Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019079 (hemoptysis)
 6,129 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 62-year-old man presented with haemoptysis and radiographic features compatible with pulmonary tuberculosis. His course was complicated by severe haemoptysis that required surgical lobectomy. Mycobacterium xenopi was cultured from sputum and lung tissue. The post-operative course was complicated by gastro-intestinal haemorrhage and the patient died.
Tubercle 1984 Sep
PMID:Massive haemoptysis caused by Mycobacterium xenopi. 648 16

During the 3 decades 1950-1979 onset of idiopathic pulmonary haemosiderosis occurred in 10 Swedish children. Complete records were available from the eight children with onset during 1960-1979, which indicates that the yearly risk of onset is 0.24 case per million children. The first symptoms started at the mean age of 5.8 years (range: 10 months-11 years). From the beginning all children had a severe microcytic, hypochromic, sideropenic anaemia. Pulmonary symptoms were present from the beginning in four children (but haemoptysis in only one) and developed in the remaining children after 1 1/2-2 1/2 years. Various therapeutical regimens were tried. Iron therapy seemed of temporary beneficial effect and most children seemed to benefit from prednisone therapy during disease bouts, although the effect of the therapy in the long run could not be determined. The four children with onsets during the 1960s died of their disease after 2-13 years. The four children with onset during the 1970s are still alive. One of them--a 20-year-old female, has for two years complete clinical remission and has normalized haematological, X-ray and pulmonary function data.
Acta Paediatr Scand 1984 Sep
PMID:Idiopathic pulmonary haemosiderosis in Swedish children. 648 74

Two cases of infected false aneurysms of the subclavian artery in drug addicts are described. The clinical findings related to the location of these rare lesions are presented, together with an attempt to explain their pathophysiology. The signs and symptoms include a tender supraclavicular mass in an obviously septic patient associated with brachial plexus palsy, a swollen edematous arm, Horner's syndrome, and hemoptysis. Because of the complexity of symptoms, delay in diagnosis is common. It is emphasized that the recognition of this constellation of symptoms should prompt the physician to perform emergency angiography followed by immediate surgery.
J Vasc Surg 1984 Sep
PMID:Infected false aneurysms of the subclavian artery: a complication in drug addicts. 654 75

Acquired tracheobronchomalacia is seen in middle-aged and elderly people. Weakness of the tracheal and bronchial walls allows the posterior and anterior walls to draw nearer together during expiration and coughing, producing a varying obstruction. The main symptoms are dyspnoea, cough, phlegm and haemoptysis. Tracheobronchomalacia has often been diagnosed as chronic bronchitis, and the dyspnoea has also been treated as asthma, without success. Bronchoscopy, cineradiography, spirometry and intrabronchial pressure measurements are the diagnostic methods used. Tracheobronchomalacia is a progressive condition and must be taken into account in the diagnosis of obstructive pulmonary diseases and in the assessment of the working capacity of dyspnoeic patients. Treatment is preventive and symptomatic; in selected cases surgery also may be of benefit.
Eur J Respir Dis 1982 Sep
PMID:Acquired tracheobronchomalacia. 675 13

The radiologic appearance of pulmonary involvement in six cases of Behcet disease is described. Chest radiographs in five patients showed infiltrates and/or rounded opacities followed by excavation in two cases and by pleural rupture in one. Repeat chest films on four of these five patients 3 weeks to 9 months after diagnosis showed resolution of the infiltrates and the subpleural opacities. The other findings from chest radiography in three patients were rounded or lobulated opacities near the hila. Four of the six patients underwent pulmonary angiography, which in all cases showed wide-spread occlusions of pulmonary arteries, accompanied in three cases by segmental or lobular pulmonary artery aneurysms corresponding to the proximal opacities visible on the plain films. Two of the three patients who displayed pulmonary artery aneurysms died of massive hemoptysis 3 and 13 months after angiography. In the third patient, progress under medical treatment was favorable; chest film 10 months after treatment started showed complete resolution of the aneurysms. Repeat angiogram also showed partial recanalization of the occluded arteries.
AJR Am J Roentgenol 1981 Sep
PMID:Pulmonary involvement in Behcet disease. 697 70

A total of 302 Chinese patients were diagnosed on clinical and radiographic grounds by chest physicians from the Hong Kong Chest Service as having radiographically active pulmonary tuberculosis, but had sputum negative for acid-fast bacilli on 5 recent microscopical examinations. They were not given antituberculosis chemotherapy until active disease had been confirmed by positive bacteriological findings, or by radiographic or clinical deterioration during close observation. Of the 283 patients assessed up to 30 months, 200 (71%) had active disease confirmed and had chemotherapy started during the 30 months. A further 42 (15%) had evidence of changing lesions on serial chest radiography, and hence of recently active disease. A number of characteristics of the patients and of their bacteriological and radiographic status were tested singly and in combination for association with the presence of active disease confirmed on admission or at any time during the 30 months. Patients with radiographic lesions which were larger and classified as "active" on independent radiological assessment, and with a history of blood-streaked sputum or frank haemoptysis were more likely to have unquestionably active disease on admission or at some time during the 30 months, than patients without these characteristics.
Tubercle 1981 Sep
PMID:A study of the characteristics and course of sputum smear-negative pulmonary tuberculosis. 703 18

We report a case of massive hemoptysis and bilateral tension pneumothorax immediately following placement of a fiberoptic pulmonary artery catheter. We postulate air entry into a traumatic communication caused by the catheter, traversing a parenchymal artery, the contiguous airspace and the interstitial space. Dissection of air through the perivascular sheath and into tissue planes of the thorax and abdomen followed. This sequence was rapidly fatal. Tension pneumothorax should be considered if dynamic respiratory system compliance remains poor despite aggressive evacuation of blood from the trachea of a patient with a recently inserted balloon-type catheter.
Chest 1982 Sep
PMID:Massive hemoptysis and tension pneumothorax following pulmonary artery catheterization. 704 97

We reviewed the results of 146 aspiration lung biopsies (ALB) performed on 140 patients over a five-year period. A negative fiberoptic bronchoscopy in patients with a pulmonary mass lesion or infiltrate was the major indication for ALB in this group. Seventy-two patients had various malignant chest lesions, 63 had benign or inflammatory pulmonary disease. A definite diagnosis was not obtained in the remaining five patients. The diagnostic accuracy of ALB was 73.6 percent in malignant disease and 17.5 percent in benign disease with no false positive results. Of 50 patients ultimately proven to have unresectable cancer, 46 (92.6 percent) were spared the necessity of exploratory thoracotomy for diagnosis by prior ALB. Complications included pneumothorax in 30 percent necessitating chest tube drainage in 14.3 percent. Minor hemoptysis occurred in 3.4 percent, hemothorax in 0.68 percent and subcutaneous emphysema in 1.36 percent. There were no deaths directly attributable to the procedure. We conclude that ALB is a valuable procedure in the diagnosis of malignant chest lesions, sparing exploratory thoracotomy for histologic diagnosis in many patients.
Chest 1981 Sep
PMID:Aspiration biopsy in the diagnosis of pulmonary disease. 727 79

Radionuclide imaging has been successfully used clinically to determine sites of gastrointestinal hemorrhage, but its use in hemoptysis has not been studied. A dog model of intrapulmonary hemorrhage was devised. Utilizing technetium sulfur colloid, at doses of 4 and 15 mCi, bleeding rates of 0.1--0.2 cc/min were detected. In some dogs, however, significantly higher bleeding into a large bronchus, which causes a diffuse distribution of the radionuclide.
J Nucl Med 1981 Sep
PMID:Scintigraphic detection of intrapulmonary bleeding using technetium-99m sulfur colloid: concise communication. 727 22

We analyzed the records of 129 consecutive patients with hemoptysis to evaluate whether or not early (during hemoptysis or during the 48 h after hemoptysis stopped) fiberoptic bronchoscopy (FB) more frequently localized and/or diagnosed the source of bleeding and influenced clinical outcome than delayed FB (48 h or more after hemoptysis stopped). Patients were divided into 3 groups on the basis of their final diagnoses: neoplasm (31 patients), bronchitis/bronchiectasis (52 patients), and miscellaneous (46 patients). Although the likelihood of visualizing active bleeding (41 versus 8%) or its site (34 versus 11%) was significantly higher with early versus delayed FB, respectively, neither active bleeding nor a bleeding site were visualized in at least 60% of the 92 patients who underwent early FB. Definitive (endoscopic) diagnoses by early or delayed FB occurred primarily in patients with neoplasm. Clinical outcome based on the results of FB was not significantly different between the early and delayed groups. Thus, early, single FB was generally neither diagnostic nor therapeutically decisive in these patients with hemoptysis.
Am Rev Respir Dis 1981 Sep
PMID:Clinical efficacy of early and delayed fiberoptic bronchoscopy in patients with hemoptysis. 728 54


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