Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0019079 (hemoptysis)
 6,129 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Needle aspiration of a pulmonary mass may accurately delineate malignant from nonmalignant pulmonary lesions; however, needle aspiration may be unable to identify a specific cell type. Therefore, a retrospective review of patients undergoing needle aspiration of pulmonary masses was carried out for the years, 1979 through September 1984. A Lee needle was used, which produces a sample of tissue 1-mm in diameter suitable for histopathologic analysis as well as a cytologic specimen. A total of 87 needle biopsies were carried out, but only 46 patients later underwent resection. Five patients (6 percent) sustained a pneumothorax, and four required a chest tube. Minimal hemoptysis occurred in three patients (3 percent). Eight patients were subsequently found to have benign lesions, and there were 38 malignant tumors. Seven needle biopsies (18 percent; 7/38) were nondiagnostic and subsequently proved to be malignant. Thirty-one needle biopsies were diagnostic of malignant neoplasms (82 percent; 31/38). Twenty specimens showed the same cell type as the needle biopsy (65 percent 20/31). Eleven resected specimens disagreed with the cell type from the needle biopsy (35 percent; 11/31). In these 11 patients a change in management was indicated because of the delineation of a different cell type in only four (11 percent of all 38 patients with cancer). Mixed tumors and small cell carcinoma provide the area of most concern. Our conclusions are that needle biopsy accurately indicated a malignant neoplasm in 82 percent of the patients undergoing later resection and that the specimens from Lee needle biopsy accurately predicted the cell type in 65 percent of the specimens. The inaccurate histologic diagnosis was important clinically in only 11 percent of the patients. Overall, the needle biopsy of pulmonary lesions provided a correct decision on management in 87 percent of the cases in which biopsy provided diagnosis of a malignant neoplasm (31 patients).
 ...
PMID:Correlation between needle biopsy of lung tumors and histopathologic analysis of resected specimens. 376 62

We reviewed the charts of 48 consecutive patients who had fiberoptic bronchoscopy performed in the evaluation of hemoptysis with a normal chest roentgenogram. Fiberoptic bronchoscopy provided a diagnosis other than endobronchial inflammation in only four patients--benign fibromuscular polyp in one patient, Mycobacterium tuberculosis in 1 patient, and carcinoma in two others. A literature review revealed an overall 3 percent incidence of bronchogenic carcinoma in patients with hemoptysis and normal findings on chest roentgenogram. Other than abnormal findings on chest roentgenogram, risk factors for carcinoma in patients with hemoptysis include: (1) age greater than 40; (2) significant smoking history; and (3) duration of hemoptysis for longer than one week. We concluded that in patients with hemoptysis and normal chest x-ray film findings, routine fiberoptic bronchoscopy may not always be indicated to rule out malignancy.
 ...
PMID:Role of fiberoptic bronchoscopy in patients with hemoptysis and a normal chest roentgenogram. 396 21

We report the case histories of four patients with endobronchial metastases from breast cancer, two of whom died of resultant respiratory insufficiency. To aid in earlier diagnosis and thus permit more rapid application of specific therapy, we characterized the epidemiology and presenting symptoms of these patients and 38 additional patients with endobronchial metastases from breast carcinoma that have been reported in the literature. The average age at presentation with endobronchial metastases was 55, and the average time from diagnosis of the breast primary lesion to the endobronchial metastasis was 77 months. Cough occurred in 71% of patients; wheezing and hemoptysis occurred in 25%. Segmental atelectasis occurred in 57% on chest roentgenogram. Average survival of patients from the time of diagnosis of endobronchial metastasis was 21 months; median survival was 19 months.
 ...
PMID:Endobronchial metastases from carcinoma of the breast. 396 61

A 23-year-old man experienced hemoptysis in 1968, secondary to papillary carcinoma of the thyroid with metastasis to the lungs. The patient was treated initially with thyroidectomy and Iodine- 131 (131I), and subsequently with radical neck dissection. Following a period of fifteen years in which the patient was well clinically, he experienced recurrent hemoptysis. No other source of bleeding was identified, and the hemoptysis was attributed to the lung metastases of the thyroid carcinoma.
 ...
PMID:Hemoptysis as the sole presentation of thyroid carcinoma. 403 45

The authors report the results of a retrospective study of 427 fiberoptic bronchoscopies in patients with haemoptysis. The patients were classified into 4 groups according to the results: Group I: a specific diagnosis was made (cancer, tuberculosis, infection); 151 cases (35 p. 100); Group II: inflammatory mucosa, 172 cases (40 p. 100); Group III: normal bronchoscopy, 84 cases (20 p. 100); Group IV, only blood, 20 cases (5 p. 100). Of the 151 patients in Group I, 12 had a normal chest X-ray (8 p. 100); seven of them had bronchopulmonary carcinoma (7 out of 65 cases of cancer: 10.7 p. 100). These results show that bronchoscopy is essential in cases of haemoptysis even when the chest X-ray is normal.
 ...
PMID:[Is bronchial fiberscopy always indicated in hemoptysis? Apropos of 427 tests]. 409 57

Computed tomography (CT) was used to evaluate nine patients with bronchial adenomas: five carcinoid tumors and four adenoid-cystic carcinomas. Seven patients with lesions of the trachea or proximal bronchi presented with wheezing, hemoptysis, or obstructive pneumonitis. In such cases CT was effective in displaying the total extent of infiltrating lesions including the extraluminal component. The cases of adenoid-cystic carcinoma of the bronchi demonstrated extraluminal spread in a pattern indistinguishable from bronchogenic carcinoma. In one patient, CT demonstrated an exclusively endobronchial carcinoid tumor, and conservative resection was planned and accomplished. In two cases of carcinoid tumors that presented as solitary pulmonary nodules adjacent to bronchi in the midlung zone, CT served as a road map for the bronchoscopist. Computed tomography has been employed in the post-operative patient to evaluate for possible recurrence.
 ...
PMID:Computed tomography of bronchial adenomas. 628 81

Primary tumors of the lung rarely occur in children. However, 230 well-documented cases, including the 2 presented in this review, have been identified in the English-language literature. One hundred fifty-one tumors in these reports were classified as malignant lesions and 79 as benign neoplasms. Bronchial "adenomas" constituted the largest group; most of these lesions were of the carcinoid variety, and 8% were definitely malignant. Forty-seven cases of bronchogenic carcinoma were reported in children under 16 years of age, although there were few squamous cell tumors (12%). Fifty-six percent of the benign tumors were classified as inflammatory pseudotumor. Most of the children in this collective series were seen with symptoms related to bronchial irritation or obstruction, such as cough, hemoptysis, atelectasis, or pneumonitis. Respiratory distress was an unusual symptom that was often associated with large tumors seen in the neonatal period. Approximately 20% of the children were totally symptomatic. The limited survival data that are available indicate that leiomyosarcoma and mucoepidermoid carcinoma have a more favorable prognosis in children than in adults. Survival with bronchial carcinoid tumors (90%), bronchogenic carcinoma (30%), and pulmonary blastoma (45%) appears to parallel that for adults. The experience with pulmonary rhabdomyosarcoma, as described in this review, emphasizes the importance of early diagnosis and the use of combined modes of therapy in the approach to these malignancies. Despite the rarity of primary pulmonary neoplasms in children, this diagnosis should be considered in young patients with solitary pulmonary masses or persistent, atypical pulmonary symptoms. It is hoped that early diagnosis will result in an improved prognosis and prevent life-threatening complications.
 ...
PMID:Primary pulmonary neoplasms of childhood: a review. 634 22

We report 12 cases of well-differentiated thyroid carcinoma that invaded the trachea. In all of these cases, we performed a hemithyroidectomy, including the isthmus, with an accompanying neck dissection and resection of the trachea. Six of 12 patients experienced hemoptysis, and a diagnosis of tracheal invasion was made preoperatively in nine patients by tracheal endoscopy and computed tomography. Histologic diagnosis was confirmed by a preoperative biopsy in one case only. An end-to-end anastomosis of the trachea was performed in five patients, an anastomosis between the cricoid cartilage and the trachea was performed in five patients, and an anastomosis between the thyroid cartilage and the trachea was performed in two patients. One patient with a recurrence of tumor died of tracheal bleeding 11/2 years later. One patient died of massive gastrointestinal bleeding postoperatively. The remaining ten patients have been doing well from three months to five years two months postoperatively.
 ...
PMID:Radical operation for thyroid carcinoma invading the trachea. 647 16

A case report and review of the literature concerning endobronchial metastasis from colorectal carcinoma is discussed. Careful attention to the past history of the patient, presenting symptoms and laboratory evaluation, may lessen the diagnostic difficulty in differentiating a centrally located bronchogenic carcinoma from a metastasis to a major bronchus. In the majority of cases, the primary colorectal tumor will precede the pulmonary abnormality. The most frequently manifested symptoms are cough and hemoptysis. Radiologic findings usually consist of a collapsed lung, lobe or segment secondary to the bronchial obstruction. There appears to be equal predilection for metastatic involvement of either the right or left bronchial segments. Bronchial biopsies and comparison with the previous histology of the primary colorectal tumor are mandatory.
 ...
PMID:Endobronchial metastasis from colorectal carcinoma. 649 11

A 32-year-old woman who complained of cough and hemoptysis was found to have a metastatic trophoblastic tumor in her lungs and in a supraclavicular lymph node. A regressed primary teratoma of the ovary was considered the most likely origin of the tumor. Sputum cytology showed malignant cells, many of which were in elongated fiberlike forms and some of which had orange-staining cytoplasm. These cytologic appearances of choriocarcinoma are described and compared with the brief descriptions available in the literature. The possibility of misdiagnosis as squamous carcinoma is emphasized. The correct diagnosis is of particular importance because choriocarcinoma of gestational origin, which is similar cytologically to that of teratomatous origin, responds well to chemotherapy.
 ...
PMID:Sputum cytology of metastatic choriocarcinoma: a case report. 693 63


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>