Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019079 (hemoptysis)
 6,129 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 19-year-old male patient presented to the emergency department with a small amount of haemoptysis preceded by coughing and sneezing. He came back from Portugal a week ago. His physical examination was unremarkable and his routine blood tests were normal apart from a slightly raised D dimer. His chest x-ray revealed a mediastinal mass, which appeared on CT as a right-sided mediastinal mass with low attenuation compressing the superior vena cava. The CT angiogram showed multiple arterial supply from the brachiocephalic, vertebral and bronchial arteries; they drained into internal jugular, subclavian and azygous system. CT-guided biopsy was performed followed by operative excision of the mass 5 weeks later. Both histology results confirmed a hyaline vascular variant of Castleman's disease with no evidence of any malignancy.
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PMID:Sorry... it was not a sore throat!! Castleman's disease in a 19-year-old, previously normal, young patient. 2270 97

Castleman's disease (CD) is a rare lympho-proliferative disorder due to faulty immune regulation resulting in proliferation of lymphatic tissue. The vascular supply to these lesions have been reported to arise from the bronchial, internal mammary and the intercostal arteries. We report a case of hemoptysis secondary to intrathoracic CD with vascular supply arising from the left inferior phrenic artery which was successfully embolised with polyvinyl alcohol (PVA) particles.
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PMID:Castleman's disease: A rare indication for endovascular therapy for hemoptysis. 2851 81