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Query: UMLS:C0019079 (hemoptysis)
 6,129 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A patient with pulmonary sarcoidosis had evaluation of hemoptysis. A CT scan of the chest showed bilateral upper lobe cavities and five separate mycetomas with air-crescent signs. Bronchial washings were positive on stains for fungal elements, and all cultures grew Pseudallescheria boydii. We have not seen a previous report of multiple fungus balls due to P boydii demonstrated by chest CT.
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PMID:Multiple mycetomas due to Pseudallescheria boydii. 357 75

The medical records of 433 patients with sarcoidosis were reviewed to determine the prevalence and significance of hemoptysis in this disease. Twenty-five patients (6%) were found to have hemoptysis. Nineteen of the 25 patients had mild hemoptysis, four had moderate, and two had massive hemoptysis. The clinical, roentgenographic, and laboratory features in patients with hemoptysis were compared with those from an age, race, and sex matched control group of sarcoidosis patients without hemoptysis. With the exception of eye involvement which occurred with greater frequency in control patients, no significant differences were found between the two groups. While bronchoscopy may be useful in establishing a diagnosis of endobronchial sarcoidosis, identification of a specific bleeding site is not likely in the absence of massive hemoptysis or localized radiographic abnormalities. Corticosteroid therapy may be useful to control hemoptysis in some patients.
Sarcoidosis 1987 Mar
PMID:Hemoptysis in sarcoidosis. 358 93

Major haemoptysis is a very uncommon presentation of sarcoidosis inspite of the high rate and extent of pulmonary involvement in this disease. We report a 37-year-old Nigerian who presented with cough and weight loss and in whom haemoptysis was prominent. In developing tropical countries this mode of presentation is almost invariably due to pulmonary tuberculosis. In this case the haemoptysis was found to be due to ulcerations of nasopharyngeal granulomata due to sarcoidosis. Involvement of the upper respiratory tract in itself is an uncommon finding in sarcoidosis.
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PMID:Sarcoidosis presenting with severe haemoptysis. 362 16

Sarcoidosis carries a low prevalence in Israel, and acute pleural involvement in sarcoidosis is uncommon throughout the world. We report a case of a young Israeli male of Yemenite origin who presented with atypical manifestations of sarcoidosis: pleuritic pain, hemoptysis, pruritus and alcohol-induced pain. The differential diagnosis from Hodgkin's disease was involved. Various aspects of diagnosis are discussed.
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PMID:Sarcoidosis presenting with acute pleurisy, hemoptysis, pruritus and eosinophilia. 365 75

Pulmonary aspergilloma is a potentially life-threatening disease resulting from the colonization of lung cavities by the ubiquitous fungus Aspergillus fumigatus. Complex aspergilloma, characterized by thick-walled cavities with surrounding parenchymal inflammation, is a risk factor for increased morbidity and mortality. Fifteen patients with symptomatic aspergilloma underwent major thoracic procedures at North Carolina Memorial Hospital between January 1, 1972, and December 31, 1983. Twelve of the patients had hemoptysis; in 7 it was recurrent and in 5, life threatening. Tuberculosis and sarcoidosis were the most common underlying causes of lung disease, and more than half of the patients had other coexistent serious medical illness. Eleven of the 15 patients were seen with complex aspergilloma; all of the 4 major complications and the 2 deaths occurred in these patients. Bronchopleural fistula with persistent air space was the most common serious complication, and required thoracoplasty in 3 patients. Nine patients, including 5 with complex aspergilloma, had no postoperative complications, and there were no recurrent symptoms in any of the 13 operative survivors over a mean follow-up of five years. It is concluded that aggressive pulmonary resection can provide effective long-term palliation in critically ill patients with symptomatic pulmonary aspergilloma.
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PMID:Surgical management of symptomatic pulmonary aspergilloma. 389 Jul 82

We describe 4 previously healthy patients with non-cavitated pulmonary sarcoidosis, whose presenting symptom was hemoptysis. Despite the presence of pulmonary involvement in about 90% of patients with sarcoidosis, hemoptysis as the presenting symptom is very rare and was described previously, to our knowledge, in only 5 patients.
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PMID:Hemoptysis in sarcoidosis. 401 81

During a ten-year study period, we evaluated 100 histologically-proven sarcoid patients for the development of aspergillomas. Serum precipitins against Aspergillus antigens were used to screen all patients regardless of sarcoid stage. Twelve patients had serum precipitins and were further investigated with tomography and serial serum precipitins testing. Ten of these 12 patients had aspergillomas and two patients died of massive hemoptysis. No aspergillomas occurred in stages I, II, or non-cystic stage III patients. All ten aspergillomas developed in the 19 stage III patients with cystic parenchymal damage. We believe that aspergillomas in sarcoidosis are not as rare as previously reported, but occur commonly in chronic cystic sarcoidosis. Additionally, we found serial testing for serum precipitins to be valuable both for the screening of cystic sarcoid patients for aspergillomas and for the management of this complication.
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PMID:Aspergillomas complicating sarcoidosis. A prospective study in 100 patients. 647 99

The embolization of intercostal arteries for the control of massive hemoptysis is described in two patients with bronchopleural fistulas and in one patient with sarcoidosis. Hemoptysis was controlled by embolization in all three cases, but spinal cord infarction occurred in one patient as a result of the procedure. This complication can occur even in cases where no significant blood supply to the spinal cord can be seen on preliminary arteriography, which suggests that in some patients angiographically invisible small branches play an important role in the blood supply to the spinal cord. These branches may be particularly important in cases in which the spinal blood supply is already compromised by surgery, radiation therapy, or previous embolization procedures.
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PMID:Control of massive hemoptysis by embolization of intercostal arteries. 744 46

Haemoptysis rarely occurs in sarcoidosis. Most cases usually occur in patients with advanced disease and major fibrosis. We observed 6 cases including 5 with fibrosis and 1 with inaugural unilateral lymph node involvement. Haemoptysis is a sign of gravity since it is the second most frequent cause of death described in the literature. In our series 4 of the 6 cases were fatal. Aspergillus colonization of a cavity is the most frequently found aggravating factor. Ideally, surgery is indicated but usually cannot be performed due to the patients respiratory function and the extent of the lesions. Oral drugs have little effect. Certain authors have had success with local, initially intrabronchic anti-aspergillus treatment. CT-guided application is often helpful. Embolization may stop the bleeding but in the long-term, a more or less voluminous haemoptysis often recurs. Other causes of bleeding are rare. Systemic hypervascularization of sarcoidosis lesions has been proposed as one mechanism other than infection. The cause may also be a simple granuloma. Symptomatic initial treatment by embolization is also proposed in these cases. Finally, massive haemoptysis can occur by erosion of the pulmonary artery due to a necrotic sarcoidosis lesion. In our series, surgery was impossible in three patients who died. In the three others, embolization was possible in 2 and the third underwent successful surgery.
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PMID:[Hemoptysis in sarcoidosis. Apropos of 6 cases including 4 with fatal outcome]. 756 62

Endobronchial streptokinase has been used previously to dissolve blood clots caused by massive spontaneous hemoptysis, in settings including sarcoidosis, cavitary histoplasmosis, and multiple myeloma. To our knowledge, however, the use of thrombolytic agents to dissolve clots following transbronchial biopsy has not been reported previously. We describe a patient in whom endobronchial urokinase was used for successful dissolution of clots secondary to massive bleeding after transbronchial biopsy.
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PMID:Endobronchial urokinase for dissolution of massive clot following transbronchial biopsy. 813 76


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