Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0019079 (
hemoptysis
)
6,129
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We studied 18 patients, 9 women and 9 men, ranging in age from 18 to 76 years. The main symptom was
hemoptysis
and the underlying pathology was tuberculosis, actinomycosis, lung cancer, metastatic carcinoma and systemic lupus. Nonsurgical patients, with recurrent
hemoptysis
or massive bleeding were selected. The embolization substances were spongostan, avitene (R) and
PVA
; they all produce temporary as well as persistent hemostasis. The procedure was successful in 16 patients. In two patients the embolization was not performed, one for technical reasons and the other because the vessel to be treated was the source of an anterior spinal artery. It is considered that the endovascular treatment constitutes an alternative for
hemoptysis
, even during the acute period, mainly in the management of nonsurgical patients.
...
PMID:[The endovascular treatment of hemoptysis]. 134 Sep 2
Bronchial arteriography and embolotherapy were performed to control
hemoptysis
in 11 patients with advanced stages of cystic fibrosis. Two patients suffered massive, 1 moderate, and 8 mild but recurrent
hemoptysis
. The embolization procedures were performed with Gelfoam,
Ivalon
, and coils in one to four separate procedures. Altogether, 19 of 20 procedures were successful, with follow-up periods ranging from 9 months to 8 years. No serious complications were encountered except for one femoral artery pseudoaneurysm which required surgical repair. Rapid digital subtraction angiography and "roadmapping" were considered helpful in avoiding the complication of reflux embolization and expediting the procedures. Bronchial embolization is a life-saving procedure for severe
hemoptysis
in patients with cystic fibrosis and is considered safe enough to include the indications of moderate and mild/recurrent
hemoptysis
to improve the quality of life in these patients.
...
PMID:Bronchial arteriography and embolotherapy for hemoptysis in patients with cystic fibrosis. 191 38
Forty-four patients with massive or repeated
hemoptysis
due to nonneoplastic lung diseases were treated by embolization of the bronchial and non-bronchial systemic arteries with
Ivalon
particles or a mixture of
Ivalon
and gelatin sponge particles during the past five and a half years. Immediate control of
hemoptysis
was achieved in 43 patients (98%), and no spinal cord ischemia was observed. Among 30 patients followed for more than 12 months, successful control of
hemoptysis
was obtained in 22 (73%).
Hemoptysis
recurred in eight patients (27%); four underwent repeated embolotherapy alone, two underwent surgery alone, and two underwent repeated embolization and surgery. Successful control of
hemoptysis
was achieved after repeated embolization and/or surgery in all eight patients. It is concluded that embolization of bronchial and non-bronchial systemic arteries is an effective initial treatment for
hemoptysis
, and good long-term results can be obtained in combination with surgery.
...
PMID:[Bronchial and non-bronchial systemic artery embolization for hemoptysis due to non-neoplastic lung diseases. Immediate effect and long-term results]. 194 83
Massive
hemoptysis
and/or recurrent expectoration of measurable amounts of blood are common complications of chronic bronchopulmonary infections in cystic fibrosis (CF). When conservative treatment fails to control bleeding, surgery or bronchial artery embolization (BAE) is frequently considered. We present our experience and long-term follow up of BAE in 14 CF patients (age range 15-39 years) with massive (6 subjects) and/or recurrent (8 subjects)
hemoptysis
not responsive to medical treatment. Seven had chronic hypercapnic respiratory failure. After angiographic evaluation, polyvinyl alcohol particles (
Ivalon
) were injected to embolize obviously enlarged bronchial arteries. Seventeen procedures were performed in 14 patients and 36 bronchial arteries were embolized. All the patients stopped bleeding immediately upon BAE. Most of the patients had postembolization fever, dysphagia, and transient chest pain which were managed symptomatically. After a median follow-up period of 10.5 months (range 0.5-38 months), no recurrence of
hemoptysis
was observed in 8 patients who are still alive. In 3 patients
hemoptysis
recurred and they underwent reembolization after 3, 22, and 25 months, respectively. Three subjects died of respiratory failure within 5 months from BAE. Presently, 50% of patients studied had a > or = 1 year interval free of major
hemoptysis
after the first BAE. Our experience indicates that massive and/or recurrent
hemoptysis
in CF patients can be safety and effectively managed by BAE if the procedure is performed by a skilled practitioner. The procedure was well tolerated and resulted in prolonged and satisfactory bleeding control in most patients.
...
PMID:Bronchial artery embolization in the management of hemoptysis in cystic fibrosis. 756 13
Five patients with moderate to massive
hemoptysis
who had a bronchial artery of anomalous origin or a nonbronchial systemic artery originating from the proximal subclavian artery underwent microcatheter placement through a created side hole of a 5-F catheter. All patients had pulmonary tuberculosis and had undergone bronchial artery embolization for
hemoptysis
. The side holes were made in the lesser (n = 2) or greater curvature sides (n = 3) of 5-F nonbraided Headhunter catheters. A microcatheter was passed through the side hole of the 5-F catheter into the target artery for embolization.
Polyvinyl alcohol
particles were used as the embolic material. The technical success rate was 100%, and immediate control of
hemoptysis
was achieved in all patients without complication.
...
PMID:Microcatheter placement through a side hole created in a 5-F catheter into proximal subclavian arterial branches causing hemoptysis. 1529 95