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Query: UMLS:C0019087 (hemorrhagic diathesis)
 678 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Here are the most important pathomorphological findings recorded from 14 calves or heads of young cattle following whole-body X-ray treatment (170 R and u50 R median-line dosage): 1. Damage was caused to the haematopoietic system, with the most severe effects on granulopoiesis, thrombocytopoiesis, and lymphopoiesis, but less conspicuous lesion of erythropoiesis. 2. Haemorrhagic diathesis developed together with pneumonia in 86 per cent of all cases, manifested in most of them as severe fibrinous pneumonia and pleuropneumonia (in 75 per cent of the cases) and progressing pericarditis. 3. Liver degeneration occurred to all animals, usually in the form of centrobular liver cell necrobiosis (86 per cent), with most of the cases accompanied by diffuse degenerative hepatoparenchymal damage (80 per cent) as well as by granular degeneration of the myocardium and acute fubulonephrosis, the latter two processes obviously developing only short time before death. 4. Catarrhal as well as fibrinous and circumscribed diphtheroid enteritis developed in 43 per cent of all animals, those which had received a median-line dosage of 170 R. 5. Deficiency in supply was recorded, too, with severe damage to the haematopoietic organs being in the focus of the pathological process. That damage actually was the cause of the haematologically established granulocytopenia or agranulocytosis, thrombocytopenia, and lymphopenia. That was the background against which radiation syndrome of calf could be accompanied by activation of latent or subclinical infection of respiratory organs and the development of severe pneumonia as well as by changes in the intestinal flora leading to the outbreak of enteritis. The collapse of cellular defence mechanisms obviously caused intestinal induction of resorption of bacterial toxins and decomposed tissue products, with the pneumonia-damaged lungs being involved. The results eventually were intoxication with haemodynamic disorders, increase in vascular permeability, and degenerative damage to the parenchyma. Haemorrhagic diathesis was the result of thrombocytopenia and, possibly, endotoxic or toxic damage to the coagulation and blood vessel system. Further pathogenetic aspects relating to the radiation syndrome in calf and young cattle are discussed.
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PMID:[Pathomorphology and pathogenesis of radiation sickness in calves and young cattle following whole body roentgen irradiation]. 72 76

This paper discusses causes, hemodynamics, symptoms, and signs of pulmonary embolism. Severe cases obstruct at least 60 percent of the pulmonary vascular bed. Small or moderate cases may be easily overlooked. Symptoms may be only slight chest pain or dyspnoea, fever, giddiness, or irregular heart beat. In the author's experience with 35 cases of acute massive pulmonary embolism at the Bromptom Hospital oral contraceptives were considered a predisposing factor in 5 cases (14 percent), pregnancy was a possible cause in 2 (6 percent), a recent operation in 24 (68 percent). No other recognized factor was thought to have predisposed more than a single case. Clinical features included cyanosis, collapse, sever chest pain, dyspnoea, sweating, rapid heart rate, falling blood pressure, and occasional coughing up of blood. Electrocardiograms sometimes gave helpful information. Chest x-ray was usually not helpful except to exclude other causes. Heart catheterization and pulmonary arteriography have been done to assess the extent of the embolism. Emergency surgical pulmonary embolectomy is recommended for extreme cases. Fibrinolytic agents such as streptokinase may be adequate for less severe cases who have not had a recent operation of do not suffer from a hemorrhagic disorder.
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PMID:Pulmonary embolism. 535 32

Leptospirosis is a worldwide zoonosis affecting wild and domestic mammals. It is most commonly transmitted to humans by indirect contact with infected animals. Vascular injury, mainly capillary damage, and hemorrhagic diathesis are prominent features in the affected organs. The most severe form of the disease presents with high fever, intense jaundice, hemorrhagic diathesis, hepatic and renal dysfunction, mental status changes, and cardiovascular collapse. Focal or diffuse areas containing alveoli filled with erythrocytes characterize the pulmonary involvement. These latter conditions, although unusual, are associated with significant mortality.
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PMID:Pulmonary leptospirosis. 1095 36

In our cohort of 555 patients with a total of 1150 vertebral fractures treated with kyphoplasty we performed a 30-day postoperative analysis of cement leakage, neurological symptoms, pulmonary embolism, and infections. In our department, 22% of kyphoplasties were performed with calcium phosphate cement and the remainder with polymethylmethacrylate. All patients were initially assessed by an interdisciplinary kyphoplasty colloquium, composed of consultants in traumatology, radiology, and endocrinology. Indications included fresh traumatic vertebral fractures; painful sintered osteoporotic vertebrae; osteolysis and painful vertebral body collapse caused by multiple myelomas; and lymphomas and pathological fractures due to metastases of malignant tumors (prostate cancer, breast cancer, ovarian cancer, and malignant melanoma) or benign vertebral tumors (hemangioma). Contraindications included patients with instability of the posterior wall and/or pedicles, an infection of the fractured vertebra, a severe hemorrhagic diathesis, known allergies to the cements, pregnancy, and ASA score of 4. The standard postoperative computed tomography scan of the kyphoplasty-treated vertebrae revealed a dorsal cement leakage in 38 vertebrae representing 3.3% of all levels. A permanent monoparesis of the left leg, 2 cases of temporary neurological deficits, 2 cases of hemorrhage, and 1 asymptomatic pulmonary embolism were observed as postoperative complications. We observed no complications relating to polymethylmethacrylate described in the literature. By careful interdisciplinary indication setting and a standardized treatment model, kyphoplasty presents a safe and effective procedure for the treatment of various vertebral fractures.
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PMID:1150 kyphoplasties over 7 years: indications, techniques, and intraoperative complications. 1930 1