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Query: UMLS:C0019079 (hemoptysis)
 6,129 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

There have been examined 145 patients with hemoptyses and normal x-ray findings. The majority of patients were males, smokers, more than 45 years old. Bronchoscopically the most common findings have been signs of inflammation and blood traces. The most common cause of hemoptyses has been chronic bronchitis in patients older than 45 years, and bronchoectasis in younger patients. Bronchogenous carcinoma was discovered in 8 patients: in 5 by bronchoscopic examination at hemoptysis occurence and in 3 by subsequent follow up after 8, 15 and 20 months. Pulmonary vessel malformations have been discovered in 9 patients, and cardiac diseases have been the cause of hemoptysis in 7 patients. The cause of hemoptysis remained undetected in 33 (22.8%) patients.
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PMID:[Hemoptysis in patients with normal roentgenologic findings]. 274 77

An unusual case of a 61-year-old man who had hemoptysis as the major presenting manifestation of radiation-induced thyroid carcinoma is reported. The diagnosis was made by bronchoscopic removal of a polypoid lesion that was a direct extension of tumor through the trachea. Bronchoscopy is an effective and reliable means of establishing the diagnosis in this unusual subset of patients with thyroid carcinoma invading the trachea, and should be considered as the first diagnostic procedure in a patient with a thyroid mass and hemoptysis.
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PMID:Hemoptysis as the presenting manifestation of thyroid carcinoma. A case report. 274 44

The authors report a case of broncho-pulmonary squamous cell carcinoma developed in a 59-year old woman who for 11 years had been suffering from systemic scleroderma for which she never consulted. The carcinoma was revealed by haemoptysis, dyspnoea and weight loss. It extended secondarily to the pleura. The authors have reviewed the literature on non-alveolar squamous cell carcinoma. They conclude that this type of cancer is rarely diagnosed before death and has a very poor prognosis.
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PMID:[Combination of scleroderma and non bronchiolo-alveolar bronchial carcinoma. Report of a case and short review of the literature]. 285 Nov 61

The case histories of the 49 patients who died in a series of 165 patients admitted to the Medical Unit between 1958 and 1984 with polyarteritis nodosa (PAN) were reviewed. The causes of death of the 29 men and 20 women, mean age 51.44 +/- 7.4 years, were classified into 6 groups. Infection accounted for 26.5% (13/49) of deaths, the initial site of infection being pulmonary, complicated by septicaemia in 6 cases. Cardiovascular events were responsible for death in 24.4% (11/49): terminal cardiac failure (4 cases), myocardial infarction (1 case), ventricular tachycardia (1 case), stroke (1 case), pulmonary embolism (2 cases), fulminant hemoptysis (1 case). Gastrointestinal complications were the cause of death in 16.3% (8/49): ischemic necrosis (5 cases), acute pancreatitis (2 cases), oesophageal ulceration (1 case). Renal failure was observed in 10.2% (5/49), all occurring before 1972: acute renal failure (3 cases), chronic renal failure (2 cases). Cancer was the cause of death in 10.2% (5/49): primary bronchial carcinoma (2 cases), laryngeal carcinoma (1 case), carcinoma of the vulva (1 case), bone metastases (1 case). Finally, 14.2% (7/49) could not be classified in the preceding groups. Sudden death occurred in 3 patients, shock in 1 patient, multivisceral PAN in 2 patients and anaphylactic shock in 1 patient. Three of the 12 patients who had post-mortem studies had signs of progressive vasculitis. The results are compared with other reports in the literature and the pathogenic mechanisms are discussed. The infections and cardiovascular deaths occurred early or late and were not related to the state of the activity of the vasculitis. Immunosuppressive treatment seems to play an important role in their pathogenesis.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Causes of death in systemic vasculitis of polyarteritis nodosa. Analysis of a series of 165 patients]. 290 28

Bronchial carcinoma in situ is not frequently diagnosed in a clinical setting. A bronchoscopic biopsy of a small mucosal abnormality in a patient with hemoptysis yielded a diagnosis of carcinoma in situ. The involved lobe was resected. On thorough histologic examination of the surgical specimen, no residual carcinoma could be found. To our knowledge, this is unprecedented in the literature. This case emphasizes the importance of biopsying subtle abnormalities and raises questions about the optimal management of in situ bronchial carcinoma.
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PMID:Focus of bronchial carcinoma in situ eradicated by endobronchial biopsy. 318 Aug 67

The etiologic factors of major (greater than or equal to 200 ml/24 hr) and massive (greater than or equal to 1,000 ml/24 hr) hemoptysis may well affect the outcome and, therefore, the treatment of this often life-threatening problem. the decline in the incidence of tuberculosis (TB) and bronchiectasis, along with the increase in bronchitis and neoplasia, have led to a strong institutional bias against operating on patients with major and massive hemoptysis. A retrospective case study and an extensive literature review were undertaken to critically evaluate this policy. Fifty-nine consecutive patients with major hemoptysis, 26 of whom had massive hemoptysis, were identified from 887 patients seen in our institution over a 10-year period. Only four of these 59 patients underwent surgery, while 55 were managed conservatively. Etiologic factors, operability, and bleeding rate all appeared to play a major role in outcome. No patients with bronchitis, bronchiectasis, tuberculosis, or who were on anticoagulation therapy died compared to a mortality rate of 59% in patients with carcinoma (CA) of the lung and 71% in patients with leukemia. Eleven percent of operable patients treated conservatively died compared to a 46% mortality rate for nonoperable patients. And, 9% of patients with bleeding rates less than 1,000 ml/24 hr died compared to 58% of those with greater than or equal to 1,000 ml/24 hr. Conservative management appears to have a low mortality in patients with non-tuberculosis-related major hemoptysis as well as in many patients with massive hemoptysis, especially those patients who are operable and those without neoplastic disease.
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PMID:Major and massive hemoptysis: reassessment of conservative management. 342 80

A review of bronchoscopic records over a 5 year period identified 41 patients who had undergone fibreoptic bronchoscopy after presenting with haemoptysis and a normal chest X-ray. Carcinoma of the bronchus was found in 4 patients (9.7%) and the procedure yielded a diagnosis in 8 of the 20 patients in whom a specific cause of their bleeding could be identified. The diagnostic yield is sufficiently high and the morbidity of the procedure sufficiently low to justify the investigation in patients presenting with haemoptysis and a normal chest X-ray.
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PMID:Should patients with haemoptysis and a normal chest X-ray be bronchoscoped? 345 Dec 16

A 57-year-old woman with squamous carcinoma of the right lung (hilum) developed acute massive hemoptysis with syncope and hypotension. Resuscitation was complicated by the development of massive systemic air embolus, and the patient died.
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PMID:Bronchogenic carcinoma, massive hemoptysis, and systemic air embolus. 352 16

We reviewed the records of 58 patients with haemoptysis and normal chest roentgenograms who underwent fibreoptic bronchoscopy. A diagnosis of malignancy was made in six patients at bronchoscopy. Three patients had bronchogenic squamous cell carcinoma, one a carcinoid tumour and two laryngeal carcinoma. Sputum for cytology was negative for malignant cells in all six patients. Follow-up data were available for the other 52 patients for an average period of 55.7 +/- 29.6 (SD) months. Two patients had a subsequent diagnosis of bronchogenic carcinoma at 2 and 6 years after initial evaluation. Three patients died from conditions not related to pulmonary malignancy and the remaining patients followed a benign course. Our patients come from a predominantly male, elderly population of cigarette smokers. Among such patients, we conclude that bronchoscopy is indicated in the evaluation of those with haemoptysis and a normal chest roentgenogram.
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PMID:Bronchoscopy in patients with haemoptysis and normal chest roentgenograms. 365 11

Endobronchial metastasis from nonpulmonary carcinoma is rare. A case of metastatic renal cell carcinoma is presented and the literature reviewed. Severe haemoptysis was the initial symptom leading to the finding of a bronchial polypoid mass.
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PMID:Endobronchial metastasis of renal cell carcinoma. 372 82


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