Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0019079 (hemoptysis)
 6,129 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 54-year-old man with history of chronic obstructive pulmonary disease (COPD) presented with subacute onset of chest pain, shortness of breath, productive cough with haemoptysis and night sweats. There were no fever or recent weight loss reported. The chest radiograph showed right upper lobe bullae with adjacent opacification and an emphysematous lung. Due to worsening haemoptysis and persistent chest pain, CT of the chest with contrast was performed, which revealed moderate to severe emphysema and numerous blood-filled bullae. Cardiac work-up for chest pain was negative for myocardial ischaemia and for aortic dissection. Further infectious work-ups for mycobacterial and invasive fungal infection were negative. The patient was treated for acute COPD exacerbation and responded well to the antibiotics with the resolution of haemoptysis. Follow-up CT of the chest revealed the gradual resolution of the haemorrhage, while the patient remained asymptomatic.
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PMID:Acute COPD exacerbation presenting with pronounced intrabullous haemorrhage and haemoptysis. 2995 70

Chronic obstructive pulmonary disease (COPD) exacerbation and allergic bronchopulmonary aspergillosis (ABPA), in spite of sharing common features such as airway inflammation, airflow obstruction, and mucus hypersecretion, differ significantly from each other. We report a case of ABPA that was unsuccessfully treated as a COPD exacerbation. The history of non-exertional progressive dyspnea, absence of a symptom-free interval, and hemoptysis combined with a minimal, distant smoking history and prior employment at a fertilizer plant favor a diagnosis other than COPD exacerbation. The patient's disease progression and delay in diagnosis testify to the sway of cognitive biases. This case serves as a reminder that generating a thorough differential diagnosis early in a patient's care prevents misdiagnoses and hastens the initiation of definitive therapy.
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PMID:A differential comes up short in a patient with shortness of breath. 3246 83