepatic injury. It is the purpose of this paper to review the main antibiotics that can cause hepatic injury and discuss the presentation, pattern, and outcome of hepatic injury. In the case of the penicillins, the combination amoxycillin-clavulanate and the penicillinase-resistant penicillins oxacillin, (di-)cloxacillin, and flucloxacillin can cause (mainly cholestatic) hepatitis. Cephalosporins have little hepatotoxicity; ceftriaxone can cause drug-induced gallstones. The potential of erythromycin and several other macrolides to cause (usually cholestatic) hepatitis is well established. Tetracyclines can cause a syndrome mimicking acute fatty liver of pregnancy, but this complication has virtually disappeared. Quinolones seem to be able to cause cholestasis. Sulfamethoxazole/trimethoprim can cause severe hepatotoxicity, especially in patients with acquired immunodeficiency syndrome (AIDS). Finally, nitrofurantoin can cause acute cholestatic and hepatocellular reactions as well as chronic hepatitis mimicking chronic auto-immune hepatitis.
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PMID:Hepatotoxicity of antibiotics. 749 42

The purpose of this clinical study was to demonstrate the usefulness of routine intraoperative cholangiography (IOC) and the safety of laparoscopic cholecystectomies (LC) in a community hospital. There were no ductal injuries and perioperative complications were extremely low. Patients (n = 236) with symptomatic gallstone disease, acalculus cholecystitis, or gallbladder polyps underwent LC from March 1991 to June 1993. During this period two patients were not considered appropriate candidates for this procedure. There were 172 women and 64 men ranging in age from 15 to 84 years. Four had preoperative endoscopic retrograde cholangiopancreatographies (ERCPs) for suspected choledocholithiasis. Elective LC was performed on 194 patients and emergency LC on 42 patients. The average operating time for elective LCs was 89 min and 97 min for emergency LCs. Thirty-six percent of patients had previous abdominal or pelvic surgery. IOC was attempted in 99% of patients and successful in 89%. Five percent had choledocholithiasis. Laparoscopic duct exploration was performed on four patients. Six patients had postoperative ERCP with stone extraction. Three percent of elective patients had additional surgery. One patient had LC during pregnancy (17 weeks), with a normal recovery and successful outcome of the pregnancy. Six elective and four emergency patients were converted to open cholecystectomy, a conversion rate of 4%. There were no ductal or vascular injuries, intraoperative haemorrhages or deaths. There were one small bowel laceration (0.4%). Postoperative complications included seven wound infections (3%), four bile leaks (2%), three trocar site haemorrhages (1%), one intraabdominal haemorrhage (0.4%), one suspected halothane hepatitis (0.4%), one drug-induced cholestatic jaundice (0.4%), and one subcutaneous emphysema (0.4%).(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Laparoscopic cholecystectomy: a continuing plea for routine cholangiography. 773 40

Within the "primary" cholestasis we can discriminate "essential" forms due to an endogenous biochemical error of bile acid metabolism and/or secretion and "conditioned" forms, in which a known precipitating factor is required to elicit the functional disorder responsible for cholestasis. Among the essential forms of cholestasis must be included benign recurrent intrahepatic cholestasis or Summerskill-Walshe disease, Aagenaes disease, progressive familial intrahepatic cholestasis or Byler's disease, and forms due to disorders of the peroxisomes. Benign recurrent intrahepatic cholestasis, the best known form, is characterized by recurrent episodes of itching and jaundice with an acute onset separated by symptom-free intervals, which shows no tendency to progress to liver failure. The conditioned cholestasis group comprises cholestasis of pregnancy and drug-induced cholestasis. Benign recurrent cholestasis of pregnancy is a form induced "by" pregnancy and not a form occurring "in" pregnancy, such as cholestasis due to hepatitis, to primary biliary cirrhosis, to cholelithiasis. Drug-induced cholestasis is a chapter of great clinical relevance: forms due to steroid hormones and due to phenothiazines are discussed.
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PMID:[Intrahepatic cholestasis due to biochemical errors of bile acids. II. Clinical and therapeutic aspects]. 785 57

One hundred and sixty-five patients with cirrhosis were prospectively investigated, by regular ultrasonographic follow up, to assess the incidence of gallstones. The mean length of follow up was 33 months (range 12 to 108). Cholelithiasis was diagnosed in 31 patients (18.8%), with a cumulative incidence over 84 months of 38.3% (4.7% yearly incidence). The risk of gallstones was similar in males (38%) and females (38.3%), although the final cumulative incidence was reached at 72 months in males. The percentage of patients with new stones was higher in alcoholic cirrhosis (28.9%) (with a cumulative incidence of 48.8% at 84 months) and lower in hepatitis-related cirrhosis (1.9%) (only one new case at 96 months of follow up) (p < 0.001). The cumulative incidence of gallstones in the Child's C group reached 49.3% at 48 months versus 24% in Child's B and 6.4% in Child's A (p < 0.0001). At multivariate analysis, Child's C and alcoholic cirrhosis were shown to be the independent variables significantly associated with a high risk of development of cholelithiasis. This study confirms that cirrhosis represents a high risk factor for gallstones. The risk is greater for alcoholic cirrhosis and increases with the severity of the disease.
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PMID:Incidence of gallstones in a population of patients with cirrhosis. 793 Apr 81

Experience in surgical treatment of 53 patients with internal biliodigestive fistulas is analysed. The formation of the fistula in all cases was caused by cholelithiasis with obstruction of the bile ducts, purulent cholangitis, angiocholitis, cholangiolytic abscesses of the liver, pancreatitis, hepatitis, as well as cholelithic ileus. Cholecystectomy, removal of the stones from the bile ducts, restoration of the main route of bile drainage, elimination of the pathological communication, and closure of the defect in a hollow organ should be considered the operation of choice. In cholelithic ileus operation for correction of the intestinal obstruction is also expedient. Postoperative complications were encountered in 35.8% of cases. Hepatorenal insufficiency developed in 8, incompetence of the choledochus sutures in 3, an external biliary fistula in 2, hepatic abscess in 1, pancreatitis in 2, and suppuration of the postoperative wound in 3 patients. Among the 53 patients treated by operation, 49 (92.5%) recovered and 4 (7.5%) died from various postoperative complications.
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PMID:[Internal biliodigestive fistulas]. 829 90

This article is based on the review of more than eighty references involving clinical treatment, analgesia, auriculoacupoint for diagnosis and its mechanism. In the first part, selection of acupoints, methods of manipulation, therapeutic effects and related experience in 56 kinds of respiratory, circulatory, digestive, urological, gynaecological, obstetrical, pediatric, otolaryngologic and ophthalmologic, dermatologic diseases and diseases of the nervous systems, as well as treatment of acute abdominal diseases, reduction of body weight, abstinence from smoking and drinking, etc. are discussed. A variety of stimulation methods, such as auriculoacupuncture with filform needles, needle embedding therapy, point injection, bloodletting, laser irradiation, aurioular plaster and pressing therapy, etc are also introduced. In the second part, experiences of surgical operation and endoscopy under auriculoacupuncture anesthesia are described. The third part deals with diagnosis using auriculoacupoints. Also described in this part is the clinical application of auricular acupoints in the diagnosis of cancers, coronary diseases, cholelithiasis, hepatitis, tertian malaria, etc. The correlation between the morphology and function of auricular acupoints, i.e. the relationship between auricular acupoints and visceral function, and main development in clinical therapy, diagnosis and mechanism of auriculoacupuncture are introduced in the fourth part, including the results of investigations of reactions of auriculoacupoints during disorders of the body and viscerae, reactions of viscerae during stimulation of auriculoacupoints and their transmission routes. Based on the analysis of the history and current status of research on auriculoacupuncture, the author emphasizes the necessity of attaching importance at the same time to prophylaxis and treatment of serious diseases and standardization of nomenclature. Suggestions in this connexion are also made.
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PMID:Recent studies on auriculoacupuncture and its mechanism. 841 88


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