Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019079 (hemoptysis)
 6,129 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report a case of pulmonary suppuration due to a mixed infection of anaerobic bacterium and Actimomyces. A 49-year-old man was admitted to our hospital because of hemoptysis on March 30, 1999. A chest X-ray film showed a localized shadow in the right middle lobe, and a tumor shadow was recognized on chest CT. The anaerobic bacterium were isolated from specimens collected bronchofiberscopically. A diagnosis of pulmonary suppuration due to anaerobic bacterium was made, and treatment with sulbactam/ampicillin, followed by imipenem/cilastatin, was initiated. Although his clinical symptoms and laboratory data improved rapidly following this treatment, the abnormal finding on the chest radiographs remained, with only slight improvement. Accordingly, surgical resection of part of the right middle lobe was performed on June 29 using a video-associated thoracic surgery technique. Actinomycosis was recognized by pathological examination of the resected lesion. A revised diagnosis of pulmonary suppuration due to a mixed infection of anaerobic bacterium and Actinomyces was made. Anaerobic bacterium in the oral cavity are recognized as significant pathogens in pulmonary suppuration. In the present case, we considered anaerobic bacterium and Actinomyces aspirated from the oral cavity into the lung to have caused the pulmonary suppuration.
 ...
PMID:[Pulmonary suppuration due to a mixed infection of anaerobic bacterium and Actinomyces]. 1110 11

Empyema is often caused by Streptococcus pneumoniae, Staphylococcus aureus, and a variety of gram-negative organisms as well as anaerobes. Streptococcus gordonii (S. gordonii) is among some of the initial colonizers of the periodontal environment that is recognized to cause bacterial endocarditis. However, there are only a few case reports of S. gordonii causing empyema in the literature. We report the case of a 75-year-old male who presented with coughing up blood-tinged sputum. Physical examination revealed decreased breath sounds in the right lung base. Chest X-ray demonstrated a lower, right-sided, loculated pleural effusion. He underwent ultrasound-guided chest tube placement. The pleural fluid culture grew S. gordonii. He was started on ampicillin/ sulbactam. The follow-up computed tomography (CT) scan showed no significant improvement. Given his inability to improve with antibiotics and chest tube drainage, he was referred to an advanced care center for decortication of lung tissue.
 ...
PMID:Streptococcus gordonii Empyema: A Rare Presentation of Streptococcus gordonii Infection. 3131 38