Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019079 (hemoptysis)
6,129 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

From April 1981 to December 1988, a total of 23 patients were operated upon for the repair of an aneurysm of the descending thoracic aorta with a tridodecylmethylammonium chloride (TDMAC)-heparin-impregnated shunt. There were 20 men and 3 women. The ages ranged from 29 to 72 years with a mean of 52.3 years. The major pathological change of the aortic wall was medial cystic necrosis in 19 patients and atherosclerosis in 4. Among them, only 6 patients underwent elective surgery, while 17 patients underwent emergency operations with the surgical indication being shock in 4, oliguria in 3, persistence of chest pain in 2, massive hemoptysis in 1, rapid size progression of the aneurysm in 3, and impending rupture of the aneurysm in 4. During surgery, the aortic cross-clamping time ranged from 40 to 76 minutes with a mean of 54 minutes. Hospital death was limited to 2 patients with a mortality rate of 8.7%. Postoperative complications were noted in 5 patients, cerebrovascular accidents in 4 and transient paraparesis in 1. However, the clinical conditions recovered before those patients were discharged. The follow-up period ranged from 4 to 84 months with a mean of 32.3 months. Except for 1 patient who died of anaphylactic shock due to drug allergy, the other 20 survivors had an apparent improvement of their clinical status and life quality.
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PMID:The use of TDMAC-heparin-impregnated shunt for managing aneurysm of the descending thoracic aorta. 197 26

Two young men presented with prolonged hectic fever and chills followed by chest pain, dyspnea and hemoptysis. The chest films revealed multiple lung infiltrates, and blood cultures yielded Staphylococcus aureus. Echocardiographic examination confirmed the diagnosis of tricuspid valve endocarditis. Multiple punctate lesions in the bilateral inguinal areas and dragon tattoos over the forechest gave rise to the suspicion of drug abuse. After prolonged antimicrobial therapy, bacteremia was eliminated, and elective vegetectomy and valvuloplasty were performed on one of the patients. The other one suffered recurrent episodes of pulmonary embolism. Disappearance of the large vegetation was disclosed by echocardiography. Both of them eventually regained their health with the abstinence of drugs. This report illustrates two typical cases of infective endocarditis in drug addicts.
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PMID:Staphylococcus aureus endocarditis in drug addicts: report of 2 cases. 198 79

The objective of our study was to determine the safety of transbronchial biopsy (TBB) in nonhospitalized patients. The design was a prospective study of the consecutive cases from July 1987 until September 1988 in the setting of a university hospital of the third level with 1,800 beds. The patients were a consecutive sample of 169 patients who had 184 procedures of fiberoptic bronchoscopy (FOB) with TBB performed. They suffered from different diseases: lung nodules or masses, diffuse interstitial disease, alveolar condensation, etc. An FOB with TBB was performed in immunocompetent outpatients, who were kept under observation for four hours and then had a chest roentgenogram taken afterwards. We contacted them again after 72 hours to rule out delayed complications. In three cases, more than 100 ml of blood were obtained during the FOB, without significant hemoptysis being recorded in those patients during the observation period; chest pain occurred in 15 patients during the TBB; pneumothorax occurred in two patients (1 percent), one of whom required admission to the hospital, without requiring chest tube drainage. Other complications are reported (bronchospasm, parenchymal hemorrhage, and pneumonia). In conclusion, we consider the TBB to be a technique with a low incidence of complications for outpatients, so therefore we do not believe that admission to the hospital is mandatory for this type of patient, although we do recommend a longer observation period.
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PMID:Safety of the transbronchial biopsy in outpatients. 199 9

A group of 228 patients with cancer of the lungs admitted in the course of 15 months to the Second Clinic for TB and Respiratory Diseases was classified according to the complicating pleural exudate. At the onset or in the course of the disease the exudate developed in 24 patients (11%)--group A, in the remaining 204--group B--there is no information on an exudate. The mean age of the two groups did not differ, smoking habits were similar. Significant differences were recorded as regards the incidence of subjective complaints, in group A the patients complained significantly more frequently of dyspnoea grade III to IV, chest pain, loss of weight and oedema of the neck. As to the number with haemoptysis and exposure to cancerogens the two groups did not differ. As to subsidiary diseases, only CHOPN was more frequent in group B. Differences were recorded also in the ratio of morphological types, in group A the small-cell type was most frequent, in group B the spinocellular type. The two groups differed also as to the incidence of peripheral and central forms, which were significantly more frequent in group A. The TNM stages differed: in group A stage IV predominated, in group B there were 40% of the patients in stage I and II. Significant differences between the groups were found also as to treatment: 17.6% in group B were operated and none in group A. In group A all patients died, in group B to the day of evaluation 25 subjects survive, this difference, is, however, not significant.
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PMID:[Pleural exudates in patients with lung cancer. Comparative study]. 200 91

Endobronchial neoplastic disease is rarely encountered in patients under 20 years of age. The great majority of these lesions are carcinoids or mucoepidermoid carcinoma. Symptoms are secondary to bronchial irritation and manifest as recurrent pneumonitis, hemoptysis, persistent cough, reactive airway disease, and chest pain. Early bronchoscopy reliably enables identification and may prevent harmful sequelae resulting from delay in diagnosis. Retrospective data from four cases collected from the Tumor Registry in the Southern California Kaiser Permanente Medical Group is presented and a review of the literature is discussed.
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PMID:Endobronchial carcinoid and mucoepidermoid carcinoma in children. 200 93

A survey on pulmonary acariasis was carried out in the grain store and in the Chinese medicinal herb plant. Of 363 persons examined, 92(25.3%) were mites-positive in their sputum. 65 of them had symptoms and signs attributed to pulmonary acariasis, the incidence being 17.9%. The main clinical manifestations were productive cough, hemoptysis, chest pain, dyspnea asthma and marked eosinophilia. Roentgenogram of these cases revealed widening hilum shadow, increased and disordered lung markings, multiple cloudy shadow and nodular opacities ranging from 1-5mm in diameter scattered throughout the lower field of lungs. All the patients were treated with three courses of metronidazole. In each course a daily dose of 0.6g (0.2g tid) or 0.8g (0.4g bid) was given orally for seven days with an interval of 7-10 days between two courses. After three courses, the clinical manifestations and radiographic findings were much improved in most cases, eosinophilia dropped to normal limit, mites disappeared from sputum in 94.4% of patients. All these showed that metronidazole is rather effective in treating pulmonary acariasis.
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PMID:[Clinical manifestation and treatment of pulmonary acariasis]. 209 4

A case of pulmonary infarction presenting as aseptic cavitation was reported. Basically, the patient suffered from rheumatic heart disease, mitral stenosis and insufficiency, and atrial fibrillation with predominant right heart enlargement. Hemoptysis, chest pain and dyspnea were present. Chest film simulated a thin wall lung abscess. The clinical picture suggested aseptic cavitation, which was confirmed by 99mTc-MAA lung scan.
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PMID:Pulmonary infarction presenting as aseptic cavitation. 212 49

Thirty-eight cases of bronchial adenoma seen at Taipei VGH during 1976-88 were reviewed. Nine were carcinoid tumors, 14 were mucoepidermoid carcinomas and 15 were cylindromas. There were 21 men and 17 women. Ages ranged from 6 to 81 years with a mean of 43. Twenty-five were primary tumors of lung and 13 were metastasized from distant sites. The commonest presenting symptoms were hemoptysis, persistent cough, dyspnea and chest pain. In primary bronchial adenomas, the mean duration of symptoms was similar for carcinoids and cylindromas, around 16 months, and shortest for mucoepidermoid carcinomas (2.9 months). Single mass lesion was the most common chest X-ray finding of primary adenomas, while multiple nodules were the commonest for metastatic adenomas. Most of the primary tumors (80%) were visible by bronchoscopy, which showed predilection of trachea for cylindromas, left-sided for mucoepidermoid carcinomas and right-sided for carcinoids. The mean age at presentation was similar for all types of primary adenoma, around 44.5 years, while more younger in patients with metastatic cylindroma than mucoepidermoid carcinoma. Most of the primary adenoma were resectable, however, post-operative chemotherapy or radiotherapy was required in 4 mucoepidermoid carcinomas and 2 cylindromas. All types of bronchial adenomas showed malignant potential, mean duration before metastasis was about 2 years (3 months to 4 years), most of them were mucoepidermoid carcinomas (60%). The 5-year survival rate was 11.1% for mucoepidermoid carcinomas, 55.6% for carcinoids and 83.3% for cylindromas. We conclude that the term bronchial adenoma represents a heterogenous group of tumors with considerable malignant potential and should not be ignored by its term of benignity.
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PMID:Bronchial adenoma--a heterogenous group of tumors: report of 38 patients. 216 61

In this paper, 20 cases of teratoma of the lung (3 cases were presented and 17 reviewed) were analyzed. There were 13 males and 7 females, the age ranging from 16-47 years. The primary symptoms were: cough (19 cases, 95%), blood sputum or hemoptysis (16 cases, 80%), chest pain (12 cases, 60%), fever (7 cases, 35%) and expectoration of hair (4 cases, 20%) etc. The histogenesis, diagnosis and treatment of the disease were discussed.
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PMID:[Teratoma of the lung: report of 3 cases]. 219 71

Lymphangiomyomatosis was first reported more than forty years ago. Although its incidence is rare, its occurrence is being increasingly recognized and has been the subject of a growing number of cases reports in recent years. This study adds 2 more cases to the file. Both cases involved young women with the characteristic symptoms of dyspnea, cough, abdominal discomfort and swelling, chest pain, and hemoptysis, with abundant formation of refractory chylous, serous ascites. Although the progression of the disease differed in each case, pulmonary function was affected in a similar way by the presence of obstructive and restrictive defects and a decrease in diffusing capacity. Underlying abnormalities were dilated lymphatics, thickened lymphatic walls, and muscular proliferation of leiomyomatous origin, leading to bronchial restriction. The authors point to the subtlety required in arriving at a differentiated diagnosis of lymphangiomyomatosis lymphangioleiomyomatosis and the difference between the two conditions. They also make particular recommendations in respect to the importance of preliminary hormone receptor tests and to the wisdom to be exercised in ligating a main lymphatic duct in the chest to control the formation of ascites. Pneumothorax, a frequent manifestation of lymphangiomyomatosis, is found to be the result of chronic air trapping due to a combination of narrowing of conducting airways and disruption of normal lung parenchyma.
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PMID:Lymphangiomyomatosis--newer concepts in pathogenesis and management--case reports. 224


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